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T1158LPhenoxybenzamine;化合物 T1158LNSC-37448|||A688|||NSC 37448|||NSC37448|||A-688;NSC-37448|||A688|||NSC 37
Phenoxybenzamine is an α-1 adrenergic receptor antagonist. Phenoxybenzamine may exert a neuroprotective effect by reducing neuroinflammation after traumatic brain injury.
价 格:¥电议型 号:T1158L产 地:中国大陆
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T1158Phenoxybenzamine hydrochloride;盐酸酚苄明NCI-c01661|||NSC 37448|||Phenoxybenzamine HCl;苯氧苯札明|||NCI-c01661
Phenoxybenzamine hydrochloride (NCI-c01661) is the hydrochloride salt form of phenoxybenzamine, a synthetic, dibenzamine alpha-adrenergic antagonist with antihypertensive and vasodilatory properties. Phenoxybenzamine non-selectively and irreversibly blocks the postsynaptic alpha-adrenergic receptor in smooth muscle, thereby preventing vasoconstriction, relieving vasospasms, and decreasing peripheral resistance. Reflex tachycardia may occur and may be enhanced by blockade of alpha-2 receptors whi
价 格:¥电议型 号:T1158产 地:中国大陆
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T1153Trimethoprim;甲氧苄啶NIH 204|||BW 56-72|||NSC-106568;NIH 204|||BW 56-72|||甲氧苄啶|||NSC-106568
Trimethoprim (NSC-106568) is a Dihydrofolate Reductase Inhibitor Antibacterial. The mechanism of action of trimethoprim is as a Dihydrofolate Reductase Inhibitor, and Cytochrome P450 2C8 Inhibitor, and Organic Cation Transporter 2 Inhibitor.
价 格:¥电议型 号:T1153产 地:中国大陆
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T1147Chlorhexidine dihydrochloride;盐酸氯己定Chlorhexidine hydrochloride|||Chlorhexidine 2HCl|||NSC-185;盐酸氯己定|
Chlorhexidine dihydrochloride (NSC-185) is a disinfectant and topical anti-infective agent used also as mouthwash to prevent oral plaque.
价 格:¥电议型 号:T1147产 地:中国大陆
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T11449L2Golotimod (TFA) (229305-39-9 free base);化合物 T11449L2SCV 07 (TFA)|||Gamma-D-glutamyl-L-tryptophan (TF
Golotimod TFA (SCV 07 TFA) is an immunomodulatory peptide with antibacterial properties that significantly increases the effectiveness of anti-tuberculosis studies, stimulates thymus and splenocyte proliferation and improves macrophage function. Golotimod TFA has the potential to be used in studies of recurrent genital herpes simplex virus type 2 (HSV-2).
价 格:¥电议型 号:T11449L2产 地:中国大陆
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T11449LGolotimod;戈洛莫德Gamma-D-glutamyl-L-tryptophan|||SCV 07;Gamma-D-glutamyl-L-tryptophan|||SCV 07
Golotimod (SCV 07) is an antimicrobial dipeptide with immunomodulatory activity that significantly improves the efficacy of anti-tuberculosis therapy, induces thymic and splenic cell proliferation, modulates macrophage function, and inhibits STAT3 signaling.Golotimod has been used in the study of recurrent genital Herpes Simplex Virus 2 (HSV-2) infection and oral mucositis.
价 格:¥电议型 号:T11449L产 地:中国大陆
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T1142Clindamycin phosphate;克林霉素磷酸酯Clindamycin 2-phosphate|||Clindamycin 2-dihydrogen phosphate|||NSC 6186
Clindamycin Phosphate is the phosphate salt form of clindamycin, a semi-synthetic, chlorinated broad-spectrum antibiotic produced by chemical modification of lincomycin. Clindamycin phosphate (Clindamycin 2-dihydrogen phosphate) is used in topical preparations.
价 格:¥电议型 号:T1142产 地:中国大陆
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T11338Furamidine;化合物 T11338DB75|||NSC 305831;DB75|||NSC 305831
Furamidine is also a selective and cell-permeable protein arginine methyltransferase 1 (PRMT1) inhibitor with an IC50 of 9.4 μM. Furamidine is selective for PRMT1 over PRMT5, PRMT6, and PRMT4 (CARM1) (IC50s of 166 μM, 283 μM, and >400 μM, respectively). Furamidine (DB75) is abisbenzamidine derivative and an antiparasite agent. Furamidine is a potent, reversible and competitive tyrosyl-DNA phosphodiesterase 1 (TDP-1) inhibitor. Inhibition of TDP-1 by Furamidine is effective both with single- and
价 格:¥电议型 号:T11338产 地:中国大陆
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T11250Ezetimibe-d4;化合物 T11250SCH 58235 D4;SCH 58235 D4
Ezetimibe D4, a deuterium-labeled variant of Ezetimibe, functions as an inhibitor of Niemann-Pick C1-like1 (NPC1L1) and is recognized for its potent activation of Nrf2.
