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T11412IPN60090;化合物IPN60090GLS1-IN-1;GLS1-IN-1
IPN60090 is a novel, potent, orally bioavailable, renal-type glutaminase (GLS1)-specific inhibitor with an IC50 value of 31 nM for GLS1. IPN60090 has potential anticancer and immunostimulant/immunomodulatory activity, selectively targets, binds, and inhibits human glutaminase, and can be used to study GLS1-mediated diseases.
价 格:¥电议型 号:T11412产 地:中国大陆
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T11191EN6;化合物EN6EN6
EN6-mediated ATP6V1A modification decouples the v-ATPase from the Rags, leading to inhibition of mTORC1 signaling, increased lysosomal acidification and activation of autophagy. EN6 clears TDP-43 aggregates, a causative agent in frontotemporal dementia, in a lysosome-dependent manner. EN6 is a small-molecule in vivo activator of autophagy that covalently targets cysteine 277 in the ATP6V1A subunit of the lysosomal the vacuolar H+ ATPase (v-ATPase).
价 格:¥电议型 号:T11191产 地:中国大陆
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T10046-Benzylaminopurine;6-苄氨基嘌呤6-BAP|||N6-Benzyladenine|||BA|||Benzyladenine;6-苄氨基嘌呤|||6-BAP|||N6-Benzyl
6-Benzylaminopurine (6-BAP), benzyl adenine or BAP is a first-generation synthetic cytokinin that elicits plant growth and development responses, setting blossoms and stimulating fruit richness by stimulating cell division. It is an inhibitor of respiratory kinase in plants, and increases post-harvest life of green vegetables.
价 格:¥电议型 号:T1004产 地:中国大陆