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T5465PF-5274857PF5274857;PF-5274857 freebase;PF 5274857
PF-5274857 is an effective and selective hedgehog signaling pathway inhibitor (IC50: 5.8 nM and a Ki: 4.6 nM). PF-5274857 is a potentially attractive clinical candidate for the treatment of tumor types including brain tumors and brain metastasis driven by
价 格:¥电议型 号:T5465产 地:中国大陆
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T5164Cabozantinib hydrochlorideCabozantinib hydrochloride (849217-68-1(free base));BMS-907351;XL184;盐酸卡博替
Cabozantinib (XL184) is a potent pan-tyrosine kinases inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt4 (IC50s: 0.035, 1.3, 4.6, 7 and 6 nM).
价 格:¥电议型 号:T5164产 地:中国大陆
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T5162MRT67307 HCl (1190378-57-4(free base))盐酸MRT67307
MRT67307 is a kinase inhibitor of TBK1, MARK1-4, IKKε, and NUAK1 (IC50: 19, 27-52, 160, and 230 nM, respectively).
价 格:¥电议型 号:T5162产 地:中国大陆
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T5148Atosiban acetate (90779-69-4 free base)RWJ22164;RW22164;Atosiban acetate;醋酸阿托西班
Atosiban is an inhibitor of the hormones oxytocin and vasopressin. It is used as an intravenous medication as a labour repressant (tocolytic) to halt premature labor. Atosiban inhibits the oxytocin-mediated release of inositol trisphosphate from the myome
价 格:¥电议型 号:T5148产 地:中国大陆
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T5146Eptifibatide acetate (148031-34-9 free base)依菲巴特醋酸盐;Eptifibatide acetate
Eptifibatide, an antiplatelet drug of the glycoprotein IIb/IIIa inhibitor class, is a cyclic heptapeptide constructed from 6 amino acids and a mercaptopropionyl residue.
价 格:¥电议型 号:T5146产 地:中国大陆
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T5145Oxytocin acetate (50-56-6 free base)Oxytocin acetate;α-Hypophamine acetate;Oxytocic hormone acetate;
Oxytocin is a mammalian neurohypophysial hormone, a ligand of oxytocin receptor.
价 格:¥电议型 号:T5145产 地:中国大陆
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T5144Desmopressin acetate (16679-58-6 free base)醋酸去氨加压素;DDAVP;Desmopressin acetate
Desmopressin is the synthetic analog of the antidiuretic hormone arginine vasopressin. Vasopressin Receptor The antidiuretic properties of desmopressin have led to its use in polyuric conditions including primary nocturnal enuresis, nocturia, and diabetes
价 格:¥电议型 号:T5144产 地:中国大陆
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T5140WDR5-0103 hydrochloride[890190-22-4(free base)]WD-Repeat Protein 5-0103;WDR5-0103盐酸盐
WDR5-0103 is an effective and specific WD repeat-containing protein 5 (WDR5) antagonist (Kd: 450 nM).
价 格:¥电议型 号:T5140产 地:中国大陆
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T5129SRI-011381 hydrochlorideSRI-011381 hydrochloride [1629138-41-5(free base)]
SRI-011381, a new-type agonist of the TGF-beta signaling pathway, is utilized in the treatment of Alzheimer´s disease.
价 格:¥电议型 号:T5129产 地:中国大陆
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T5124SRT 1720 dihydrochloride[925434-55-5(free base)]
SRT 1720 is a selective activator of SIRT1 (EC1.5: 0.16 μM) and shows less potent activities on SIRT2 (EC1.5: 37 μM) and SIRT3 (EC1.5: 300 μM).
价 格:¥电议型 号:T5124产 地:中国大陆
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T5025LPralmorelin acetate 158861-67-7(free base)
Pralmorelin acetate stimulates growth hormone secretion.Pralmorelin acetate is an oral active synthetic peptide analogue of MEK. Pralmorelin acetate, an auxin releasing peptide/growth hormone secretory receptor agonist, can selectively stimulate ghrelin r
价 格:¥电议型 号:T5025L产 地:中国大陆
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T5021Leuprolide Acetate (53714-56-0 free base)Leuprolide Acetate;Leuprorelin acetate;醋酸亮脯利特
Leuprolide is an agonist at pituitary GnRH receptors. Leuprorelin is a gonadotropin-releasing hormone (GnRH) analog used to treat a wide range of sex hormone-related disorders including advanced prostatic cancer, endometriosis, and precocious puberty. Leu
价 格:¥电议型 号:T5021产 地:中国大陆
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T4998LCefpodoxime (free acid)
Cefpodoxime (free acid) is an oral, third-generation cephalosporin antibiotic. It is active against most Gram-positive and Gram-negative organisms, except Pseudomonas aeruginosa, Enterococcus, and Bacteroides fragilis.
价 格:¥电议型 号:T4998L产 地:中国大陆
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T4696BMS202 hydrochloride (1675203-84-5(free base))PD-1/PD-L1 inhibitor 2 hydrochloride
PD-1/PD-L1 inhibitor 2 is a small-molecule PD-1/PD-L1 interaction inhibitor (IC50: 18 nM). Biophysical studies demonstrate that BMS202 binds directly to PD-L1. Binding of BMS202 promotes PD-L1 dimerisation and blocks the PD-L1/ PD1 interaction.
价 格:¥电议型 号:T4696产 地:中国大陆
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T4694AG-1557 hydrochloride (189290-58-2(free base))
AG-1557 is an inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase (pIC50: 8.194).
价 格:¥电议型 号:T4694产 地:中国大陆
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T4692Protein kinase inhibitors 1 hydrochloridProtein kinase inhibitors 1 hydrochlorid (1365986-44-2(free
Protein kinase inhibitors 1 is a novel inhibitor of HIPK2 with an IC50 of 74 nM and Kd of 9.5 nM.
价 格:¥电议型 号:T4692产 地:中国大陆
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T4690Betrixaban hydrochloride(330942-05-7(free base))盐酸贝曲西班;PRT054021 hydrochloride
Betrixaban is a potent, selective, and orally efficacious factor Xa (fXa) inhibitor (IC50: 1.5 nM).
价 格:¥电议型 号:T4690产 地:中国大陆
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T4689Palosuran hydrochloride 540769-28-6(free base)ACT-058362 hydrochloride
Palosuran is a new potent and specific antagonist of the human UT receptor with an IC50 of 3.6±0.2 nM.
价 格:¥电议型 号:T4689产 地:中国大陆
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T4657LWHI-P97 HCl 211555-05-4(free base)
WHI-P97 HCl is a potent and selective JAK-3 inhibitor. WHI-P97 had an estimated Ki value of 0.09 microM from modeling studies and a measured IC50 value of 2.5 microM in EGFR kinase inhibition assays. WHI-P97 effectively inhibited the in vitro invasiveness
价 格:¥电议型 号:T4657L产 地:中国大陆
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T4613Arg-Gly-Asp TFA (99896-85-2(free base))RGD;RGD Trifluoroacetate
RGD Trifluoroacetate is a tripeptide that effectively triggers cell adhesion, addresses certain cell lines and elicits specific cell responses; binds to integrins.
价 格:¥电议型 号:T4613产 地:中国大陆