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T11793KY-05009;化合物KY-05009KY-05009
KY-05009 is a chemical compound that effectively suppresses TGF-β1-induced epithelial-to-mesenchymal transition (EMT) in human lung adenocarcinoma cells, reduces TNIK protein expression and the transcriptional activity of Wnt target genes, and promotes apoptosis in cancer cells, displaying anti-cancer properties. Furthermore, it functions as an ATP-competitive Traf2- and Nck-interacting kinase (TNIK) inhibitor with a Ki of 100 nM.
价 格:¥电议型 号:T11793产 地:中国大陆
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T1173Tropisetron hydrochloride;盐酸托烷司琼SDZ-ICS 930|||Tropisetron HCl|||ICS 205-930;SDZ-ICS 930|||Tropisetro
Tropisetron hydrochloride (Tropisetron HCl) is the hydrochloride salt form of tropisetron, a selective, competitive serotonin 5-hydroxytryptamine type 3 (5-HT3) receptor antagonist, with antinauseant and antiemetic activities.
价 格:¥电议型 号:T1173产 地:中国大陆
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T11693LIT1t dihydrochloride;化合物IT1t二盐酸盐IT1t dihydrochloride
IT1t dihydrochloride inhibits CXCL12/CXCR4 interaction with IC50 of 2.1 nM. IT1t dihydrochloride is an antagonist of CXCR4.
价 格:¥电议型 号:T11693L产 地:中国大陆
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T11693IT1t;化合物 T11693IT1t
IT1t inhibits CXCL12/CXCR4 interaction with an IC50 of 2.1 nM. is a potent CXCR4 antagonist.
价 格:¥电议型 号:T11693产 地:中国大陆
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T1162Acipimox;阿昔莫司Olbemox|||K-9321;Olbemox|||K-9321|||阿西莫司|||阿昔莫司
Acipimox (K-9321) is a niacin derivative and nicotinic acid analog with activity as a hypolipidemic agent. Acipimox has special application for the treatment of hyperlipidemia in non-insulin-dependent diabetic patients.
价 格:¥电议型 号:T1162产 地:中国大陆
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T11593I-OMe-Tyrphostin AG 538;化合物T11593I-OMe-AG 538;I-OMe-AG 538
I-OMe-Tyrphostin AG 538 is a specific IGF-1R inhibitor and ATP-competitive inhibitor of PI5P4Kα (IC50: 1 ?M).I-OMe-Tyrphostin AG 538 inhibits IGF-1R-mediated signaling and exhibits preferential cytotoxicity to nutrient-deficient PANC1 cells.
价 格:¥电议型 号:T11593产 地:中国大陆
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T11493GSK3004774;化合物 T11493GSK3004774
GSK3004774 is a nonabsorbable agonist of CaSR (pEC50: 7.3, 6.6, and 6.5 for human, mouse, and rat CaSR). GSK3004774 shows an EC50 of 50 nM for human CaSR.
价 格:¥电议型 号:T11493产 地:中国大陆
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T11466GSK-2793660;化合物 T11466GSK-2793660
GSK-2793660 is an orally active and irreversible inhibitor of Cathepsin C (CTSC). GSK-2793660 is a bioactive dipeptide that can be used for the research of bronchiectasis [1] [2].
价 格:¥电议型 号:T11466产 地:中国大陆
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T11449L2Golotimod (TFA) (229305-39-9 free base);化合物 T11449L2SCV 07 (TFA)|||Gamma-D-glutamyl-L-tryptophan (TF
Golotimod TFA (SCV 07 TFA) is an immunomodulatory peptide with antibacterial properties that significantly increases the effectiveness of anti-tuberculosis studies, stimulates thymus and splenocyte proliferation and improves macrophage function. Golotimod TFA has the potential to be used in studies of recurrent genital herpes simplex virus type 2 (HSV-2).
