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T74916-O-Methyl Guanosine;6-O-甲基鸟苷6-O-Methyl Guanosine
6-O-Methyl Guanosine inhibit colony-forming ability in a malignant xeroderma pigmentosum cell line.
价 格:¥电议型 号:T7491产 地:中国大陆
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T74613G-quadruplex DNA fluorescence probe 1;化合物 G-quadruplex DNA fluorescence probe 1G-quadruplex DNA fluo
Compound E1, also known as G-quadruplex DNA fluorescence probe 1, is a selective fluorescent probe targeting G-quadruplex DNA. It possesses the ability to penetrate membranes and enter living cells, demonstrating low cytotoxicity [1].
价 格:¥电议型 号:T74613产 地:中国大陆
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T7423Diquafosol tetrasodium;地夸磷索四钠INS365;地夸磷索四钠|||INS365
Diquafosol Tetrasodium is a P2Y2 receptor agonist that stimulates the secretion of mucins from ocular tissues Diquafosol tetrasodium (INS365) improves tear film stability and visual function, as a topical treatment of dry eye disease.
价 格:¥电议型 号:T7423产 地:中国大陆
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T73712Metformin-d6 hydrochloride;二甲双胍-d6 盐酸盐1,1-Dimethylbiguanide-d6 hydrochloride;1,1-Dimethylbiguanide-d
Metformin-d6 hydrochloride (Metformin-d6 hydrochloride) is a deuterated form of Metformin that can be used to study Metformin metabolism in vivo, and is often used as an internal standard for Metformin.ccc_R08 can be used to study HBV infection.ccc_R08 can be used to study HBV infection.
价 格:¥电议型 号:T73712产 地:中国大陆
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T73596Guanosine triphosphate;化合物 Guanosine triphosphateGuanosine triphosphate
Guanosine triphosphate (GTP), a native nucleotide, and its derivatives may serve as specific inhibitors against COVID-19 [1].
价 格:¥电议型 号:T73596产 地:中国大陆
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T73377IGUANA-1;化合物 IGUANA-1IGUANA-1
IGUANA-1, a potent ALDH1B1 inhibitor, effectively targets this mitochondrial enzyme involved in promoting colorectal and pancreatic cancer. It exhibits significant inhibition against cancer cells.
价 格:¥电议型 号:T73377产 地:中国大陆
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T73197-Methylguanosine;7-甲基鸟苷7-Methylguanosine
7-Methylguanosine is a novel cNIIIB nucleotidase inhibitor (IC50 : 87.8 ± 7.5 μM).
价 格:¥电议型 号:T7319产 地:中国大陆
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T72727Huanglongmycin N;化合物 Huanglongmycin NHuanglongmycin N
Huanglongmycin N acts as a DNA topoisomerase I inhibitor, demonstrating an EC50 value of 14 μM.
价 格:¥电议型 号:T72727产 地:中国大陆
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T72548IGUANA-1 free base;化合物 IGUANA-1 free baseSTL5-T-0057;STL5-T-0057
IGUANA-1 free base (STL5-T-0057) acts as a selective ALDH1 B1 inhibitor, demonstrating an IC50 value of 30 nM. It efficaciously inhibits the growth of SW480 cells under both adherent and spheroid conditions, yielding IC50 values of 2.46 μM and 0.39 μM, respectively. This compound is utilized in cancer research.
价 格:¥电议型 号:T72548产 地:中国大陆
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T72421LRRK2/NUAK1/TYK2-IN-1;化合物 LRRK2/NUAK1/TYK2-IN-1LRRK2/NUAK1/TYK2-IN-1
LRRK2/NUAK1/TYK2-IN-1 (compound 226) exhibits inhibitory activity against LRRK2 (Wt), LRRK2 (G2019), TYK2, and NUAK1, demonstrating IC50 values below 10 nM. This compound is useful for research into autoimmune diseases.
价 格:¥电议型 号:T72421产 地:中国大陆
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T72325(-)-15-Deoxyspergualin;化合物 (-)-15-Deoxyspergualin(-)-15-Deoxyspergualin
(-)-15-Deoxyspergualin is a potent antitumor agent that demonstrates significant inhibition against mouse leukemia L-1210.
