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  • T14374AZD2906；化合物 T14374AZD2906

    AZD2906, a selective glucocorticoid receptor (GR) agonist, demonstrates inhibitory concentrations (IC50s) of 2.2 nM in human GR, 0.3 nM in rat peripheral blood mononuclear cells (PBMC), 41.6 nM in human whole blood, and 7.5 nM in rat whole blood, respectively[1]. Additionally, it induces an increase in micronucleated immature erythrocytes within rat bone marrow.

    价 格：￥电议型 号：T14374产 地：中国大陆

  • T14373AZD2423；化合物 T14373AZD2423

    AZD2423 is a potent, selective, orally bioavailable, and non-competitive CCR2 chemokine receptor negative allosteric modulator and it has an IC50 of 1.2 nM for CCR2 Ca2+ flux [1][2][3].

    价 格：￥电议型 号：T14373产 地：中国大陆

  • T14372AZD1979；化合物 T14372AZD1979

    AZD1979 is an antagonist of Melanin-concentrating hormone receptor 1 (MCHr1) (IC50: 12 nM).

    价 格：￥电议型 号：T14372产 地：中国大陆

  • T14371Barasertib；巴拉塞替AZD1152；巴拉塞替|||AZD1152

    AZD1152 is a pro-drug of Barasertib (AZD1152)-hQPA. Which is a highly selective Aurora B inhibitor with IC50 of 0.37 nM in a cell-free assay.

    价 格：￥电议型 号：T14371产 地：中国大陆

  • T14370AZD0424；化合物 T14370AZD0424

    AZD0424, an orally active compound characterized as a dual selective Src/Abl kinase inhibitor, exhibits potential antineoplastic activity[1] and promotes apoptosis and cell cycle arrest in lymphoma cells[2].

    价 格：￥电议型 号：T14370产 地：中国大陆

  • T1437D-Panthenol；D-泛醇D-Pantothenyl alcohol|||Ilopan|||Dexpanthenol|||Pantothenol；D-泛醇|||D-Pantothenyl alc

    D-Panthenol (D-Pantothenyl alcohol) is an alcoholic analogue of D-pantothenic acid and cholinergic agent. D-Panthenol acts as a precursor of coenzyme A necessary for acetylation reactions and is involved in the synthesis of acetylcholine. Although the exact mechanism of the actions of D-Panthenol is unclear, it may enhance the effect of acetylcholine. D-Panthenol acts on the gastrointestinal tract and increases lower intestinal motility. It is also applied topically to the skin to relieve itchin

    价 格：￥电议型 号：T1437产 地：中国大陆

  • T14369AZD-0284；化合物AZD-0284AZD-0284

    AZD-0284 is an inverse agonist of the nuclear receptor RORγ. In development for the treatment of plaque psoriasis vulgaris and respiratory tract disorders[1].

    价 格：￥电议型 号：T14369产 地：中国大陆

  • T14368Azadirachtin B；印楝素 BAzadirachtin B

    Azadirachtin B, a limonoid derived from the seed kernels of Azadirachta indica, exhibits a broad spectrum of biochemical activities, including insecticidal, nematocidal, anticancer, anti-inflammatory, antiviral, and osteogenic effects. It is effective against the Epstein-Barr virus early antigen (EBV-EA), enhances alkaline phosphatase (ALP) activity, and promotes osteoblast differentiation[1][2][3].

    价 格：￥电议型 号：T14368产 地：中国大陆

  • T14367AZ1495；化合物AZ1495AZ1495

    AZ1495 is an oral active inhibitor of Interleukin-1 receptor associated kinase 4 (IRAK4), with IC50 values of 5 nM and 23 nM for IRAK4 and IRAK1, respectively. Which Shows activity in treatment of mutant MYD88L265P diffuse large B-cell lymphoma (DLBCL).

    价 格：￥电议型 号：T14367产 地：中国大陆

  • T14366AZ10606120 dihydrochloride；化合物AZ10606120 dihydrochlorideAZ10606120 dihydrochloride

    AZ10606120 dihydrochloride is a selectable, potent, high-affinity receptor antagonist with K D values of 1.4 and 19 nM at human and rat P2X 7 receptors, respectively. AZ10606120 dihydrochloride inhibits tumor growth and has anti-angiogenic activity. AZ 10606120 acts as a negative allosteric modulator when bound to a site coupled to the ATP binding site.

