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T15340Fosdagrocorat;化合物 T15340PF-04171327;PF-04171327
Fosdagrocorat is an agonist of the dissociated glucocorticoid receptor.
价 格:¥电议型 号:T15340产 地:中国大陆
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T15273Fedovapagon;非多伐贡VA483|||A106483;VA483|||A106483
Fedovapagon (VA106483) is a selective and potent agonist of the vasopressin V2 receptor (V2R) that inhibits the growth of intersegmental vessels in zebrafish. Fedovapagon can be used to study overactive bladder, nocturia, and painful bladder syndromes.
价 格:¥电议型 号:T15273产 地:中国大陆
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T15267GPR40 agonist 4;化合物 T15267GPR40 agonist 4
GPR40 agonist 4 is a potent free fatty acid agonist of receptor 1 (pEC50: 7.54).
价 格:¥电议型 号:T15267产 地:中国大陆
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T15259Evatanepag;化合物EvatanepagCP-533536 free acid;CP-533536 free acid|||2-[3-[N-(4-叔丁基苄基)-N-(吡啶-3-基磺酰基)氨基甲
Evatanepag (CP-533536 free acid) is an EP2 receptor selective prostaglandin E2 (PGE2) agonist that induces local bone formation with EC50 of 0.3 nM.CP-533536 demonstrated the ability to heal fractures when administered locally as a single dose in rat models of fracture healing.
价 格:¥电议型 号:T15259产 地:中国大陆
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T15238Epoprostenol sodium;化合物 T15238Prostaglandin I2 sodium salt|||Prostacyclin sodium salt|||Flolan;Prost
Epoprostenol sodium is a potent inhibitor of platelet aggregation used in pulmonary hypertension and transplantation.
价 格:¥电议型 号:T15238产 地:中国大陆
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T15196EC23;化合物EC23BASF-46928|||AGN 190205;BASF-46928|||AGN 190205
EC23 (AGN 190205) is a stable synthetic retinoid analogue. It is also induces neuronal differentiation.
价 格:¥电议型 号:T15196产 地:中国大陆
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T15159Dorzagliatin化合物DorzagliatinHMS5552
Dorzagliatin (HMS5552) is a dual-acting glucokinase (GK) activator. It also improves glycaemic control and pancreatic β-cell function in type 2 diabetes.
价 格:¥电议型 号:T15159产 地:中国大陆
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T15134Dipraglurant;化合物 T15134ADX48621;ADX48621
Dipraglurant is a negative allosteric regulator (NAM) of blood-brain barrier transmissible mGluR5 with effective, selective and oral activity, with an IC50 value of 21 nM. Dipraglurant can treat levodopa-induced dyskinesia in Parkinson´s disease (PD-LID).
价 格:¥电议型 号:T15134产 地:中国大陆
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T15133Dinoprost;地诺前列素Prostaglandin F2a|||PGF2α;Prostaglandin F2a|||PGF2α|||地诺前列素
Dinoprost (Prostaglandin F2a) is a naturally occurring prostaglandin. It is used in medicine to induce labor and as an abortifacient.
价 格:¥电议型 号:T15133产 地:中国大陆
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T15048Dagrocorat;化合物 T15048PF-00251802;PF-00251802
Dagrocorat is a novel and dissociated agonist of glucocorticoid receptor.
价 格:¥电议型 号:T15048产 地:中国大陆
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T1502Vildagliptin维格列汀维达列汀|||NVP-LAF 237|||维格列汀|||LAF237
Vildagliptin (LAF237) is a cyanopyrrolidine-based, orally bioavailable inhibitor of dipeptidyl peptidase 4 (DPP-4), with hypoglycemic activity. Vildagliptin´s cyano moiety undergoes hydrolysis and this inactive metabolite is excreted mainly via the urine.
价 格:¥电议型 号:T1502产 地:中国大陆
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T14928Agerafenib hydrochloride;化合物 T14928RXDX-105 hydrochloride|||CEP-32496 (hydrochloride);RXDX-105 hydro
Agerafenib hydrochloride is a highly potent inhibitor of BRAFV600E (Kd: 14 nM).
价 格:¥电议型 号:T14928产 地:中国大陆
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T14899CCR1 antagonist 8;化合物 T14899CCR1 antagonist 8
CCR1 antagonist 8, a third azaindazole series compound, is a CCR1 antagonist (IC50: 1.8 nM in Ca2+ flux assay).
价 格:¥电议型 号:T14899产 地:中国大陆
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T14881CB1 antagonist 2;化合物CB1 antagonist 2AM4113;AM4113
CB1 antagonist 2 (AM4113) is caimabinoid 1 (CB1) antagonist which inhibits CB1 in vivo with an IC50 of 25.5 nM.
价 格:¥电议型 号:T14881产 地:中国大陆
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T14861Camobucol;化合物 T14861AGIX 4207;AGIX 4207
Camobucol is an orally active, anti-inflammatory compound. It also is a phenolic antioxidant with antirheumatic properties.
价 格:¥电议型 号:T14861产 地:中国大陆
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T14775Bragsin2;化合物Bragsin26-methoxy-5-nitro-2-(trifluoromethyl)chromen-4-one|||Bragsin 2;6-methoxy-5-nitro
Bragsin2 (6-methoxy-5-nitro-2-(trifluoromethyl)chromen-4-one) is a hydration-resistant cell penetrant, selective and non-competitive inhibitor of Afr guanine nucleotide exchange factor BRAG2 that inhibits Arf GTPase activation, with an IC50 of 3 μM. Bragsin2 binds at the interface between the pleckstrin homology domain of BRAG2 and the lipid bilayer, leading BRAG2 unable to activate lipidated Arf GTPase.
价 格:¥电议型 号:T14775产 地:中国大陆
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T14774Bragsin1;化合物 T14774Bragsin1
Bragsin1 is a potent and selective and noncompetitive ArfGEF BRAG2 inhibitor, inhibits Arf GTPase activation(IC50 : 3 μM),and with anti-cancer activity.
价 格:¥电议型 号:T14774产 地:中国大陆
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T14522Beaucage reagent;化合物Beaucage reagentBeaucage reagent
Beaucage reagent, which is found to be effective in causing DNA cleavage.
价 格:¥电议型 号:T14522产 地:中国大陆
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T1452Axitinib;阿昔替尼AG-013736;AG-013736|||阿昔替尼|||阿西替尼
Axitinib (AG-013736) is an orally bioavailable tyrosine kinase inhibitor with IC50s of 0.1, 0.2, 0.1-0.3, 1.7, 1.6 nM for VEGFR1, VEGFR2, VEGFR3, c-kit, and PDGFRβ, respectively.
价 格:¥电议型 号:T1452产 地:中国大陆
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T1445Agomelatine;阿戈美拉汀Thymanax|||S-20098|||Valdoxan;Thymanax|||S-20098|||Valdoxan|||阿戈美拉汀
Agomelatine (Valdoxan) is structurally closely related to melatonin. Agomelatine is a potent agonist at melatonin receptors and an antagonist at serotonin-2C (5-HT2C) receptors, tested in an animal model of depression.
价 格:¥电议型 号:T1445产 地:中国大陆