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T110951Compound F0447-0245;化合物 F0447-0245Compound F0447-0245
Antitubercular agent-33 is a 2-aminothiazole derivative with potent anti-tubercular activity against Mycobacterium tuberculosis ( Mtb ) [1].
价 格:¥电议型 号:T110951产 地:中国大陆
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T11090L1Aldoxorubicin hydrochloride;化合物Aldoxorubicin盐酸盐Aldoxorubicin hydrochloride (1361644-26-9 Free base);
Aldoxorubicin hydrochloride is an albumin-binding prodrug of Doxorubicin, a DNA topoisomerase II inhibitor. Aldoxorubicin hydrochloride is released from albumin under acidic conditions. Aldoxorubicin hydrochloride exhibits potent antitumor activities in various cancer cell lines and in murine tumor models.
价 格:¥电议型 号:T11090L1产 地:中国大陆
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T11052LDisitertide acetate;地司特泰醋酸盐P144 acetate|||Disitertide acetate(272105-42-7 Free base);P144 acetate|||
Disitertide acetate (P144 acetate) is a peptidic transforming growth factor-beta 1 (TGF-β1) inhibitor specifically designed to block the interaction with its receptor. Disitertide acetate is also a PI3K inhibitor and an apoptosis inducer.
价 格:¥电议型 号:T11052L产 地:中国大陆
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T11052Disitertide;化合物 T11052P144;P144
Disitertide (P144) is an inhibitor of TGF-β1.
价 格:¥电议型 号:T11052产 地:中国大陆
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T11044Dihydromunduletone化合物DihydromunduletoneDHM
Dihydromunduletone (DHM) is an adhesion G protein-coupled receptor (aGPCR) antagonist that acts as a chemical probe for the inhibition of GPR56 and GPR114/ADGRG5, which have similar tethered agonists.
价 格:¥电议型 号:T11044产 地:中国大陆
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T10975DC44SMe;化合物 T10975DC44SMe
The IC50 of DC44SMe for Ramos, Namalwa and HL60 / s cancer cells was 2.0 nM, 2.8 nM and 1.9 nM, respectively. DC44SMe can be used for targeted treatment of cancer. DC44SMe is a phosphate prodrug of DC44 and can be used in the synthesis of antibody-drug conjugates (ADC).
价 格:¥电议型 号:T10975产 地:中国大陆
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T10944D13-9001;化合物 T10944D13-9001
The KD values of D13-9001 in Escherichia coli and Pseudomonas aeruginosa were 1.15μM and 3.57μM, respectively. D13-9001 has antibiotic activity. It is an effective AcrB (AcrAB-TolC efflux pump subunit) and MexB (MexAB-OprM efflux pump subunit) inhibitor.
价 格:¥电议型 号:T10944产 地:中国大陆
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T10937LD-JNKI-1 acetate;化合物D-JNKI-1 acetateD-JNKI-1 acetate(1445179-97-4 Free base)|||AM-111 acetate;D-JNKI
D-JNKI-1 acetate (AM-111 acetate) is a highly potent and cell-permeable peptide inhibitor of JNK.
价 格:¥电议型 号:T10937L产 地:中国大陆
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T10883LCRA-026440 hydrochloride;化合物CRA-026440盐酸盐CRA-026440 hydrochloride(847460-34-8 Free base);CRA-026440
CRA-026440 hydrochloride is a potent and broad-spectrum HDAC inhibitor. CRA-026440 hydrochloride exhibits Ki values against recombinant HDAC isoenzymes HDAC1, HDAC2, HDAC3, HDAC6, HDAC8, and HDAC10 are 4 nM, 14 nM, 11 nM, 15 nM, 7 nM, and 20 nM, respectively. CRA-026440 hydrochloride exhibits antitumor and antiangiogenic activities.