价 格:¥电议型 号:T11250产 地:中国大陆
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T1125Shikonin;紫草素NSC 252844|||Isoarnebin 4|||(+)-Shikonin|||Alkanna Red|||C.I. 75535|||Anchusa acid;NSC 2
Shikonin (Anchusa acid) is a natural product, a TMEM16A chloride channel inhibitor (IC50=6.5 μM) and selective PKM2 inhibitor. Shikonin exhibits antitumor, anti-inflammatory and wound healing activities.
价 格:¥电议型 号:T1125产 地:中国大陆
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T1124Flumethasone氟米松氟米松|||Flumetasone|||RS-2177|||NSC-54702
Flumethasone (RS-2177) is a glucocorticoid receptor agonist, with anti-inflammatory, antipruritic and vasoconstrictive properties.
价 格:¥电议型 号:T1124产 地:中国大陆
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T1123Camptothecin喜树碱NSC-100880|||Campathecin|||喜树碱|||(S)-(+)-Camptothecin|||CPT
Camptothecin (CPT) belongs to the alkaloid group of natural products and is a specific DNA topoisomerase I (Topo I) inhibitor (IC50=679 nM) with specificity. Camptothecin has antitumor activity and induces apoptosis.
价 格:¥电议型 号:T1123产 地:中国大陆
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T11229Erlotinib-d6;化合物 T11229OSI-774 D6|||NSC 718781 D6|||CP-358774 D6;OSI-774 D6|||NSC 718781 D6|||CP-358
Erlotinib is a directly acting inhibitor EGFR tyrosine kinase inhibitor with an IC50 of 2 nM for human EGFR. Erlotinib D6 is a deuterium labeled Erlotinib .
价 格:¥电议型 号:T11229产 地:中国大陆
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T11205ent-Ezetimibe;ENT-依折麦布ent-SCH 58235;ent-SCH 58235|||ENT-依折麦布
Ezetimibe is a Niemann-Pick C1-like1 (NPC1L1) inhibitor, and is a potent Nrf2 activator.ent-Ezetimibe (ent-SCH 58235) (ent-SCH 58235) is the RRS-enantiomer of Ezetimibe. Ezetimibe is a potent cholesterol absorption inhibitor.?
价 格:¥电议型 号:T11205产 地:中国大陆
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T11151Ecteinascidin-Analog-1;化合物 T11151Ecteinascidin-Analog-1
Ecteinascidins is a family of tetrahydroisoquinoline alkaloids with wide range of antitumor and antimicrobial activities. Ecteinascidin-Analog-1 is a useful intermediate for chemical sythesis of Ecteinascidin analogues.
价 格:¥电议型 号:T11151产 地:中国大陆
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T11150Ecteinascidin 770;化合物 T11150Ecteinascidine 770|||Et-770;Ecteinascidine 770|||Et-770
Ecteinascidin 770 (ET-770) inhibits U373MG cells and is a 1,2,3, 4-tetrahydroisoquinoline alkaloid with strong anticancer activity.IC50 is 4.83 nM.
价 格:¥电议型 号:T11150产 地:中国大陆
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T11139(E/Z)-BCI;化合物(E/Z)-BCINSC 150117;NSC 150117
(E/Z)-BCI (NSC-150117), a dual-specificity phosphatase 6 (DUSP6) inhibitor with anti-inflammatory properties, reduces LPS-induced inflammatory mediators and ROS production in macrophage cells by activating the Nrf2 signaling axis and inhibiting the NF-κB pathway.
价 格:¥电议型 号:T11139产 地:中国大陆
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T1110Meclizine dihydrochloride盐酸美克洛嗪Meclozine dihydrochloride|||NSC28728|||Meclizine 2HCl|||盐酸美克洛嗪
Meclizine dihydrochloride (NSC28728) is a histamine H1 antagonist used in the treatment of motion sickness, vertigo, and nausea during pregnancy and radiation sickness.
价 格:¥电议型 号:T1110产 地:中国大陆
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T11078Deschloroclozapine;氯氮平杂质Deschloroclozapine
Deschloroclozapine, a metabolite of Clozapine, is a highly potent muscarinic DREADDs agonist. Deschloroclozapine binds to DREADD receptor subtypes hM3Dq and hM4Di with Ki of 6.3 and 4.2 nM, respectively.
价 格:¥电议型 号:T11078产 地:中国大陆
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T11000Descarbamoyl cefuroxime;化合物 T11000Descarbamoyl cefuroxime
Descarbamoyl cefuroxime is also an intermediate in the synthesis of cephalosporin antibiotics. Decarbamyl cefuroxime is a degradation product of cefuroxime.
价 格:¥电议型 号:T11000产 地:中国大陆