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T41032Lysostaphin;溶葡球菌酶Lysostaphin
Lysostaphin is a potent antistaphylococcal compound that exhibits enzymatic activity through three distinct enzymes: glycylglycine endopeptidase, endo-β-N-acetyl glucosamidase, and N-acetyl muramyl-L-alanine amidase.
价 格:¥电议型 号:T41032产 地:中国大陆
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T40849C20 Ceramide;C20神经酰胺N-Arachidoyl-D-sphingosine;N-Arachidoyl-D-sphingosine
C20 Ceramide (N-Arachidoyl-D-sphingosine) is a 20:0 ceramide found in the brain that crosses the blood-brain barrier to activate microglia and induce depressive-like behavior.
价 格:¥电议型 号:T40849产 地:中国大陆
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T40086Ophiopogonside A;川麦冬苷AOphiopogonside A
Ophiopogonside A is a naturally occurring compound derived from ophiopogon japonicas, with demonstrated anti-cancer activity.
价 格:¥电议型 号:T40086产 地:中国大陆
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T3S1253Cixiophiopogon A;慈溪麦冬皂苷ACixiophiopogon A
Cixiophiopogon A is a natural product from Ophiopogon japonicus.
价 格:¥电议型 号:T3S1253产 地:中国大陆
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T3S1250Ophiogenin 3-O-α-L-rhamnopyranosyl-(1→2)-β-D-glucopyranoside;化合物T3S1250Ophiogenin-3-O-alpha-L-rhaMno
Ophiogenin 3-O-α-L-rhamnopyranosyl-(1→2)-β-D-glucopyranoside (Ophiogenin-3-O-alpha-L-rhaMnopyranosyl-(1->2)-beta-D-glucopyranoside) is a natural product, and has good pharmacological effects on the cardiovascular system.
价 格:¥电议型 号:T3S1250产 地:中国大陆
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T3S1089Phillygenin连翘脂素Epipinoresinol methyl ether|||(+)-Phillygenin|||Phillygenol|||Sylvatesmin|||Forsythig
1. Phillyrin, (+)-Phillygenin (Sylvatesmin), and (-)-phillygenin exert the strongest inhibitory activities on NO production with IC(5) values.
价 格:¥电议型 号:T3S1089产 地:中国大陆
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T39401Sphinganine 1-phosphate;Sphinganine 1-phosphateD-erythro-Dihydrosphingosine 1-phosphate|||Sphinganin
Sphinganine 1-phosphate, also known as D-erythro-Dihydrosphingosine 1-phosphate, is a polar sphingolipid metabolite. It plays a crucial role in regulating various cellular processes including cell migration, differentiation, survival, and complex physiological processes.
价 格:¥电议型 号:T39401产 地:中国大陆
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T3884Neoandrographolide;新穿心莲内酯Neoandrographiside;Neoandrographiside|||新穿心莲内酯
Neoandrographolide (Neoandrographiside) has potent hypolipidemic effect and protects the cardiovascular without significant liver damage.Neoandrographolide has anti-inflammatory effect, might result from inhibition of iNOS and COX-2 expression through inhibiting p38 MAPKs activation.Neoandrographolide as chemosensitizer in S-Jurkat and X chromosome-linked inhibitor of apoptosis protein (XIAP)-overexpressing Jurkat cells, a model for chemoresistance.
价 格:¥电议型 号:T3884产 地:中国大陆
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T38685C12-Sphingosine;C12-SphingosineC12-Sphingosine;C12-Sphingosine
C12-Sphingosine is a short-chain homologue of Sphingosine. It effectively inhibits the activity of serine palmitoyltransferase in primary cultured cerebellar cells.
价 格:¥电议型 号:T38685产 地:中国大陆
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T38452L-threo Lysosphingomyelin (d18:1);L-threo Lysosphingomyelin (d18:1)L-threo-Sphingosylphosphorylcholi
L-threo Lysosphingomyelin (d18:1) (L-threo-Sphingosylphosphorylcholine) is a naturally occurring bioactive sphingolipid. It acts as a potent agonist for S1P receptors, with EC50 values of 19.3, 131.8, and 313.3 nM for hS1P1, hS1P3, and hS1P2, respectively.
价 格:¥电议型 号:T38452产 地:中国大陆
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T38354Lactosylsphingosine (d18:1);Lactosylsphingosine (d18:1)Lactosylsphingosine (d18:1);Lactosylsphingosi
Lactosylsphingosine is a bioactive sphingolipid and a form of lactosylceramide that is lacking the fatty acyl group. Lyso-lactosylceramide (1-50 μM) reduces viability of human neutrophils in a concentration-dependent manner. Unlike lactosylceramide,lactosylsphingosine has no effect on protein synthesis and cell proliferation in cardiomyocytes. Lactosylsphingosine is a precursor in the synthesis of lyso-ganglioside GM3.
