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T74328STING agonist-8 dihydrochloride;化合物 STING agonist-8 dihydrochlorideSTING agonist-8 dihydrochloride
STING Agonist-8 Dihydrochloride (Compound 5-AB) is a highly effective STING agonist, exhibiting an EC50 value of 27 nM in THP1-Dual KI-hSTING-R232 cells.
价 格:¥电议型 号:T74328产 地:中国大陆
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T73981Deschloro Cetirizine dihydrochloride;化合物 Deschloro Cetirizine dihydrochlorideDeschloro Cetirizine di
Deschloro Cetirizine Dihydrochloride is an impurity of Cetirizine, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine. It functions as a specific, orally active, and long-acting histamine H1-receptor antagonist.
价 格:¥电议型 号:T73981产 地:中国大陆
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T73962Cetirizine Impurity C dihydrochloride;化合物 Cetirizine Impurity C dihydrochlorideCetirizine Impurity C
Cetirizine Impurity C dihydrochloride, a specific impurity of Cetirizine, is associated with a second-generation antihistamine that serves as the carboxylated metabolite of hydroxyzine. This compound acts as a specific, orally active, and long-acting antagonist of the histamine H1-receptor [1] [2].
价 格:¥电议型 号:T73962产 地:中国大陆
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T73932Fructosyl-lysine dihydrochloride;化合物 Fructosyl-lysine dihydrochlorideFructosyl-lysine dihydrochlorid
Fructosyl-lysine dihydrochloride (Fructoselysine), an Amadori glycation product, forms through the Maillard reaction between glucose and lysine. This compound serves as the precursor to glucosepane, a lysine–arginine protein cross-link, which is significant in the detection of diabetes [1].
价 格:¥电议型 号:T73932产 地:中国大陆
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T73705Imnopitant dihydrochloride;化合物 Imnopitant dihydrochlorideImnopitant dihydrochloride
Imnopitant dihydrochloride is a neurokinin NK1 receptor antagonist [1] .
价 格:¥电议型 号:T73705产 地:中国大陆
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T73677SR 142948 dihydrochloride;化合物 SR 142948 dihydrochlorideSR 142948 dihydrochloride
SR 142948 dihydrochloride is a selective, orally active, non-peptide neurotensin receptor (NT) antagonist, featuring IC50 values of 1.19 nM, 0.32 nM, and 3.96 nM in h-NTR1-CHO cells, HT-29 cells, and adult rat brain, respectively. It effectively inhibits NT-induced inositol monophosphate formation in HT-29 cells (IC50 = 3.9 nM) and blocks NT-induced hypothermia, analgesia, and steering behavior in vivo. Furthermore, it demonstrates blood-brain barrier permeability, positioning it as a potential
价 格:¥电议型 号:T73677产 地:中国大陆
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T7309TAS-103 dihydrochloride;化合物TAS-103 (dihydrochloride)TAS-103 (dihydrochloride)|||BMS-247615 dihydroch
TAS-103 dihydrochloride (BMS-247615 dihydrochloride) is a novel anticancer agent targeting both topoisomerase (Topo) I and Topo II.
价 格:¥电议型 号:T7309产 地:中国大陆
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T7277SB 242084;化合物SB 242084 dihydrochloride hydrateSB 242084 dihydrochloride hydrate;6 - 氯-2,3 - 二氢- 5 -甲
SB 242084 dihydrochloride hydrate is a psychoactive drug and research chemical which acts as a selective antagonist for the 5HT2C receptor.
价 格:¥电议型 号:T7277产 地:中国大陆
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T72276EG01377 dihydrochloride;化合物 EG01377 dihydrochlorideEG01377 dihydrochloride
EG01377 dihydrochloride is a potent, bioavailable and selective inhibitor of neuropilin-1 (NRP1) , with a K d of 1.32 μM, and IC 50 s of 609 nM for both NRP1-a1 and NRP1-b1 . EG01377 dihydrochloride has antiangiogenic, antimigratory, and antitumor effects [1] .
价 格:¥电议型 号:T72276产 地:中国大陆
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T72270WYE-687 dihydrochloride;化合物 WYE-687 dihydrochlorideWYE-687 dihydrochloride
WYE-687 dihydrochloride is an ATP-competitive inhibitor of mTOR, demonstrating potent activity with an IC 50 value of 7 nM. It effectively suppresses the activation of both mTORC1 and mTORC2. Additionally, WYE-687 exhibits inhibitory effects on PI3Kα and PI3Kγ, with IC 50 values of 81 nM and 3.11 μM, respectively.
