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T10896CSRM617;化合物 T10896CSRM617
CSRM617 is a selective small molecule inhibitor of the transcription factor ONECUT2 (OC2, the main regulator of androgen receptor). The Kd in SPR analysis is 7.43 uM, which can directly bind to the OC2-HOX domain. CSRM617 induces apoptosis by cleaving the presence of Caspase-3 and PARP. CSRM617 is well tolerated in a mouse model of prostate cancer.
价 格:¥电议型 号:T10896产 地:中国大陆
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T10873CP-96486;化合物 T10873CP-96486
CP-96486 is a potent and orally active antagonist of leukotriene D4 (LTD4)/platelet activating factor (PAF) receptor (Kis: 20 and 24 nM).
价 格:¥电议型 号:T10873产 地:中国大陆
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T10872LCP 96021;化合物CP 96021CP 96021
CP 96021 is a group of 5-HT1 receptors and 5-HT2 receptors antagonists that have anti-inflammatory properties and are non-non-self anti-ulcer compounds for the treatment of gastrointestinal tract and respiratory asthma.
价 格:¥电议型 号:T10872L产 地:中国大陆
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T10872CP-96021 hydrochloride;化合物 T10872CP-96021 hydrochloride
CP-96021 hydrochloride is a potent and orally active antagonist of leukotriene D4 (LTD4)/platelet activating factor receptor (Kis: 34 nM and 37 nM).
价 格:¥电议型 号:T10872产 地:中国大陆
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T10796Chlormethiazole hydrochloride;氯美噻唑盐酸盐Clomethiazole hydrochloride;氯美噻唑盐酸盐|||Clomethiazole hydrochlori
Chlormethiazole hydrochloride is an anticonvulsant and sedative. It also has neuroprotective.
价 格:¥电议型 号:T10796产 地:中国大陆
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T10696CB2 modulator 1;化合物CB2 modulator 1CB2 modulator 1
CB2 modulator 1 is a potent CB2 modulator. It can be used for the research for immune disorders, osteoporosis, inflammation, renal ischemia.
价 格:¥电议型 号:T10696产 地:中国大陆
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T10596BR102375;化合物 T10596BR102375
BR102375 is a non-TZD PPAR γ full agonist (EC50: 0.28 μM) for the treatment of type 2 diabetes.
价 格:¥电议型 号:T10596产 地:中国大陆
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T10496Bencianol;苯西阿诺ZY15051;ZY15051|||苯西阿诺
Bencianol is a semisynthetic flavonoid with anti-spasmogenic activities.
价 格:¥电议型 号:T10496产 地:中国大陆
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T10396ATM Inhibitor-1;化合物 T10396ATM Inhibitor-1
ATM Inhibitor-1 is a highly potent, selective and orally active ATM inhibito (IC50: 0.7 nM) anti-tumor activity. It shows weak activity against mTOR (IC50, 21 μM), DNAPK (IC50, 2.8 μM), PI3Kα (IC50, 3.8 μM), PI3Kβ (IC50, 10.3 μM), PI3Kγ (IC50, 3 μM) and PI3Kδ (IC50, 0.73 μM).
价 格:¥电议型 号:T10396产 地:中国大陆
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T10296Mavorixafor trihydrochloride;化合物 T10296AMD-070 trihydrochloride;AMD-070 trihydrochloride
Mavorixafor trihydrochloride is a selective and orally available CXCR4 antagonist (IC50: 13 nM against CXCR4 125I-SDF binding) and also inhibits the replication of T-tropic HIV-1 (NL4.3 strain) in MT-4 cells and PBMCs (IC50s: 1 and 9 nM).
价 格:¥电议型 号:T10296产 地:中国大陆
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T10270BAY 2416964;化合物BAY 2416964BAY 2416964
BAY 2416964 is a potent and orally active aryl hydrocarbon receptor (AHR) antagonist(example 192, IC50: 341 nM). It has the potential for cancer treatment.
价 格:¥电议型 号:T10270产 地:中国大陆
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T10261AGN 196996;化合物AGN 196996AGN 196996
AGN 196996 is a potent and selective inhibitor of RARα (Ki: 2 nM).AGN 196996 has very low affinity for RARβ and RARγ, with a Ki of 1087 nM and 8523 nM, respectively.
价 格:¥电议型 号:T10261产 地:中国大陆
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T10259AGI-25696;化合物AGI-25696AGI-25696
AGI-25696 is an inhibitor of methionine adenosyltransferase 2A (MATA2). AGI-25696 blocks the growth of MTAP-deleted tumors in vivo and can be used for studies about the treatment of cancer.
价 格:¥电议型 号:T10259产 地:中国大陆
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T101967α-Hydroxy-4-cholesten-3-one;化合物 T101967α-Hydroxy-4-cholesten-3-one
7α-Hydroxy-4-cholesten-3-one is an intermediate in the synthesis of bile acids from cholesterol. It is a PXR agonist. 7α-Hydroxy-cholest-4-en-3-one is a biomarker for bile acid loss and other diseases associated with defective bile acid biosynthesis.It is the physiological substrate for CYP8B1.
价 格:¥电议型 号:T10196产 地:中国大陆
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T10096L2(2S,3R)-Voruciclib hydrochloride;化合物 T10096L2(2S,3R)-Voruciclib hydrochloride (1253731-24-6 free bas
(2S,3R)-Voruciclib hydrochloride is the (2S,3R)-enantiomer of Voruciclib. It is an orally active CDK inhibitor.
价 格:¥电议型 号:T10096L2产 地:中国大陆
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T10096LVoruciclib;化合物VoruciclibVoruciclib
Voruciclib is an orally active and selective CDK inhibitor (Ki: 0.626 nM-9.1 nM). Voruciclib represses the expression of MCL-1 in multiple models of diffuse large B-cell lymphoma. Voruciclib effectively blocks CDK9, the transcriptional regulator of MCL-1.
价 格:¥电议型 号:T10096L产 地:中国大陆
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T10096(2S,3R)-Voruciclib;化合物 T10096(2S,3R)-Voruciclib
(2S,3R)-Voruciclib is the (2S,3R)-enantiomer of Voruciclib. It is an orally active CDK inhibitor.
价 格:¥电议型 号:T10096产 地:中国大陆
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T0996Ethynodiol diacetate;双醋炔诺醇Ethynodiol acetate|||8080 CB;Ethynodiol acetate|||双醋炔诺醇|||8080 CB
Ethynodiol diacetate (Ethynodiol acetate) is a synthetic progestational hormone used alone or in combination with estrogens as an oral contraceptive.
价 格:¥电议型 号:T0996产 地:中国大陆
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T0969Doramectin;多拉菌素Dectomax|||Cyclohexylavermectin B1;Dectomax|||Cyclohexylavermectin B1|||多拉菌素
Doramectin (Dectomax) is an antiparasitic agent.
价 格:¥电议型 号:T0969产 地:中国大陆
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T0968Paclitaxel;紫杉醇Taxol|||NSC 125973;Taxol|||紫杉醇|||NSC 125973
Paclitaxel (Taxol) is a natural product and a microtubule polymer stabilizer. Paclitaxel has anti-tumor activity and causes cell death by inducing mitotic arrest, apoptosis, and cell autophagy.
价 格:¥电议型 号:T0968产 地:中国大陆