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T63295AT2R antagonist 1;化合物 AT2R antagonist 1AT2R antagonist 1
AT2R antagonist 1 is a highly selective and potent AT2R (angiotensin II AT2 receptor) ligand.AT2R antagonist 1 has a high affinity for AT2R affinity (Ki: 29 nM).AT2R antagonist 1 inhibits common drug metabolizing CYP enzymes and has high stability in human, rat, and mouse liver microsomes.AT2R antagonist 1 has a high affinity for AT2R affinity (Ki: 29 nM).AT2R antagonist 1 has a high affinity for AT2R affinity (Ki: 29 nM). It has high stability in human, rat and mouse liver microsomes.
价 格:¥电议型 号:T63295产 地:中国大陆
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T63277Estrogen receptor antagonist 2;化合物 Estrogen receptor antagonist 2Estrogen receptor antagonist 2
Estrogen receptor antagonist 2 is a selective down-regulator of estrogen receptor. Estrogen (E2) and estrogen alpha receptor (ERα) are important drivers of breast cancer development. estrogen receptor antagonist 2 has research potential for breast cancer disease.
价 格:¥电议型 号:T63277产 地:中国大陆
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T63231LPA5 antagonist 1;化合物 LPA5 antagonist 1LPA5 antagonist 1
LPA5 antagonist 1 is a selective and potent lysophosphatidic acid receptor 5 (LPA5) antagonist with an IC50 value of 32 nM. LPA5 antagonist 1 has high brain permeability and antinociceptive activity and can be used to study inflammatory and neuropathic pain.
价 格:¥电议型 号:T63231产 地:中国大陆
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T63197P2X3 antagonist 36;化合物 P2X3 antagonist 36P2X3 antagonist 36
P2X3 antagonist 36 is a P2X3 antagonist.
价 格:¥电议型 号:T63197产 地:中国大陆
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T63172LPA5 antagonist 2;化合物 LPA5 antagonist 2LPA5 antagonist 2
LPA5 antagonist 2 (compound 65) is a highly water-soluble LPA5 antagonist that significantly reduces nociception.LPA5 antagonist 2 can be used to study inflammatory and neuropathic pain.
价 格:¥电议型 号:T63172产 地:中国大陆
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T63106Estrogen receptor antagonist 4;化合物 Estrogen receptor antagonist 4Estrogen receptor antagonist 4
Estrogen Receptor Antagonist 4 is a potent inhibitor of the estrogen receptor (ER), crucial for regulating cell growth, differentiation, and apoptosis. This compound holds promise for cancer research[1].
价 格:¥电议型 号:T63106产 地:中国大陆
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T63100EP4 receptor antagonist 2;化合物 EP4 receptor antagonist 2EP4 receptor antagonist 2
EP4 receptor antagonist 2 (compound 2-13) is a potent agonist of the EP4 receptor (IC50: 7.8 nM) and has antitumour effects.
价 格:¥电议型 号:T63100产 地:中国大陆
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T63088NOD2 antagonist 1;化合物 NOD2 antagonist 1NOD2 antagonist 1
NOD2 antagonist 1 (compound 32) is an effective and selective NOD2 antagonist (IC50: 5.23μM). NOD2 antagonist 1 in THP-1 cells repress Muramyl DiDP (MDP) -induced IL-8 secretion. NOD2 antagonist 1 in PBMCs cells inhibits MDP-induced elevation of IL-6, IL-10 and TNF-α.
价 格:¥电议型 号:T63088产 地:中国大陆
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T63030AR antagonist 2;化合物 AR antagonist 2AR antagonist 2
AR antagonist 2 (compound 58) is a potent inhibitor of the androgen receptor (AR) (IC50: 0.95 μM).
价 格:¥电议型 号:T63030产 地:中国大陆
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T62953Estrogen receptor antagonist 6;化合物 Estrogen receptor antagonist 6Estrogen receptor antagonist 6
Estrogen receptor antagonist 6 is a potent antagonist of the Estrogen receptor. Estrogen receptor is a ligand-activated transcriptional regulatory protein that interacts with endogenous estrogens and mediates the induction of a variety of biological effects. Compound 166).
