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T11719JMV 2959 hydrochloride (925238-89-7 free base)；化合物JMV 2959 hydrochlorideJMV 2959 hydrochloride；JMV 2
JMV 2959 hydrochloride (925238-89-7 free base) is a growth hormone secretagogue receptor type 1a (GHS-R1a) antagonist with an IC50 of 32±3 nM in LLC-PK1 cells.
价 格：￥电议型 号：T11719产 地：中国大陆
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T11717JHU395；化合物JHU395JHU395
JHU395 is an orally-bioavailable prodrug of a lipophilic glutamine antagonist (GA), 6-diazo-5-oxo-L-norleucine (DON). It demonstrates delivery of DON to malignant peripheral nerve sheath tumor (MPNST) both in vitro and in vivo, resulting in significant antitumor activity in MPNST. Additionally, JHU395 exhibits plasma stability.
价 格：￥电议型 号：T11717产 地：中国大陆
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T11695N-Demethyl ivabradine hydrochloride；化合物 T11695Ivabradine metabolite N-Demethyl Ivabradine hydrochlor
N-Demethyl Ivabradine Hcl is a specific inhibitor of the funny channel.N-Demethyl Ivabradine Hcl is a metabolite of Ivabradine.
价 格：￥电议型 号：T11695产 地：中国大陆
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T116837TLC9995-0188；化合物 TLC9995-0188TLC9995-0188
Tyrosine-protein kinase ABL, IC50: 1500 nM
价 格：￥电议型 号：T116837产 地：中国大陆
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T11675Irbesartan-d4；厄贝沙坦 D4SR-47436 D4|||BMS-186295 D4；厄贝沙坦 D4|||SR-47436 D4|||BMS-186295 D4
Irbesartan D4, a deuterium-labeled variant of Irbesartan, is a highly potent and specific antagonist of the angiotensin II type 1 (AT1) receptor.
价 格：￥电议型 号：T11675产 地：中国大陆
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T1166Ellipticine；玫瑰树碱NSC 71795|||Elliptisine；玫瑰树碱|||NSC 71795|||Elliptisine
Ellipticine (Elliptisine) is a potent antineoplastic agent exhibiting multiple mechanisms of action, IC50 of 0.67±0.06, 1.25±0.13, 1.25±0.13, 0.67±0.06, 0.27±0.02, 0.49±0.04, 0.44±0.03, and 1.48±0.62 μM for Leukemia HL-60, Breast adenocarcinoma MCF-7, Breast adenocarcinoma MCF-7, Leukemia HL-60, Neuroblastoma IMR-32, Neuroblastoma UKF-NB-4, Neuroblastoma UKF-NB-3, and Glioblastoma U87 mg cell, respectively.
价 格：￥电议型 号：T1166产 地：中国大陆
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T11606ICA-105665；化合物 T11606PF-04895162；PF-04895162
ICA-105665 (PF-04895162) is a potent and orally active neuronal Kv7.2/7.3 and Kv7.3/7.5 potassium channels opener. ICA-105665 had low cytotoxic potential in human hepatocytes but inhibited liver mitochondrial function and bile salt export protein (BSEP) transport (IC50 of 311 μM). ICA-105665 can penetrate the central nervous system (CNS) and has antiseizure effects[1][2][3][4].
价 格：￥电议型 号：T11606产 地：中国大陆
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T11597LIACS-9571 Hydrochloride (1800477-30-8 free base)；化合物 T11597LIACS-9571 Hydrochloride|||ASIS-P040 Hydr
IACS-9571 Hydrochloride is a selective and potent inhibitor of TRIM24 and BRPF1, (IC50: 8 nM for TRIM24; Kds: 31 nM and 14 nM for TRIM24 and BRPF1).
价 格：￥电议型 号：T11597L产 地：中国大陆
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T11597IACS-9571；化合物 T11597ASIS-P040；ASIS-P040
IACS-9571 is a selective and potent inhibitor of TRIM24 and BRPF1, (IC50: 8 nM for TRIM24; Kds: 31 nM and 14 nM for TRIM24 and BRPF1).