价 格:¥电议型 号:T38354产 地:中国大陆
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T38291C24 Phytosphingosine (t18:0/24:0);C24 Phytosphingosine (t18:0/24:0)C24 Phytosphingosine (t18:0/24:0)
C24 Phytosphingosine (t18:0/24:0) is a phytoceramide, which is a family of sphingolipids found in the intestine, kidney, and extracellular spaces of the stratum corneum of the mammalian epidermis. C24 Phytosphingosine (t18:0/24:0) is composed of a phytosphingosine backbone amine-linked to a C24 fatty acid chain. It has been used with other ceramides to create stratum corneum substitutes to study percutaneous penetration and psoriasis in vitro. In a stratum corneum model of healthy skin, the inco
价 格:¥电议型 号:T38291产 地:中国大陆
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T38286C26 Sphingomyelin (d18:1/26:0);C26 Sphingomyelin (d18:1/26:0)C26 Sphingomyelin (d18:1/26:0);C26 Sphi
C26 Sphingomyelin is a sphingolipid that has been found in serum and cell or brain extracts.1,2,3C26 sphingomyelin levels are increased in the serum of patients with hemophagocytic lymphohistiocytosis, an inflammatory condition characterized by excessive immune activation.3C26 sphingomyelin has been used a component of monolayers to study the influence of sphingomyelin acyl chain length on sphingomyelin-sterol interactions.4[Matreya, LLC.]
价 格:¥电议型 号:T38286产 地:中国大陆
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T38262Sphingosine (d14:1);Sphingosine (d14:1)Sphingosine (d14:1)
Sphingosine (d14:1) is a bioactive sphingolipid that has been found in B. mori (silkworm), P. clarkii (crayfish), and A. aurita (jellyfish) extracts. It increases the germination rate of N. rileyi, an entomopathogenic fungus, with an EC50 value of 10.2 nM. Sphingosine (d14:1) inhibits protein kinase C (PKC) in vitro (IC50 = 7.3 mol%) as well as superoxide generation induced by phorbol 12-myristate 13-acetate in neutrophils and reduces growth of CHO cells (IC50s = 19 and 8 μM, respectively).
价 格:¥电议型 号:T38262产 地:中国大陆
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T382141-Deoxysphingosine (m18:1(4E));1-Deoxysphingosine (m18:1(4E))1-Deoxysphingosine (m18:1(4E));1-Deoxys
1-Deoxysphingosine (m18:1(4E)) is an atypical sphingolipid that contains a double bond at the 4E native position and is formed when serine palmitoyltransferase condenses palmitoyl-CoA with alanine instead of serine during sphingolipid synthesis.1,2 Plasma levels of 1-deoxysphingosine (m18:1(4E)) are increased in patients with chronic idiopathic axonal neuropathy (CIAP) and diabetic distal symmetrical polyneuropathy (DSPN).3
价 格:¥电议型 号:T38214产 地:中国大陆
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T382131-β-D-Glucosylsphingadienine (d18:2 (4E,8E));1-β-D-Glucosylsphingadienine (d18:2 (4E,8E))1-β-D-Gluco
1-β-D-Glucosylsphingadienine is a glucosylsphingosine, which are deacetylated lysolipid derivatives of glucosylcerebrosides . They are formed when sphingosines undergo glucosidation by UDP-glucose. Glucosylsphingosines completely reduce neurite outgrowth and induce death of LA-N-2 cells at concentrations of 10 and 50 μM, respectively. They also decrease the activity of glucocerebrosidase in LA-N-2 cells in a dose-dependent manner. Glucosylsphingosine levels are elevated in patients with Gaucher&
价 格:¥电议型 号:T38213产 地:中国大陆
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T38193Lβ-Endorphin (1-27) (human) acetate;化合物β-Endorphin (1-27) (human) acetateβ-Endorphin (1-27) (human) a
β-Endorphin (1-27) (human) acetate, existing in the hypophysis cerebri and hypothalamus, exhibits antinociception activity. β-Endorphin (1-27) (human) acetate is an agonist of opioid receptor, showing preferred affinity for μ-opioid receptor and δ-opioid
价 格:¥电议型 号:T38193L产 地:中国大陆
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T38193β-Endorphin (1-27) (human) (trifluoroacetate salt);β-Endorphin (1-27) (human) (trifluoroacetate salt
β-Endorphin (1-27) is an endogenous peptide that binds to μ-, δ-, and κ-opioid receptors (Kis = 5.31, 6.17, and 39.82 nM, respectively, in COS-1 cells expressing rat receptors). It binds to rat and mouse brain membrane preparations (IC50s = 1.1 and 5.7 nM, respectively) and induces chemotaxis of human monocytes in vitro when used at a concentration of 1 nM. Intracerebroventricular administration of β-endorphin (1-27) increases the latency to tail withdrawal in response to thermal stimulation in
价 格:¥电议型 号:T38193产 地:中国大陆
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T38182C17 Sphingomyelin (d18:1/17:0);C17 Sphingomyelin (d18:1/17:0)C17 Sphingomyelin (d18:1/17:0);C17 Sphi
C17 Sphingomyelin is a synthetic derivative of sphingomyelin that has been used as an internal standard for the quantification of sphingomyelin.
价 格:¥电议型 号:T38182产 地:中国大陆
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T38000Lysosphingomyelin (d18:1);Lysosphingomyelin (d18:1)Lysosphingomyelin (d18:1)
Sphingomyelins are complex membrane lipids composed of phosphorylcholine, sphingosine, and an acylated group, such as a fatty acid. Lysosphingomyelin is a naturally-occurring lipid which is produced by the removal of the acylated group of sphingomyelin by a deacylase. Lysosphingomyelin may, in turn, serve as a substrate for autotaxin, which removes choline to produce sphingosine-1-phosphate. The receptors and signaling pathways that are activated by lyso-sphingosine are diverse and vary between
价 格:¥电议型 号:T38000产 地:中国大陆