价 格:¥电议型 号:T10883L产 地:中国大陆
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T10883CRA-026440;化合物CRA-026440PCI-34051;PCI-34051
CRA-026440(PCI-34051) is a highly potent HDAC inhibitor with inhibitory effects on HDAC1, HDAC2, HDAC3, HDAC6, HDAC8 and HDAC10 with Ki values of 4,14,11,15,7 and 20 nM, respectively. CRA-026440 has anti-tumor and anti-angiogenic activity and can be used to study colon cancer.
价 格:¥电议型 号:T10883产 地:中国大陆
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T10844CMI-392;化合物 T10844CMI-392
CMI-392 is a dual 5-lipoxygenase inhibitor and platelet-activating factor (PAF) receptor antagonist (IC50s: 100 and 10 nM).
价 格:¥电议型 号:T10844产 地:中国大陆
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T10744LSEL120-34A HCl;化合物SEL120-34A HClSEL120-34A HCl
SEL120-34A HCl is a selective, orally available and ATP-competitive inhibitor of CDK8(CDK8/CycC and CDK19/CycC with IC50s of 4.4 nM and 10.4 nM , respectively), with antitumor activity.
价 格:¥电议型 号:T10744L产 地:中国大陆
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T10744SEL120-34A;化合物SEL120-34ASEL120-34A
SEL120-34A is a selective and ATP-competitive inhibitor of CDK8 with IC50s of 4.4 nM, 10.4 nM and 1070 nM for CDK8/CycC, CDK19/CycC and CDK9/cycT. SEL120-34A possesses antitumor activity.
价 格:¥电议型 号:T10744产 地:中国大陆
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T10693CB-6644;化合物CB-6644CB-6644
CB-6644 is a selective inhibitor of the RUVBL1/2 complex and blocks the ATPase activity of RUVBL1/2 (IC50 = 15 nM).
价 格:¥电议型 号:T10693产 地:中国大陆
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T10644c-Fms-IN-10;化合物 T10644c-Fms-IN-10
c-Fms-IN-10 is the derivative of thieno [3,2-d] pyrimidine, a kinase inhibitor of FMS (Colony-stimulating factor-1 receptor, CSF-1R; IC50: 2 nM) with anti-tumor activity.
价 格:¥电议型 号:T10644产 地:中国大陆
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T10615BRL44385;化合物 T10615BRL44385
BRL44385 is an effective and selective inhibitor of the replication of HSV-1 and HSV2, Epstein-Barr virus (EBV), and varicella-zoster virus (VZV).
价 格:¥电议型 号:T10615产 地:中国大陆
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T10613BRL 37344 sodium;化合物 T10613BRL 37344A;BRL 37344A
BRL 37344 sodium is a specific agonist of the β3-adrenergic receptor. The treatment of BRL 37344 sodium significantly lowers the bodyweight of obese mice.
价 格:¥电议型 号:T10613产 地:中国大陆
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T10569BMS-654457;化合物 T10569BMS-654457
BMS-654457 is a small-molecule, reversible inhibitor of factor XIa (FXIa; Kis: 0.2 and 0.42 nM for human and rabbit FXIa).
价 格:¥电议型 号:T10569产 地:中国大陆
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T10544Bimatoprost D5;化合物 T10544AGN 192024 D5;AGN 192024 D5
Bimatoprost (AGN 192024) D5 is a deuterium-labeled Bimatoprost. Bimatoprost is a topical hypotensive agent frequently used for treating glaucoma and ocular hypertension.
价 格:¥电议型 号:T10544产 地:中国大陆
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T10491LGalidesivir hydrochloride;化合物 T10491LBCX 4430 hydrochloride|||Immucillin-A hydrochloride;BCX 4430 hy
Galidesivir hydrochloride is an inhibitor of viral RNA-dependent RNA polymerase (RdRp). It inhibits SARS-CoV-2 by tightly binding to its RdRp.
价 格:¥电议型 号:T10491L产 地:中国大陆