价 格：￥电议型 号：T11597产 地：中国大陆
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T11595IACS-8779；化合物 T11595IACS-8779
IACS-8779 is a potent STING agonist that efficiently stimulates interferon gene activity and exhibits strong systemic antitumor effects.
价 格：￥电议型 号：T11595产 地：中国大陆
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T11495LGSK 4027；化合物 T11495LGSK 4027
GSK 4027 is a PCAF/GCN5 bromodomain chemical probe. In a time-resolved fluorescence resonance energy transfer (TR-FRET) assay, it has a pIC50 of 7.4±0.11 for PCAF.
价 格：￥电议型 号：T11495L产 地：中国大陆
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T11495GSK4028；化合物 T11495GSK4028
GSK4028 is the enantiomeric negative control of GSK4027, which is a PCAF/GCN5 bromodomain chemical probe. The pIC50 of GSK4028 is 4.9 in a TR-FRET assay.
价 格：￥电议型 号：T11495产 地：中国大陆
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T11494GSK3532795；化合物 T11494BMS-955176；BMS-955176
GSK3532795 is a potent, orally active, second-generation HIV-1 maturation inhibitor (EC50s: 10.2, 1.9, 2.7, and 13 nM for HIV-1 WT(human serum), HIV-1 WT, HIV-1 V370A, and HIV-1 ΔV370).
价 格：￥电议型 号：T11494产 地：中国大陆
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T11403LGln-AMS TFA (209543-57-7 free base)；化合物 T11403LGln-AMS TFA；Gln-AMS TFA
Gln-AMS(TFA) inhibits glutaminyl-tRNA synthetase (GlnRS) with a Ki of 1.32 μM. Gln-AMS (TFA) is a type Ia aminoacyl-tRNA synthetase (AARS) inhibitor.
价 格：￥电议型 号：T11403L产 地：中国大陆
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T11399Giredestrant；化合物GiredestrantGDC-9545；GDC-9545
Giredestrant (GDC-9545) potently competes with estradiol for binding and induces a conformational change within the ER ligand binding domain. Giredestrant has anti-tumor activity. Giredestrant, a non-steroidal ER ligand, is an orally active and selective estrogen receptor (ER) antagonist.
价 格：￥电议型 号：T11399产 地：中国大陆
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T11395GF 15；化合物 T11395GF 15
GF 15 is a potent inhibitor of centrosomal clustering in tumor cells.
价 格：￥电议型 号：T11395产 地：中国大陆
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T11388Gemilukast；吉鲁司特ONO-6950；ONO-6950
Gemilukast (ONO-6950) is an orally active and potent dual inhibitor of cysteinyl leukotriene 1 and 2 receptors (CysLT1 and CysLT2), inhibits LTC 4-induced bronchoconstriction, and is inhibitory to human CysLT1 and CysLT2, and may be used in the treatment of asthma.
价 格：￥电议型 号：T11388产 地：中国大陆
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T11386LGemcabene；化合物GemcabenePD-72953；PD-72953
Gemcabene (PD-72953) is a lipid-lowering agent with anti-inflammatory activity. Gemcabene lowers low-density lipoprotein cholesterol and triglycerides, raises high-density lipoprotein cholesterol, and decreases pro-inflammatory acute-phase protein, C-reactive protei
价 格：￥电议型 号：T11386L产 地：中国大陆
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T11386Gemcabene calcium化合物 T11386PD-72953 calcium
Gemcabene calcium , a first-in-class lipid-lowering agent, lowers low-density lipoprotein cholesterol (LDL-C), decreases triglycerides, and raises high-density lipoprotein cholesterol (HDL-C) andexerting anti-inflammatory activity, lowers pro-inflammatory acute-phase protein, C-reactive protein (CRP).
价 格：￥电议型 号：T11386产 地：中国大陆
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T11329FT895；化合物FT895FT895
FT895 is a selective and potent HDAC11 inhibitor with antifungal and antitumor activity that inhibits HDAC11 expression and limits EV71 replication in vitro.
价 格：￥电议型 号：T11329产 地：中国大陆