    价 格：￥电议型 号：T14366产 地：中国大陆

  • T14365AZ PFKFB3 26；化合物AZ PFKFB3 26AZ PFKFB3 26

    AZ PFKFB3 26 is an effective and selective PFKFB3 inhibitor with an IC50 of 23 nM. The IC50s for PFKFB1 and PFKFB2 are 2.06 and 0.384 μM, respectively.

    价 格：￥电议型 号：T14365产 地：中国大陆

  • T14364AZ-Dyrk1B-33；化合物T143643-(2-Methyl-4-pyrimidinyl)-1-(phenylmethyl)-1H-pyrrolo[2,3-c]pyridine；3-(2-Met

    AZ-Dyrk1B-33 (3-(2-Methyl-4-pyrimidinyl)-1-(phenylmethyl)-1H-pyrrolo[2,3-c]pyridine) is a potent and selective Dyrk1B kinase inhibitor with an IC50 of 7 nM.

    价 格：￥电议型 号：T14364产 地：中国大陆

  • T14363AZ-23；化合物AZ-23AZ 23|||AZ23；AZ 23|||AZ23

    AZ-23 is an inhibitor of ATP-competitive and Trk kinase A/B/C. For TrkA, TrkB, FGFR1, Flt3, Ret, MuSk, Lck, the IC50s values are 2 nM, 8 nM, 24 nM, 52 nM, 55 nM, 84 nM, 99 nM, respectively.

    价 格：￥电议型 号：T14363产 地：中国大陆

  • T14362LAY 9944 dihydrochloride；化合物AY 9944 盐酸盐AY 9944 dihydrochloride

    AY 9944 dihydrochloride is a intermediate.

    价 格：￥电议型 号：T14362L产 地：中国大陆

  • T14362AY 9944；化合物AY 9944AY 9944

    AY 9944 is a specific cholesterol biosynthesis inhibitor. AY 9944 inhibits the 7-dehydro cholesterol Δ7-reductase (DHCR7) enzyme (IC50=13 nM). At high doses, AY 9944 inhibits also in cultured embryos sterol Δ7-Δ8 isomerase, which causes the accumulation of cholest-8-en-3β-ol[1][2][3]. AY 9944 causes hypocholesterolemia and accumulation of 7DHC.

    价 格：￥电议型 号：T14362产 地：中国大陆

  • T14361Axomadol；阿索马多EN3324；阿索马多|||EN3324

    Axomadol (EN3324) is a centrally active analgesic compound. It has opioid agonistic properties and inhibitory effects on the reuptake of monoamines.

    价 格：￥电议型 号：T14361产 地：中国大陆

  • T14360AX-15836；化合物AX-15836AX-15836

    AX-15836 is an inhibitor of ERK5 (IC50 : 8 nM).

    价 格：￥电议型 号：T14360产 地：中国大陆

  • T14364-Aminohippuric Acid对氨基马尿酸p-Aminohippuric acid|||对氨基马尿酸

    4-Aminohippuric Acid is the glycine amide of 4-aminobenzoic acid. Its sodium salt is used as a diagnostic aid to measure effective renal plasma flow (ERPF) and excretory capacity.

    价 格：￥电议型 号：T1436产 地：中国大陆

  • T14359AVX 13616；化合物 T14359AVX 13616

    AVX 13616, Avexa´s leading antibacterial candidate, demonstrates significant in vivo antibacterial efficacy, especially against drug-resistant Staphylococcus pathogens, with an IC50 value of 2-4 ?g/ml (MICs) and is targeted as an antibacterial agent. Comparable in activity to mupirocin within a nasal decolonization model, AVX13616 necessitated only a single application for effectiveness. This compound, alongside others, exhibited broad-spectrum antibacterial action, achieving MICs of 2-4 m

    价 格：￥电议型 号：T14359产 地：中国大陆

  • T14358Avoralstat；AVORALSTATBCX4161；BCX4161

    Avoralstat (BCX4161) is an oral plasma kallikrein (PKK) inhibitor. Which is used for the treatment of hereditary angioedema.

    价 格：￥电议型 号：T14358产 地：中国大陆

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