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  • T14871Carboxyamidotriazole Orotate；化合物Carboxyamidotriazole OrotateL-651582 Orotate|||CAI Orotate；L-651582

    Carboxyamidotriazole Orotate (L-651582 Orotate) is a cytostatic inhibitor of non-voltage-operated calcium channels and calcium channel-mediated signaling pathways. Carboxyamidotriazole Orotate (L-651582 Orotate) is the orotate salt form of Carboxyamidotriazole (CAI), an orally bioavailable signal transduction inhibitor that in vitro has been shown to possess antileukaemic activities. Carboxyamidotriazole Orotate shows anti-tumor, anti-inflammatory, and antiangiogenic effects.

    价 格：￥电议型 号：T14871产 地：中国大陆

  • T14858Calicheamicin；卡奇霉素Calicheamicin γ1；Calicheamicin γ1|||卡奇霉素

    Calicheamicin (Calicheamicin γ1) is an antitumor antibiotic and is a DNA synthesis inhibitor. It also is a cytotoxic agent that causes double-strand DNA breaks.

    价 格：￥电议型 号：T14858产 地：中国大陆

  • T14758Boc-NH-PEG8-propargyl；化合物 T14758Boc-NH-PEG8-propargyl

    Boc-NH-PEG8-propargyl is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

    价 格：￥电议型 号：T14758产 地：中国大陆

  • T14685BMS-986158；化合物BMS-986158BMS-986158

    BMS-986158 is a highly effective BET inhibitor, demonstrating IC50 values of 6.6 nM in NCI-H211 small cell lung cancer (SCLC) cells and 5 nM in MDA-MB231 triple negative breast cancer (TNBC) cells.

    价 格：￥电议型 号：T14685产 地：中国大陆

  • T14658Bis-propargyl-PEG5；化合物 T14658Bis-propargyl-PEG5

    Bis-propargyl-PEG5 serves as a PEG-based PROTAC linker, facilitating the synthesis of PROTACs. This chemical compound is particularly employed in the synthesis of carbohydrate receptors (SCRs) with anti-Zika activity[1].

    价 格：￥电议型 号：T14658产 地：中国大陆

  • T14589Biotin-PEG3-acid化合物Biotin-PEG3-acid18-[(3AS,4S,6AR)-六氢-2-氧代-1H-噻吩并[3,4-D]咪唑-4-基]-14-氧代-4,7,10-三氧杂-13

    Biotin-PEG3-acid is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs.Biotin-PEG3-acid is a heterobiofunctional biotin PEG derivative containing a carboxylic acid group. The hydrophilic PEG spacer arm imparts water solubility that is transferred to the biotinylated molecule. PEG Linkers may be useful in the development of antibody drug conjugates and drug delivery methods.

    价 格：￥电议型 号：T14589产 地：中国大陆

  • T14588Biotin-PEG2-NHS ester；化合物 T14588Biotin-PEG2-NHS ester

    Biotin-PEG2-NHS ester is a biotinylated, polyethylene glycol (PEG)-based linker, which is utilized in PROTAC synthesis for the purpose of biotin attachment[1].

    价 格：￥电议型 号：T14588产 地：中国大陆

  • T14587Biotin-PEG2-NH-Boc；化合物 T14587Biotin-PEG2-NH-Boc

    Biotin-PEG2-NH-Boc is a PEG-based PROTAC linker labelled with biotin, which enables its application in PROTAC synthesis[1].

    价 格：￥电议型 号：T14587产 地：中国大陆

  • T14586Biotin-PEG2-Mal；化合物 T14586Biotin-PEG2-Mal

    Biotin-PEG2-Mal is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

    价 格：￥电议型 号：T14586产 地：中国大陆

  • T14585Biotin-PEG2-C6-azide；化合物 T14585Biotin-PEG2-C6-azide

    Biotin-PEG2-C6-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTAC.

    价 格：￥电议型 号：T14585产 地：中国大陆

  • T14584Biotin-PEG2-C4-alkyne；化合物 T14584Biotin-PEG2-C4-alkyne

    Biotin-PEG2-C4-alkyne is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

    价 格：￥电议型 号：T14584产 地：中国大陆

  • T14583Biotin-PEG2-azide；化合物 T14583Biotin-PEG2-azide

    Biotin-PEG2-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

    价 格：￥电议型 号：T14583产 地：中国大陆

  • T14582Biotin-PEG2-acid；化合物 T14582Biotin-PEG2-acid

    Biotin-PEG2-acid is a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

    价 格：￥电议型 号：T14582产 地：中国大陆

  • T14581Biotin-PEG12-acid；化合物 T14581Biotin-PEG12-acid

    Biotin-PEG12-acid is a PEG-based PROTAC linker labeled with biotin, designed for synthesis of PROTACs[1].

    价 格：￥电议型 号：T14581产 地：中国大陆

  • T14580Biotin-PEG11-amine；化合物 T14580Biotin-PEG11-amine

    Biotin-PEG11-amine is a PEG-based linker with biotin labeling which finds application in the synthesis of PROTACs[1].

    价 格：￥电议型 号：T14580产 地：中国大陆

  • T1458Epalrestat；依帕司他ONO2235；ONO2235|||依帕斯他|||依帕司他

    Epalrestat (ONO2235), an aldose reductase inhibitor, is well tolerated in Long-term therapy. It can effectually ameliorate the associated symptoms of diabetic neuropathy and delay the progression of the disease, particularly in patients with limited microangiopathy and good glycemic control.

    价 格：￥电议型 号：T1458产 地：中国大陆

  • T14558BI-1950；化合物 T14558BI-1950

    BI-1950 is a highly potent lymphocyte function associated antigen-1 (LFA-1) inhibitor and the LFA-1 is an essential component in normal immune system function and a target for drug discovery[1].

    价 格：￥电议型 号：T14558产 地：中国大陆

  • T14506BAY 60-6583；化合物BAY 60-6583BAY 60-6583

    BAY 60-6583 is a potent, high-affinity adenosine A2B receptor agonist (EC50 = 3 nM) with affinity for A2B receptors that exceeds that for A1, A2A, and A3 receptors.BAY 60-6583 is cardioprotective in a model of myocardial ischemia.The Ki values for BAY 60-6583 binding to mouse, rabbit, and dog A2BAR were 750 nM, 340 nM, and 330 nM, respectively. The Ki values of BAY 60-6583 binding to A2BAR in mice, rabbits and dogs were 750 nM, 340 nM and 330 nM respectively.

    价 格：￥电议型 号：T14506产 地：中国大陆

  • T14493Balapiravir化合物 T14493R1626|||Ro 4588161

    Balapiravir (R1626, Ro 4588161) is the prodrug of a nucleoside analogue inhibitor of the hepatitis C virus (HCV) RNA-dependent RNA polymerase (R1479, RG1479). IC50 Value: Target: HCV Balapiravir was discontinued for safety reasons in 28-36% of patients (most often for lymphopenia) and the percentage of patients with serious adverse events (especially hematological, infection, ocular events) was dose related. Balapiravir (R1626) is the tri-isobutyrate ester prodrug of R1479 under clinical develop

    价 格：￥电议型 号：T14493产 地：中国大陆

  • T14458Azido-PEG5-Boc；化合物 T14458Azido-PEG5-Boc

    Azido-PEG5-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

    价 格：￥电议型 号：T14458产 地：中国大陆

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