价 格:¥电议型 号:T72325产 地:中国大陆
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T72120Guanosine 5’-diphosphate sodium;化合物 Guanosine 5’-diphosphate sodiumGDP sodium;GDP sodium
Guanosine 5´-diphosphate (GDP) sodium is a nucleoside diphosphate known for activating the adenosine 5´-triphosphate-sensitive K+ channel and serving as a potential iron mobilizer by inhibiting the hepcidin-ferroportin interaction and modulating the interleukin-6 (IL-6)/stat-3 pathway. This compound is utilized in research focused on inflammation-related conditions, including anemia of inflammation (AI).
价 格:¥电议型 号:T72120产 地:中国大陆
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T7210Guanosine 5’-diphosphate;鸟苷-5ˊ-二磷酸GDP;GDP|||鸟苷-5ˊ-二磷酸
Guanosine 5´-diphosphate (GDP) as Potential Iron Mobilizer, Preventing the Hepcidin-Ferroportin Interaction and Modulating the Interleukin-6/Stat-3 Pathway.
价 格:¥电议型 号:T7210产 地:中国大陆
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T7206L2-Iminobiotin hydrobromide;2-亚氨基生物素盐酸盐Guanidinobiotin;2-亚氨基生物素|||Guanidinobiotin|||2-亚氨基生物素盐酸盐
2-Iminobiotin hydrobromide (Guanidinobiotin) is a cyclic guanidino analog of biotin that acts as a reversible inhibitor of inducible nitric oxide synthase (iNOS) and neuronal NOS (nNOS; Ki of 21.8 and 37.5 μM for mouse iNOS and rat nNOS, respectively).
价 格:¥电议型 号:T7206L产 地:中国大陆
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T72062-Iminobiotin;2-亚氨基生物素2-IMINOBIOTIN HYDROBROMIDE|||Guanidinobiotin;2-IMINOBIOTIN HYDROBROMIDE|||2-亚氨
2-Iminobiotin (Guanidinobiotin) is a cyclic guanidino analog of biotin that acts as a reversible inhibitor of inducible nitric oxide synthase (iNOS) and neuronal NOS (nNOS; Ki of 21.8 and 37.5 μM for mouse iNOS and rat nNOS, respectively).
价 格:¥电议型 号:T7206产 地:中国大陆
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T7201Nelociguat;化合物NelociguatBAY60-4552;N-[4,6-二氨基-2-[1-[(2-氟苯基)甲基]-1H-吡唑并[3,4-B]吡啶-3-基]-5-嘧啶]-氨基甲酸甲酯|||B
Nelociguat (BAY60-4552)(BAY60-4552) is a soluble guanylate cyclase stimulator (sGC stimulator). Soluble guanylate cyclase (sGC) is a key enzyme in the nitric oxide (NO) signalling pathway.
价 格:¥电议型 号:T7201产 地:中国大陆
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T71832CTX-0124143;CiproquazoneCTX-0124143
CTX-0124143 is a histone acetyltransferase inhibitor with an IC50 value of 1.0 μM for KAT6A.CTX-0124143 can be used to study cellular senescence.
价 格:¥电议型 号:T71832产 地:中国大陆
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T71622Duartin;化合物 DuartinDuartin
Duartin is an anti-rickettsial compound. These small molecules and the workflow, featuring a high-throughput phenotypic screen for growth inhibitors of intracellular Rickettsia spp. and machine learning models for the prediction of growth inhibition of an obligate intracellular Gram-negative bacterium, should prove useful in the search for new therapeutic strategies to treat infections from Rickettsia spp. and other obligate intracellular bacteria.
价 格:¥电议型 号:T71622产 地:中国大陆
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T7135Phenylbiguanide1-苯基双胍PBG|||N-Phenylbiguanide|||1-苯基双胍|||1-Phenylbiguanide
Phenylbiguanide (N-Phenylbiguanide) is a 5-HT3 receptor selective agonist(EC50 : 3.0±0.1 μM)
价 格:¥电议型 号:T7135产 地:中国大陆
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T71286Guaifenesin-d3;化合物 Guaifenesin-d3Guaifenesin-d3
Guaifenesin-d3 is intended for use as an internal standard for the quantification of guaifenesin by GC- or LC-MS. Guaifenesin is an expectorant. It inhibits production of mucin 5AC (MUC5AC), reduces mucus viscosity and elasticity, and increases the mucociliary transport rate of endogenous particles in primary human tracheobronchial epithelial cells in a concentration-dependent manner. Guaifenesin increases phenol red secretion, a marker of expectorant activity, in rats.3 Formulations containing
价 格:¥电议型 号:T71286产 地:中国大陆