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T16759Ritanserin；利坦丝林R 55667；利坦丝林|||R 55667
Ritanserin (R 55667) is a highly effective, relatively selective, long-acting antagonist of 5-HT2 receptor (IC50: 0.9 nM), less active on Histamine H1, Dopamine D2, Adrenergic α1, Adrenergic α2 receptors.
价 格：￥电议型 号：T16759产 地：中国大陆
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T16756Risarestat；利沙司他CT 112；CT 112
Risarestat (CT-112) is a potent aldose reductase inhibitor and thyroid hormone receptor (TR) antagonist for the treatment of hypoglycemia.
价 格：￥电议型 号：T16756产 地：中国大陆
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T16684Puromycin aminonucleoside维生素E醋酸酯维生素E醋酸酯|||NSC 3056
Puromycin aminonucleoside (NSC-3056) increases podocyte permeability by modulating ZO-1 in an oxidative stress-dependent manner.
价 格：￥电议型 号：T16684产 地：中国大陆
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T16656Propynol Ethoxylate；化合物 T16656Propynol Ethoxylate
Propynol Ethoxylate is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T16656产 地：中国大陆
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T1656LVandetanib Fumarate；化合物 T1656LHSDB 8198|||Zactima|||Caprelsa|||ZD 6474|||Vandetanib；HSDB 8198|||Zact
Vandetanib Fumarate is an orally available tyrosine kinase inhibitor. Vandetanib Fumarate works by blocking RET (REarranged during Transfection), vascular endothelial growth factor receptor (VEGFR-2, VEGFR-3), and epidermal growth factor receptor and to a lesser extent VEGFR-1, which are important targets in thyroid cancer (TC).
价 格：￥电议型 号：T1656L产 地：中国大陆
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T16569Praliciguat；化合物PraliciguatIW-1973；IW-1973
Praliciguat (IW-1973) stimulates sGC in HEK-293 cells (EC50: 197 nM). Praliciguat is an effective and orally active soluble guanylate cyclase stimulator. It also enhances NO signaling and acts as a vasodilator.
价 格：￥电议型 号：T16569产 地：中国大陆
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T16568PR-924；化合物 T16568PR-924
PR-924 is a selective inhibitor of tripeptide epoxyketone immunoproteasome subunit LMP-7 (IC50: 22 nM). PR-924 inhibits growth and triggers apoptosis in multiple myeloma (MM) cells. PR-924 has antitumor activities. PR-924 covalently modifies proteasomal N-terminal threonine active sites.
价 格：￥电议型 号：T16568产 地：中国大陆
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T16567PQR530；化合物PQR-530PQR-530；PQR-530
PQR530 is a highly potent dual pan-PI3K/mTORC1/2 inhibitor. PQR530 inhibited protein kinase B (PKB, pSer473) and ribosomal protein S6 (pS6, pSer235/236) phosphorylation with IC50 values of 0.07 μM. It also showing antitumor activity.
价 格：￥电议型 号：T16567产 地：中国大陆
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T16566Propyl pyrazole triol；化合物Propyl pyrazole triolPPT；PPT
Propyl pyrazole triol (PPT) is a selective agonist of estrogen receptor alpha. The relative binding affinity of Propyl pyrazole triol for ERα (ERα: 49%) around 410 times higher compared with estrogen receptor beta (ERβ: 0.12%).
价 格：￥电议型 号：T16566产 地：中国大陆
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T16565Ppc-1；化合物 T16565Ppc-1
Ppc-1 is a chemical compound known for its inhibitory effects on the Gram-negative periodontopathogen Porphyromonas gingivalis. It acts as a mitochondrial uncoupler, enhancing mitochondrial oxygen consumption without affecting ATP production. Additionally, Ppc-1 serves as a cell-permeate inhibitor of interleukin-2 (IL-2). This compound exhibits various beneficial activities, including anti-obesity, antibacterial, and anti-inflammatory properties.
