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T40581TIE-2/VEGFR-2 kinase-IN-2;TIE-2/VEGFR-2 kinase-IN-2TIE-2/VEGFR-2 kinase-IN-2
TIE-2/VEGFR-2 kinase-IN-2 is a powerful inhibitor of both VEGFR2 and Tie-2 kinases, displaying noteworthy pIC 50 values of 8.61 and 8.56, respectively. This compound acts as an anti-angiogenic agent, making it highly relevant for cancer research.
价 格:¥电议型 号:T40581产 地:中国大陆
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T40520Thiophene-2Thiophene-2Thiophene-2|||TP2
Thiophene-2 (TP2) is a targeted inhibitor of polyketide synthase 13 (Pks13), specifically designed to disrupt mycolic acid biosynthesis. By doing so, it effectively induces rapid cell death in mycobacteria. Thiophene-2 demonstrates notable anti-tuberculosis activity and exhibits a minimum inhibitory concentration (MIC) value of 1 μM against Mycobacterium tuberculosis.
价 格:¥电议型 号:T40520产 地:中国大陆
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T40388Methyl 5-hydroxypyridine-2-carboxylate;5-羟基-2-吡啶甲酸甲酯Methyl 5-hydroxypyridine-2-carboxylate
Methyl 5-hydroxypyridine-2-carboxylate, a phenolic acid identified in the stems of Mahonia fortune, demonstrates in vitro inhibitory effects on nitric oxide (NO) production.
价 格:¥电议型 号:T40388产 地:中国大陆
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T40314(2α,3β)-Olean-12-ene-2,3-diol;(2α,3β)-Olean-12-ene-2,3-diol(2α,3β)-Olean-12-ene-2,3-diol
(2α,3β)-Olean-12-ene-2,3-diol (Compound 3) is a triterpenoid compound that possesses a lupane, oleanane, and ursane skeleton.
价 格:¥电议型 号:T40314产 地:中国大陆
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T3S2007MRE-269;3-氧代-12-烯-28-乌苏酸3-氧代-12-烯-28-乌苏酸|||ACT-333679|||ACT-333679|||MRE-269|||MRE-269|||MRE 269|||M
MRE-269 (ACT-333679) is an orally available and long-acting prostacyclin receptor agonist prodrug. MRE-269(ACT-333679) is used for the treatment of pulmonary arterial hypertension. MRE-269(ACT-333679) is an active metabolite of Selexipag (S253150).
价 格:¥电议型 号:T3S2007产 地:中国大陆
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T39916GNE-274;GNE-274GNE-274
GNE-274, a non-degrader compound structurally similar to GDC-0927 (an ER degrader), serves as a partial ER agonist in breast cancer cell lines without triggering ER turnover. Notably, GNE-274 enhances chromatin accessibility at ER-DNA binding sites, unlike GDC-0927. Acting as a potent inhibitor of the ER-ligand binding domain (LBD), GNE-274 exhibits potential for cancer research purposes.
价 格:¥电议型 号:T39916产 地:中国大陆
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T39517Suvodirsen;SuvodirsenWVE-210201;WVE-210201
Suvodirsen (WVE-210201) is an oligonucleotide compound with potential applications in the study of Duchenne muscular dystrophy (DMD).
价 格:¥电议型 号:T39517产 地:中国大陆
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T38559Competence-Stimulating Peptide-2 (CSP-2);Competence-Stimulating Peptide-2 (CSP-2)Competence-Stimulat
Competence-Stimulating Peptide-2 (CSP-2) is a quorum sensing signal peptide synthesized by Streptococcus pneumoniae. ComD2, a compatible receptor of CSP-2, exhibits an EC 50 value of 50.7 nM.
价 格:¥电议型 号:T38559产 地:中国大陆
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T38419Difelikefalin;DifelikefalinCR-845|||FE-202845;CR-845|||FE-202845
Difelikefalin (CR-845; FE-202845) is a peripherally restricted, selective agonist of the kappa opioid receptor (KOR). It exhibits anti-inflammatory properties and holds promise for modulating pruritus in conditions associated with chronic kidney disease.
价 格:¥电议型 号:T38419产 地:中国大陆
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T38395Pyrrole-2-carboxaldehyde;2-吡咯甲醛Pyrrole-2-carboxaldehyde
Pyrrole-2-carboxaldehyde exhibits distinctive vibrational and electronic properties which serve to validate its dimeric state in the solid phase and monomeric state in the solution phase.
