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T6166TelatinibBay 57-9352;替拉替尼
Telatinib is an effective inhibitor of VEGFR2/3, c-Kit, and PDGFRα. The IC50s of Telatinib forVEGFR2/3, c-Kit and PDGFRα are 6 nM/4 nM, 1 nM, and 15 nM, respectively.
价 格:¥电议型 号:T6166产 地:中国大陆
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T6165Bardoxolone MethylTP-155;NSC 713200;甲基巴多索隆;CDDO Methyl ester;RTA 402
Bardoxolone Methyl, an IKK inhibitor, exhibits effective proapoptotic and anti-inflammatory activities.
价 格:¥电议型 号:T6165产 地:中国大陆
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T6163Salirasib沙利雷塞;法尼基硫代水杨酸;FTS;Farnesyl Thiosalicylic Acid;S-Farnesylthiosalicylic acid
Salirasib(Ki=2.6 μM), an effective competitive prenylated protein methyltransferase (PPMTase) inhibitor, inhibits Ras methylation with potential antineoplastic activity.
价 格:¥电议型 号:T6163产 地:中国大陆
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T6162BS-181 hydrochlorideBS-181 HCl
BS-181 HCl is a highly selective CDK7 inhibitor with IC50 of 21 nM. It is more than 40-fold selective for CDK7 than CDK1, 2, 4, 5, 6, or 9.
价 格:¥电议型 号:T6162产 地:中国大陆
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T6161Tubastatin A HydrochlorideTubastatin A HCl;TSA HCl
Tubastatin A HCl is an effective and specific HDAC6 inhibitor (IC50: 15 nM). It has selectivity (>1000-fold) against all other isozymes except HDAC8 (>57-fold).
价 格:¥电议型 号:T6161产 地:中国大陆
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T6160VU 0364439
VU 0364439 is a mGlu4 positive allosteric modulator (C50: 19.8 nM).
价 格:¥电议型 号:T6160产 地:中国大陆
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T6159LY-2584702 free base
LY2584702 is a selective, ATP-competitive p70S6K inhibitor(IC50: 4 nM).
价 格:¥电议型 号:T6159产 地:中国大陆
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T6158LDN-193189 HClLDN193189 Hydrochloride
LDN193189 hydrochloride is a selective BMP type I receptor kinases inhibitor.
价 格:¥电议型 号:T6158产 地:中国大陆
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T6157Devimistat辛酸;6,8-Bis(benzylthio)octanoic acid;CPI613;CPI-613;CPI 613
CPI-613, a lipoate analog, inhibits mitochondrial enzymes pyruvate dehydrogenase (PDH) and α-ketoglutarate dehydrogenase, disrupts tumor cell mitochondrial metabolism. It has potential chemopreventive and antineoplastic activities, and has been used in tr
价 格:¥电议型 号:T6157产 地:中国大陆
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T6156Ruxolitinib (S enantiomer)S-Ruxolitinib;INCB018424;INCB18424;Ruxolitinib S enantiomer;环丙基[4-[3-(1H-咪
Ruxolitinib S enantiomer is the S-enantiomer of Ruxolitinib. Ruxolitinib is the first potent, selective JAK1/2 inhibitor.
价 格:¥电议型 号:T6156产 地:中国大陆
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T6152PD318088
PD318088 is a non-ATP competitive allosteric MEK1/2 inhibitor, binding simultaneously with ATP in a region of the MEK1 active site that is adjacent to the ATP-binding site.
价 格:¥电议型 号:T6152产 地:中国大陆
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T6149YH239-EE
YH239-EE, the ethyl ester of YH239, is a potent p53-MDM2 antagonist and an apoptosis inducer.
价 格:¥电议型 号:T6149产 地:中国大陆
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T6147NortadalafilDemethyl Tadalafil;去甲基他达那非
Nortadalafil is demethyl Tadalafil, which is a PDE5 inhibitor, treating erectile dysfunction (ED) ; and under the name Adcirca for the treatment of pulmonary arterial hypertensio.
价 格:¥电议型 号:T6147产 地:中国大陆
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T6146Dorsomorphin dihydrochloride6-[4-[2-(1-哌啶基)乙氧基]苯基]-3-(4-吡啶基)吡唑并[1,5-A]嘧啶;Dorsomorphin (Compound C) 2
Dorsomorphin is a potent, selective and ATP-competitive AMPK inhibitor (Ki: 109 nM) and does not exhibit significant activity on structurally related kinases.
价 格:¥电议型 号:T6146产 地:中国大陆
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T6145ZM39923 hydrochlorideZM 39923 HCl;JAK3 Inhibitor IV
ZM 39923 HCl is an JAK1/3 inhibitor with pIC50 of 4.4/7.1, almost no activity to JAK2 and modestly potent to EGFR; also found to be sensitive to transglutaminase.
价 格:¥电议型 号:T6145产 地:中国大陆
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T6144KB-R7943 mesylateKB-R7943
KB-R7943 mesylate is a widely used inhibitor of the reverse Na+/Ca2+ exchanger (NCXrev) with IC50 of 5.7±2.1 μM.
价 格:¥电议型 号:T6144产 地:中国大陆
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T6143PI-103PI103;PI 103
PI-103 is a potent, cell-permeable, ATP-competitive inhibitor of PI3K family members (IC50s: 2/3/3/15/30/23 nM for p110α/β/δ/γ, mTOR, and DNA-PK).
价 格:¥电议型 号:T6143产 地:中国大陆
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T6141IMD-0354IMD 0354;IKK2 Inhibitor V
IMD-0354 is an IKKβ inhibitor and inhibits IκBα phosphorylation in NF-κB pathway.
价 格:¥电议型 号:T6141产 地:中国大陆
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T6140SB-334867 free baseSB334867A free base;SB334867;SB 334867;SB-334867
SB-334867 is a selective orexin-1 (OX1) receptor antagonist.
价 格:¥电议型 号:T6140产 地:中国大陆