价 格：￥电议型 号：T16565产 地：中国大陆
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T16564PPADS tetrasodium；化合物PPADS四钠盐PPADS tetrasodium
PPADS tetrasodiuma is a potent P2X receptor antagonist and inhibitor of the inverse mode of Na/Ca?? exchange in guinea pig airway smooth muscle and is neuroprotective against glutamate/NMDA toxicity.PPADS tetrasodiuma inhibits P2X1, P2X-2, P2X-3, and P2X- 5. 5.
价 格：￥电议型 号：T16564产 地：中国大陆
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T16563LPozanicline hydrochloride；化合物Pozanicline hydrochloridePozanicline hydrochloride
Pozanicline hydrochloride is an orally bioavailable nicotinic acetylcholine receptor (nAChR) agonist with a Ki of 16.7 nM for binding to [3H]cytisine sites[1]. Pozanicline hydrochloride is an α4β2-selective nAChR agonist, which binds to rat brain α4β2 nAChR with a Ki of 17 nM while binding to α7 nAChR is insignificant[2].
价 格：￥电议型 号：T16563L产 地：中国大陆
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T16563Pozanicline；化合物 T16563ABT-089；ABT-089
Pozanicline reverses nicotine withdrawal-induced cognitive deficits, may be an effective component of novel therapeutic strategies for nicotine addiction. Pozanicline selectively activate neuronal nicotinic acetylcholine receptor (nAChR) subtypes, is a novel cholinergic agent that is a partial agonist at α4β2 nAChRs (Ki=16 nM). It shows high selectivity for α6β2 and α4α5β2 nAChR subtypes, the binding affinity (Ki, rat) for Pozanicline to [3H] cytisine sites is 16.7 nM .
价 格：￥电议型 号：T16563产 地：中国大陆
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T16562Ponceau 4R胭脂红Acid Red 18|||New Coccine
Ponceau 4R (Acid Red 18) is a synthetic strawberry red azo dye that is a food colorant dye used in a variety of food products. It is stable to light, heat and acid, but fades in the presence of ascorbic acid. It is usually synthesized from aromatic hydrocarbons.
价 格：￥电议型 号：T16562产 地：中国大陆
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T16561Polyoxyethylene stearate；聚氧乙烯硬脂酸酯POES；POES|||聚氧乙烯硬脂酸酯
Polyoxyethylene stearate (POES) is an agent of non-ionic emulsifying.
价 格：￥电议型 号：T16561产 地：中国大陆
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T16560Poloxin；化合物PoloxinPoloxin
Poloxin is a non-ATP competitive Polo-like Kinase 1 inhibitor. It targets the polo-box domain (IC50: appr 4.8 μM).
价 格：￥电议型 号：T16560产 地：中国大陆
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T1656Vandetanib凡德他尼ZD6474|||凡德他尼
Vandetanib (ZD6474) is a potent inhibitor of VEGFR2 (IC50: 40 nM). It also inhibits VEGFR3 and EGFR.
价 格：￥电议型 号：T1656产 地：中国大陆
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T16556PNU-142633化合物 T16556PNU 142633|||PNU142633
PNU-142633 has anti-migraine efficacy. PNU-142633 is a high affinity and selective 5-HT1D receptor agonist (Kis of 6 nM and > 18 000 nM for human 5-HT1D receptor and human 5-HT1B receptor, respectively).
价 格：￥电议型 号：T16556产 地：中国大陆
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T16515PF 750；化合物PF 750PF-750|||UNII-7756CPP14K|||ZINC27647189；PF-750|||UNII-7756CPP14K|||ZINC27647189
PF 750 (ZINC27647189) is a selective and covalent inhibitor of FAAH. PF 750 shows IC50s varying from 16.2 to 595 nM in different incubation times.
价 格：￥电议型 号：T16515产 地：中国大陆
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T16511PF2562；化合物 T16511PF2562
PF2562 is a dopamine D1 ligand. It is used as a dopamine D1 agonist or partial agonist. PF2562 binds to human D1 receptor (Ki: 113 nM). PF2562 shows activity against human D1 cAMP (EC50: 568 nM in HTRF assay).
价 格：￥电议型 号：T16511产 地：中国大陆