价 格:¥电议型 号:T11449L2产 地:中国大陆
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T11449Golotimod hydrochloride (229305-39-9 free base);化合物 T11449Golotimod hydrochloride|||Gamma-D-glutamyl
Golotimod hydrochloride (SCV 07 hydrochloride) is an immunomodulating peptide with antimicrobial properties. It enhances antituberculosis therapy effectiveness, promotes thymic and splenic cell proliferation, and boosts macrophage functionality. Furthermore, it inhibits STAT3 signaling, thereby modifying the duration and intensity of oral mucositis in animal models subjected to radiation or a combination of radiation and Cisplatin. Additionally, Golotimod hydrochloride has shown potential as a t
价 格:¥电议型 号:T11449产 地:中国大陆
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T11393GET73;化合物GET73Gamma hydroxybutyric acid analogue|||GET 73;Gamma hydroxybutyric acid analogue|||GET 7
GET73 (Gamma hydroxybutyric acid analogue) is an negative allosteric modulator of mGluR5. GET73 is a naturally occurring neurotransmitter. GET73 has anti-alcohol and anxiolytic properties.
价 格:¥电议型 号:T11393产 地:中国大陆
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T1131Ivermectin;伊维菌素MK-933;MK-933|||伊维菌素
Ivermectin (MK-933) is a glutamate-gated chloride channel (GluCls) activator, with antiparasitic activity.
价 格:¥电议型 号:T1131产 地:中国大陆
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T11293(±)-Fabesetron hydrochloride;化合物 T11293FK1052 hydrochloride;FK1052 hydrochloride
FK1052 hydrochloride is a potent 5-HT3 and 5-HT4 receptor dual antagonist.
价 格:¥电议型 号:T11293产 地:中国大陆
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T11193Enalaprilat-d5 sodium;依那普利拉钠 D5MK-422 D5 Sodium Salt|||Enalaprilat D5 Sodium Salt;MK-422 D5 Sodium S
Enalaprilat D5 Sodium Salt is the deuterium labeled Enalaprilat, which is an angiotensin-converting enzyme (ACE) inhibitor.
价 格:¥电议型 号:T11193产 地:中国大陆
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T11179Elubrixin;化合物ElubrixinSB-656933;SB-656933
Elubrixin (SB-656933) inhibits neutrophil CD11b upregulation (IC50 of 260.7 nM) and shape change (IC50 of 310.5 nM). Elubrixin can be used for inflammatory diseases such as inflammatory bowel disease and airway inflammation. Elubrixin is a potent, selective, competitive, reversible and orally active CXCR2 antagonist and an IL-8 receptor antagonist.
价 格:¥电议型 号:T11179产 地:中国大陆
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T11172EIPA hydrochloride;化合物 T11172L593754 hydrochloride|||MH 12-43 hydrochloride;L593754 hydrochloride|||
EIPA hydrochloride also inhibits Na+/H+-exchanger (NHE) and macropinocytosisEIPA hydrochloride (L593754 hydrochloride) is a TRPP3 channel inhibitor with an IC50 of 10.5 μM.
价 格:¥电议型 号:T11172产 地:中国大陆
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T11093DPPH;2,2-联苯基-1-苦基肼基2,2-Diphenyl-1-picrylhydrazyl;2,2-联苯基-1-苦基肼基|||2,2-Diphenyl-1-picrylhydrazyl
DPPH (2,2-Diphenyl-1-picrylhydrazyl) is a cell-permeable, stable free radical that is commonly used to evaluate the ability of compounds to act as free radical scavengers or hydrogen donors and to measure the antioxidant activity of tissue extracts
价 格:¥电议型 号:T11093产 地:中国大陆
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T11048LDIPQUO hydrochloride;化合物DIPQUO盐酸盐DIPQUO hydrochloride(1269365-82-3 Free base);DIPQUO hydrochloride(1
DIPQUO hydrochloride is an activator of the bone marker alkaline phosphatase (ALP), with an EC50 of 6.27 μM in C2C12 cells. DIPQUO hydrochloride promotes mouse and human osteoblast differentiation via activation of p38 MAPK-β.
价 格:¥电议型 号:T11048L产 地:中国大陆
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T10993δ-Amyrenone;Α-香树脂酮Delta-Amyrone;Delta-Amyrone|||Α-香树脂酮
δ-Amyrenone (Delta-Amyrone), isolated from S. lineare, has anti-inflammatory effects.
价 格:¥电议型 号:T10993产 地:中国大陆
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T10939LL-Cystathionine;L-胱硫醚Cystathionine|||ZINC1532680|||L-(+)-Cystathionine|||Cystathionine, L-;L-胱硫醚|||C
L-Cystathionine (Cystathionine, L-) is a key nonprotein amino acid related to metabolic conditions of sulfur-containing amino acids. L-Cystathionine can be used in studies about cardiovascular protection.
价 格:¥电议型 号:T10939L产 地:中国大陆