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T16483PF-05105679;化合物PF-05105679PF-05105679
PF-05105679 is a selective TRPM8 antagonist (IC50 = 103 nM). PF-05105679 can be used in research on cold-related pain.
价 格:¥电议型 号:T16483产 地:中国大陆
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T16475Pexacerfont化合物PexacerfontBMS-562086
Pexacerfont (BMS-562086) is a selective antagonist of the corticotropin-releasing factor receptor (IC50: 6.1±0.6 nM for the human CRF1 receptor).
价 格:¥电议型 号:T16475产 地:中国大陆
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T16407Osajin化合物 T16407NSC 21565|||CID 95168
Osajin is the major bioactive iso avone present in the fruit of Maclura pomifera. It has antitumor, antioxidant, and anti-inflammatory activities.
价 格:¥电议型 号:T16407产 地:中国大陆
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T16356Glyoxalic acid化合物 T16356Oxalaldehydic acid|||NSC 27785|||Formylformic acid
Glyoxalic acid is an organic compound. It is both an aldehyde and a carboxylic acid.
价 格:¥电议型 号:T16356产 地:中国大陆
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T16276NBD-556;化合物NBD-556NBD-556
NBD-556 is a small molecule mimetic of CD4. NBD-556 recognizes the HIV-1 envelope protein gp120 and induces restructuring of gp120 analogous to CD4 binding.
价 格:¥电议型 号:T16276产 地:中国大陆
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T16256N3-PEG3-C2-PFP ester;化合物 T16256N3-PEG3-C2-PFP ester
N3-PEG3-C2-PFP ester is a 3-unit polyethylene glycol (PEG) linker devoid of cleavable bonds. It is commonly employed in the synthesis of antibody-drug conjugates (ADCs).
价 格:¥电议型 号:T16256产 地:中国大陆
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T16156MT 63-78;化合物MT 63-78MT 63-78
MT 63-78 is a specific and effective direct AMPK activator (EC50: 25 μM). MT 63-78 blocks prostate cancer growth by inhibiting the lipogenesis and mTORC1 pathways. MT 63-78 has antitumor effects. MT 63–78 also causes cell mitotic arrest and apoptosis.
价 格:¥电议型 号:T16156产 地:中国大陆
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T16133MRK-560;化合物MRK-560MRK-560
MRK-560 is an effective and brain-penetrant inhibitor of γ-secretase.
价 格:¥电议型 号:T16133产 地:中国大陆
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T16126Monepantel;化合物 MonepantelAAD1566|||PPL-1;AAD1566|||PPL-1
Monepantel (AAD1566) is an organic anthelmintic and nicotinic acetylcholine receptor antagonist from roundworms and esophagostomies that is widely used for de-worming in agriculture and livestock.
价 格:¥电议型 号:T16126产 地:中国大陆
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T16105ML132;化合物 T16105NCGC 00185682;NCGC 00185682
ML132 is an effective and selective inhibitor of caspase 1 (IC50: 0.316 nM).
价 格:¥电议型 号:T16105产 地:中国大陆
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T16095MK-4256化合物 T16095MK 4256|||MK4256
MK-4256 is an effective and selective SSTR3 antagonist (IC50s: 0.66 nM and 0.36 nM in human and mouse receptor binding assays, respectively).
价 格:¥电议型 号:T16095产 地:中国大陆
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T16056Methyltetrazine-DBCO;化合物 T16056Methyltetrazine-DBCO
Methyltetrazine-DBCO is a non-cleavable linker utilized in the synthesis of antibody-drug conjugates (ADCs)[1].
价 格:¥电议型 号:T16056产 地:中国大陆
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T15956Mal-amido-PEG4-NHS ester化合物Mal-amido-PEG4-NHS esterN-[15-[(2,5-二氧代-1-吡咯烷基)氧基]-15-氧代-3,6,9,12-四氧杂十五烷-
Mal-amido-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in PROTAC synthesis[1].
价 格:¥电议型 号:T15956产 地:中国大陆
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T1591Ancitabine hydrochloride盐酸环胞苷NSC 145668 HCl|||盐酸环胞苷|||Cyclocytidine hydrochloride|||Cyclo-CMP hydroc
Ancitabine hydrochloride (NSC 145668 HCl) is the hydrochloride salt of a cytarabine congener prodrug with antineoplastic activity. Upon administration, ancitabine is slowly hydrolyzed into cytarabine. Subsequently, cytarabine is converted to the triphosphate form within the cell and then competes with cytidine for incorporation into DNA. Because the arabinose sugar sterically hinders the rotation of the molecule within DNA, DNA replication ceases, specifically during the S phase of the cell cycl
价 格:¥电议型 号:T1591产 地:中国大陆
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T15856m-PEG3-CH2-alcohol;化合物 T15856m-PEG3-CH2-alcohol
m-PEG3-CH2-alcohol is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T15856产 地:中国大陆
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T15815LY3295668;化合物AK-01AK-01;AK-01
LY3295668 (AK-01) is a selective inhibitor of Aurora A with Kis of 0.8 nM and 1038 nM for Aurora A and B, respectively.
价 格:¥电议型 号:T15815产 地:中国大陆
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T15806LY2562175;化合物LY2562175LY2562175
LY2562175 is an effective and selective FXR agonist (EC50: 193 nM).
价 格:¥电议型 号:T15806产 地:中国大陆
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T1574LEtoricoxib HCl;化合物 T1574LL-791456 monohydrochloride salt|||L791456 hydrochloride|||L-791456 hydrochl
Etoricoxib HCl is a synthetic, nonsteroidal anti-inflammatory drug. Etoricoxib specifically binds to and inhibits the enzyme cyclooxygenase-2, resulting in inhibition of the conversion of arachidonic acid into prostaglandins.
价 格:¥电议型 号:T1574L产 地:中国大陆
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T1574Etoricoxib;依托考昔Arcoxia|||MK-663|||Tauxib|||L-791456|||Nucoxia|||Desvenlafaxine;Arcoxia|||MK-663|||Ta
Etoricoxib (MK-663) is a synthetic, nonsteroidal anti-inflammatory drug (NSAID) with antipyretic, analgesic, and potential antineoplastic properties. Etoricoxib specifically binds to and inhibits the enzyme cyclooxygenase-2 (COX-2), resulting in inhibition of the conversion of arachidonic acid into prostaglandins. Inhibition of COX-2 may induce apoptosis and inhibit tumor cell proliferation and angiogenesis.
价 格:¥电议型 号:T1574产 地:中国大陆
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T15699L-Thyroxine sodium salt pentahydrate;L-甲状腺素钠五水合物Sodium levothyroxine pentahydrate|||Levothyroxine;左旋
L-Thyroxine sodium salt pentahydrate, also known as Levothyroxine, is a synthetic hormone utilized in the study of hypothyroidism. It is biologically activated into Triiodothyronine (T3) from its original form, L-Thyroxine (T4), through conversion by DIO enzymes.
价 格:¥电议型 号:T15699产 地:中国大陆