价 格:¥电议型 号:T38395产 地:中国大陆
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T38167BE-24566B;BE-24566BBE-24566B
BE-24566B is a polyketide fungal metabolite originally isolated fromS. violaceusniger.1It is active againstB. subtilis,B. cereus,S. aureus,M. luteus,E. faecalis, andS. thermophilus(MICs = 1.56, 1.56, 1.56, 1.56, 3.13, and 3.13 μg/ml, respectively). BE-24566B is an endothelin (ET) receptor antagonist (IC50s = 11 and 3.9 μM for ETAand ETBreceptors, respectively).2
价 格:¥电议型 号:T38167产 地:中国大陆
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T373465-Hydroxytoluene-2,4-disulphonic acid diammonium;5-Hydroxytoluene-2,4-disulphonic acid diammonium5-H
5-Hydroxytoluene-2,4-disulphonic acid diammonium, an impurity of Policresulen, is a significant NS2B/NS3 protease inhibitor, exhibiting an IC50 value of 0.48 μg/mL. It inhibits DENV2 virus replication in BHK-21 cells effectively, with an IC50 of 4.99 μg/mL. Policresulen functions as a competitive inhibitor, marginally impacting the protease´s stability[1].
价 格:¥电议型 号:T37346产 地:中国大陆
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T3693DHFR-IN-3;化合物 DHFR-IN-37-bromoquinazoline-2,4-diamine;7-bromoquinazoline-2,4-diamine|||7-溴-2,4-二氨基喹唑
DHFR-IN-3 (7-bromoquinazoline-2,4-diamine) is an active biochemical.
价 格:¥电议型 号:T3693产 地:中国大陆
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T368705,6-dihydro-5-Fluorouracil;5-氟二氢嘧啶-2,4-二酮5-fluorodihydrouracil|||5-Fluoro-dihydro-pyrimidine-2,4-dio
5,6-dihydro-5-Fluorouracil (5-FUH2) is an inactive metabolite of 5-FU and can be used for the study of organismal metabolism.
价 格:¥电议型 号:T36870产 地:中国大陆
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T36718Tie2 Inhibitor 7Tie2 Inhibitor 7Tie-2 Inhibitor 7|||Tie2 Inhibitor 7
Tie2 Inhibitor 7 blocks Tie2 kinase activity with a Ki value of 1.3 μM.. It has been shown to inhibit angiopoietin 1-induced Tie2 autophosphorylation and downstream signaling with an IC50 value of 0.3 μM. This compound can prevent endothelial cell tube formation and aberrant vessel growth in a rat model of Matrigel-induced choroidal neovascularization.
价 格:¥电议型 号:T36718产 地:中国大陆
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T35072-CHLORO-5-CYANOPYRAZINE;2-氯-5-氰基吡嗪5-Chloropyrazine-2-carbonitrile;5-Chloropyrazine-2-carbonitrile||
2-CHLORO-5-CYANOPYRAZINE (5-Chloropyrazine-2-carbonitrile) is an active biochemical.
价 格:¥电议型 号:T3507产 地:中国大陆
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T35036Vancide 26;化合物 T35036NSC-5337|||Vancide-26|||Vancide 26 EC|||NSC 5337|||NSC5337;NSC-5337|||Vancide-2
Vancide 26 is a bioactive chemical.
价 格:¥电议型 号:T35036产 地:中国大陆
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T33066Lysine-2-naphthylamide;化合物 T33066Lysine-2-naphthylamide
Lysine-2-naphthylamide is a bioactive chemical.
价 格:¥电议型 号:T33066产 地:中国大陆
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T32286JE-2178;化合物 T32286JE2178;JE2178
JE-2178 is compound with high bioavailability .
价 格:¥电议型 号:T32286产 地:中国大陆
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T32285JE-2147;化合物 T32285JE2147|||AG 1776|||AG1776|||JE 2147|||AG-1776;JE2147|||AG 1776|||AG1776|||JE 2147|
JE-2147 belongs to a type of compound known as hybrid peptides. The compound contains at least two different kinds of amino acids (alpha, beta, gamma, delta) linked to each other through a peptide bond.
价 格:¥电议型 号:T32285产 地:中国大陆