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T14953Chloroquinoxaline sulfonamide;化合物 Chloroquinoxaline sulfonamideNSC-339004|||Chloroquinoxaline;NSC-33
Chloroquinoxaline sulfonamide (Chloroquinoxaline) is a topoisomerase II alpha/beta toxin with antitumor activity and immunosuppressive properties that inhibits the proliferation of B16 melanoma cells in mice, and can be used to study metastatic colorectal cancer. It can be used to study metastatic colorectal cancer.
价 格:¥电议型 号:T14953产 地:中国大陆
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T14947CHDI-390576;化合物 CHDI-390576CHDI-390576
CHDI-390576 is a CNS-permeable, selective and potent dibenzoyl isohydroxamic acid class IIa histone deacetylase (HDAC) inhibitor that inhibits class IIa HDAC 4, HDAC 5, HDAC 7, HDAC 9, and can be used in cancer research.
价 格:¥电议型 号:T14947产 地:中国大陆
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T14920CE-224535;化合物CE-224535PF-04905428;PF-04905428
CE-224535 (PF-04905428) is a selective antagonist of P2X7 receptor. CE-224535 can be used in disease-modifying antirheumatic studies.
价 格:¥电议型 号:T14920产 地:中国大陆
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T14909CCX140;化合物CCX140CCX140-B;3-三氟甲基-4-氯-N-[2-[7H-吡咯并[2,3-D]嘧啶-4-羰基]-5-甲基-3-吡啶基]苯磺酰胺|||CCX140-B
CCX140 (CCX140-B) (CCX140-B) is an antagonist of CCR2.
价 格:¥电议型 号:T14909产 地:中国大陆
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T14908CCT367766;化合物CCT367766CCT367766
CCT367766 is a potent, PROTAC-based, third-generation, iso-functional pirin-targeted protein degradation probe (PDP) that depletes pirin expression at low concentrations.CCT367766 has an IC50 value of 490 nM for the CRBN-DDB1 complex.CCT367766 has a good affinity for recombinant pirin and CRBN. CCT367766 has a good affinity for recombinant pirin and CRBN, with Kd values of 55 nM and 120 nM, respectively. cct367766 is a potent orally active protein that reduces the expression of pirin at low conc
价 格:¥电议型 号:T14908产 地:中国大陆
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T14907CCT251545;化合物CCT251545CCT251545
CCT251545 is an potent and oral-bioavailable WNT signaling inhibitor(IC50 of 5 nM in 7dF3 cells).
价 格:¥电议型 号:T14907产 地:中国大陆
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T14906CCT251455;化合物 T14906CCT251455
CCT251455 is an inhibitor of mitotic kinase monopolar spindle 1 (MPS1; IC50: 3 nM).
价 格:¥电议型 号:T14906产 地:中国大陆
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T14905CCT251236;化合物 CCT251236CCT251236
CCT251236 is a cell-based phenotypic high-throughput screening (HTS) chemical probe developed to screen for inhibitors of the HSF1 stress pathway.CCT251236 exhibits antimyeloma activity and inhibits HSF1.
价 格:¥电议型 号:T14905产 地:中国大陆
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T14904CCT244747;化合物 T14904CCT244747
CCT244747 is a CHK1 inhibitor (IC50: 7.7 nM) and also abrogates G2 checkpoint (IC50: 29 nM).
价 格:¥电议型 号:T14904产 地:中国大陆
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T14903CCT129957;化合物CCT129957CCT129957
CCT129957 is a novel and potent phospholipase C-γ (PLC-γ) inhibitor with an IC50 of about 3 μM and a GC50 of 15 μM.CCT129957 exhibits anticancer activity and inhibits Ca2+ release in squamous cells.
价 格:¥电议型 号:T14903产 地:中国大陆
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T14902CCT020312;化合物CCT020312CCT020312
CCT020312 is a selective activator of EIF2AK3 and PERK. CCT020312 durably inhibits cell proliferation and elicits the phosphorylation of EIF2A.
价 格:¥电议型 号:T14902产 地:中国大陆
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T14901CCT-251921;化合物CCT-251921CCT-251921
CCT-251921 is a potent, selective, and orally bioavailable CDK8 inhibitor (IC50: 2.3 nM).
价 格:¥电议型 号:T14901产 地:中国大陆
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T14900CCR2-RA-[R]化合物CCR2-RA-[R](5R)-4-乙酰基-1-(4-氯-2-氟苯基)-5-环己基-1,5-二氢-3-羟基-2H-吡咯-2-酮
CCR2-RA-[R] is a C-C chemokine receptor type 2 (CCR2) allosteric antagonist (IC50: 103 nM).
价 格:¥电议型 号:T14900产 地:中国大陆
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T1490Gestodene;孕二烯酮SHB 331|||WL 70;SHB 331|||WL 70|||孕二烯酮
Gestodene (WL 70) is a progestogen hormonal contraceptive.
价 格:¥电议型 号:T1490产 地:中国大陆
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T14894CC-90003;化合物CC-90003CC-90003
CC-90003 is a selective inhibitor of ERK 1/2. It has antitumor activity.
价 格:¥电议型 号:T14894产 地:中国大陆
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T14890Cbz-NH-PEG5-C2-acid;化合物 T14890Cbz-NH-PEG5-C2-acid
Cbz-NH-PEG5-C2-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T14890产 地:中国大陆
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T14856Calcipotriol;卡泊三醇MC 903|||Calcipotriene;MC 903|||卡泊三醇|||Calcipotriene
Calcipotriol (MC 903) is a synthetic VitD3 analogue. Which has a high affinity for the vitamin D receptor.
价 格:¥电议型 号:T14856产 地:中国大陆
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T1485Methotrexate;甲氨蝶呤NCI-C04671|||WR19039|||Amethopterin|||CL14377;NCI-C04671|||WR19039|||Amethopterin||
Methotrexate (WR19039) is a folate analog, an inhibitor of the dihydrofolate reductase DHFR. Methotrexate has antimetabolic, antitumor, and immunosuppressive activities, and is commonly used in rheumatoid arthritis and various tumors.
价 格:¥电议型 号:T1485产 地:中国大陆
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T1484LPerindopril erbumine;培哚普利叔丁胺S9490-3|||Perindopril tert-butylamine salt;培哚普利叔丁胺|||培哚普利叔丁胺盐|||S9490-3|
Perindopril erbumine (S9490-3) is the tert-butylamine salt of perindopril, the ethyl ester of a non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. Upon hydrolysis, Perindopril erbumine (S9490-3) is converted to its active form perindoprilat, inhibiting ACE and the conversion of angiotensin I to angiotensin II; consequently, angiotensin II-mediated vasoconstriction and angiotensin II-stimulated aldosterone secretion from the adrenal cortex are inhibited a
价 格:¥电议型 号:T1484L产 地:中国大陆
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T14790Bromo-PEG2-C2-azide;化合物 T14790Bromo-PEG2-C2-azide
Bromo-PEG2-C2-azide is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
价 格:¥电议型 号:T14790产 地:中国大陆