价 格:¥电议型 号:T72270产 地:中国大陆
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T72269TAK-960 dihydrochloride;化合物 TAK-960 dihydrochlorideTAK-960 dihydrochloride
TAK-960 dihydrochloride is an orally administered, selective polo-like kinase 1 (PLK1) inhibitor, exhibiting a potent IC 50 of 0.8 nM. It also targets PLK2 and PLK3 with IC 50 values of 16.9 and 50.2 nM, respectively. This compound effectively inhibits the proliferation of a broad range of cancer cell lines and demonstrates substantial efficacy against various tumor xenografts.
价 格:¥电议型 号:T72269产 地:中国大陆
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T72239DDO-2093 dihydrochloride;化合物 DDO-2093 dihydrochlorideDDO-2093 dihydrochloride
DDO-2093 dihydrochloride, a potent inhibitor of MLL1-WDR5 protein-protein interactions (IC50=8.6 nM; Kd=11.6 nM), exhibits antitumor activity. It selectively inhibits the catalytic activity of the MLL complex.
价 格:¥电议型 号:T72239产 地:中国大陆
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T72238SRT 1720 dihydrochloride;化合物 SRT 1720 dihydrochlorideSRT 1720 dihydrochloride
SRT 1720 dihydrochloride is a compound that selectively and effectively activates SIRT1 when taken orally, with an EC50 value of 0.10 μM. It exhibits lower potency towards SIRT2 and SIRT3.
价 格:¥电议型 号:T72238产 地:中国大陆
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T72186Tariquidar dihydrochloride;化合物 Tariquidar dihydrochlorideXR9576 dihydrochloride;XR9576 dihydrochlori
Tariquidar dihydrochloride, also known as XR9576 dihydrochloride, is a potent, specific P-glycoprotein (P-gp) inhibitor exhibiting high affinity (Kd = 5.1 nM).
价 格:¥电议型 号:T72186产 地:中国大陆
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T72112Clozapine N-oxide dihydrochloride氯氮平N-氧化盐酸氯氮平N-氧化盐酸
Clozapine N-oxide dihydrochloride is a derivative of Clozapine and an agonist of human muscarinic design receptors (DREADDs) that crosses the blood-brain barrier.Clozapine N-oxide dihydrochloride induces activation of DREADD receptors hM3Dq and hM4Di. Clozapine N-oxide dihydrochloride induces activation of DREADD receptors hM3Dq and hM4Di.
价 格:¥电议型 号:T72112产 地:中国大陆
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T72067DPTN dihydrochloride;DPTN盐酸盐DPTN dihydrochloride
DPTN dihydrochloride is a potent and selective A3AR antagonist with Ki values of 1.65, 9.61 and 8.53 nM in human, mouse and rat, respectively.
价 格:¥电议型 号:T72067产 地:中国大陆
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T7195GSK369796 Dihydrochloride;化合物GSK369796 DihydrochlorideN-tert-butylisoquine;N-tert-butylisoquine
GSK369796 Dihydrochloride (N-tert-butylisoquine),is an anti-malaria drug candidate. is an affordable and effective antimalarial and inhibits hERG potassium ion channel repolarization(IC50 of 7.5 μM)
价 格:¥电议型 号:T7195产 地:中国大陆
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T71928Nordimaprit dihydrochloride;化合物 Nordimaprit dihydrochlorideNordimaprit dihydrochloride
Nordimaprit dihydrochloride is a metabolite of Dimaprit -- a histamine analog and selective H2 histamine receptor agonist.
价 格:¥电议型 号:T71928产 地:中国大陆
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T7153Vanoxerine dihydrochloride;伐诺司林二盐酸盐GBR-12909 dihydrochloride|||I893 dihydrochloride;GBR-12909 dihydr
Vanoxerine dihydrochloride (GBR-12909 dihydrochloride) is a potent inhibitor that blocks dopamine uptake (IC50 : 1-51 nM)
价 格:¥电议型 号:T7153产 地:中国大陆
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T71523Norbinaltorphimine;化合物 nor-Binaltorphimine dihydrochlorideNorbinaltorphimine
nor-Binaltorphimine dihydrochloride is a long-acting potent and highly selective kappa opioid receptor antagonist.
价 格:¥电议型 号:T71523产 地:中国大陆