价 格:¥电议型 号:T62953产 地:中国大陆
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T62952Estrogen receptor antagonist 5;化合物 Estrogen receptor antagonist 5Estrogen receptor antagonist 5
Estrogen receptor antagonist 5 is a potent antagonist of the Estrogen receptor. Estrogen receptor (Estrogen receptor) is a ligand-activated transcriptional regulatory protein that interacts with endogenous estrogens and mediates the induction of a variety of biological effects. estrogen receptor antagonist 5 has potential for metastatic disease studies.
价 格:¥电议型 号:T62952产 地:中国大陆
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T62946Dopamine D3 receptor antagonist-2;化合物 Dopamine D3 receptor antagonist-2Dopamine D3 receptor antagoni
Dopamine D3 receptor antagonist-2 is a dopamine D3 receptor selective (Ki=2.16 nM) or multi-targeting dual ligand that shows potential effects in CNS disorders.
价 格:¥电议型 号:T62946产 地:中国大陆
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T62944CCR8 antagonist 2;化合物 CCR8 antagonist 2CCR8 antagonist 2
CCR8 antagonist 2 is a potent antagonist of CCR8 that inhibits the activity of CCR8 (C-C Motif chemokine receptor 8), which is predominantly expressed on Treg and Th2 cells, and not on Th1 cells. CCR8 antagonist 2 can be used for the treatment of CCR8-mediated diseases (e.g. cancer and/or neuropathic pain).
价 格:¥电议型 号:T62944产 地:中国大陆
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T62918GPR84 antagonist 3;化合物 GPR84 antagonist 3GPR84 antagonist 3
GPR84 Antagonist 3 (compound 42), a potent inhibitor of the G-protein-coupled receptor 84 (GPR84), exhibits a pIC50 value of 8.28, indicating strong antagonistic activity by inhibiting GTPγS. Additionally, it possesses a favorable pharmacokinetic profile, suitable for further research and development [1].
价 格:¥电议型 号:T62918产 地:中国大陆
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T62858hGPR91 antagonist 3;hGPR91拮抗剂3hGPR91 antagonist 3
hGPR91 antagonist 3 is an orally active, potent, and selective hGPR91 antagonist. hGPR91 antagonist 3 is used to study hypertension, autoimmune diseases, and retinal angiogenesis. hGPR91 antagonist 3 has been shown to be effective in the treatment of hypertension, autoimmune disease, and retinal angiogenesis.
价 格:¥电议型 号:T62858产 地:中国大陆
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T62845NRP1 antagonist 2;化合物 NRP1 antagonist 2NRP1 antagonist 2
NRP1 antagonist 2 (Compound 1) is an NRP1 antagonist.
价 格:¥电议型 号:T62845产 地:中国大陆
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T628435-HT1A antagonist 1;化合物 5-HT1A?antagonist 15-HT1A antagonist 1
5-HT1A antagonist 1 (compound 6f) is a potent and selective 5-HT1Areceptor antagonist (Ki: 35 nM). 5-HT1A antagonist 1 can be used in the study of central nervous system disorders.
价 格:¥电议型 号:T62843产 地:中国大陆
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T62838AR antagonist 4;化合物 AR antagonist 4AR antagonist 4
AR antagonist 4 (Compound 67-b) is an orally active androgen receptor (AR) antagonist that acts on wild-type AR (IC50: 246.6 nM).
价 格:¥电议型 号:T62838产 地:中国大陆
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T62797A2A receptor antagonist 3;化合物 A2A receptor antagonist 3A2A receptor antagonist 3
A2A receptor antagonist 3 (Example 92) is an adenosine A2a receptor antagonist (Ki: 0.4 nM). receptor (Ki: 1467 nM).
价 格:¥电议型 号:T62797产 地:中国大陆
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T62768Mu opioid receptor antagonist 4;化合物 Mu opioid receptor antagonist 4Mu opioid receptor antagonist 4
Mu opioid receptor antagonist 4 (compound 31) is a potent and selective mu opioid receptor (MOR) antagonist that permeates the blood-brain barrier (Ki: 0.38 nM, EC50: 0.38 nM). Mu opioid receptor antagonist 2 can be used to study opioid use disorder (OUD).
价 格:¥电议型 号:T62768产 地:中国大陆