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T10571BMS-901715;化合物 T10571BMS-901715
BMS-901715 is an effective and selective inhibitor of adapter protein-2 associated kinase 1 (AAK1; IC50: 3.3 nM).
价 格:¥电议型 号:T10571产 地:中国大陆
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T10570Fostemsavir Tris;化合物Fostemsavir TrisBMS-663068 Tris;BMS-663068 Tris
Fostemsavir Tris (BMS-663068 Tris) is the prodrug of BMS-626529,is a oral, safe and effective inhibitor of HIV-1 attachment. It inhibits human immunodeficiency virus type 1 (HIV-1) infection by binding to gp120 and interfering with the attachment of virus to CD4+ T-cells.
价 格:¥电议型 号:T10570产 地:中国大陆
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T10569BMS-654457;化合物 T10569BMS-654457
BMS-654457 is a small-molecule, reversible inhibitor of factor XIa (FXIa; Kis: 0.2 and 0.42 nM for human and rabbit FXIa).
价 格:¥电议型 号:T10569产 地:中国大陆
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T10568BMS-470539 dihydrochloride;化合物 T10568BMS-470539 dihydrochloride
BMS-470539 dihydrochloride is a highly potent and selective agonist of the melanocortin-1 receptor (MC-1R; IC50: 120 nM; EC50: 28 nM) with anti-inflammatory properties. It does not activate MC-3R and is a very weak partial agonist at MC-4R and MC-5R.
价 格:¥电议型 号:T10568产 地:中国大陆
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T10567BMS-214662;化合物 T10567BMS-214662
BMS-214662 is a potent and selective farnesyl transferase inhibitor that induces mitochondrial apoptosis in primitive CD34+ chronic myeloid leukemia (CML) stem cells/progenitors, and has the ability to selectively target CML stem cells/progenitors with antitumor activity.
价 格:¥电议型 号:T10567产 地:中国大陆
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T10566BMS-191095;化合物BMS-191095BMS-191095
BMS-191095 is mitochondrial ATP-sensitive potassium (mitoKATP) channel activator.
价 格:¥电议型 号:T10566产 地:中国大陆
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T10565BMS-1001 hydrochloride;化合物BMS-1001 hydrochlorideBMS-1001 hydrochloride
BMS-1001 hydrochloride is an orally active inhibitor of human PD-1/PD-L1 immune checkpoint with low-toxicity in cells.BMS-1001 alleviates the inhibitory effect of the soluble PD-L1 on the T-cell receptor-mediated activation of T-lymphocytes. BMS-1001 is capable of alleviating the PD-1/PD-L1 immune checkpoint-mediated exhaustion of Jurkat T-lymphocytes.
价 格:¥电议型 号:T10565产 地:中国大陆
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T10541Bicyclomycin benzoate;化合物 T10541FR2054;FR2054|||CS-6253
Bicyclomycin benzoate, an antibiotic, exhibits activity against a broad spectrum of Gram-negative/Gram-positive bacteria.
价 格:¥电议型 号:T10541产 地:中国大陆
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T1051Retinoic acid;维生素A酸Vitamin A acid|||ATRA|||all-trans-Retinoic acid|||Tretinoin;维生素A酸|||Vitamin A aci
Retinoic acid (Tretinoin), a metabolite of vitamin A, is a natural agonist of the retinoic acid receptor RAR and inhibits RARα/β/γ (IC50=14 nM). Retinoic acid induces cellular differentiation, reduces cellular proliferation, and inhibits tumorigenesis.
价 格:¥电议型 号:T1051产 地:中国大陆
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T10493Beclabuvir;贝拉布韦BMS-791325;BMS-791325
Beclabuvir (BMS-791325) is a potent NS5A replication complex inhibitor that inhibits the activity of the NS5B protein expressed by HCV genotypes 1, 2, 4, and 5 and is used in the study of HCV infection.
价 格:¥电议型 号:T10493产 地:中国大陆
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T10465Atuveciclib S-Enantiomer;化合物 T10465BAY-1143572 S-Enantiomer;BAY-1143572 S-Enantiomer
Atuveciclib S-Enantiomer (BAY-1143572 S-Enantiomer) is the (S)-enantiomer of BAY-1143572. Atuveciclib S-Enantiomer is a potent and selective CDK9 inhibitor, which inhibits CDK9 / CycT1 with an IC 50 of 16 nM.
价 格:¥电议型 号:T10465产 地:中国大陆
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T10439Azelnidipine D7;化合物 T10439CS-905 D7;CS-905 D7
Azelnidipine D7 is a deuterium-labeled Azelnidipine. Azelnidipine is an L-type calcium channel blocker.
价 格:¥电议型 号:T10439产 地:中国大陆
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T10376ARS-1630;化合物ARS-1630ARS-1630
ARS-1630 is a mutant K-ras G12C inhibitor. It is a less active enantiomer of ARS-1620.
价 格:¥电议型 号:T10376产 地:中国大陆
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T10375ARS-1323;化合物ARS-1323ARS-1323
ARS-1323 is the racemate of ARS-1620 and a mutant K-ras G12C inhibitor.
价 格:¥电议型 号:T10375产 地:中国大陆
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T10374ARS-1323-alkyne;化合物ARS-1323-alkyneARS-1323-alkyne
ARS-1323-alkyne is a switch-II pocket (S-IIP) inhibitor and a conformational specific chemical reporter of KRASG12C nucleotide state in living cells.
价 格:¥电议型 号:T10374产 地:中国大陆
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T1037Doripenem monohydrate;多尼培南(一水合物)S 4661 monohydrate|||Doripenem Hydrate|||S-4661;多尼培南(一水合物)|||S 4661
Doripenem monohydrate (S 4661 monohydrate) is a broad-spectrum injectable antibiotic, used for Gram-positive, Gram-negative and anaerobic pathogens.
价 格:¥电议型 号:T1037产 地:中国大陆
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T10363Arazine;化合物ArazineN-Acetyl-S-farnesyl-L-cysteine;N-Acetyl-S-farnesyl-L-cysteine
Arazine (N-Acetyl-S-farnesyl-L-cysteine) can be a a substrate for isoprenylcysteine methyltransferase by competing with prenylated G protein or its receptors site. Arazine is a cell-permeable modulator of G protein and GPCR signaling.
价 格:¥电议型 号:T10363产 地:中国大陆
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T10297AMG 487 (S-enantiomer);化合物 T10297AMG 487 (S-enantiomer)
AMG 487 S-enantiomer is the S enantiomer of AMG 487. AMG 487 is an CXCR3 antagonist.
价 格:¥电议型 号:T10297产 地:中国大陆
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T10267Agomelatine (L(+)-Tartaric acid);阿戈美拉汀 L(+)-酒石酸S-20098 L(+)-Tartaric acid;阿戈美拉汀 L(+)-酒石酸|||S-20098 L
Agomelatine (S-20098) L(+)-Tartaric acid is a specific agonist of MT1 and MT2 receptors (Kis: 0.1, 0.06, 0.12, and 0.27 nM for CHO-hMT1, HEK-hMT1, CHO-hMT2, and HEK-hMT2). It also is a selective 5-HT2C receptor antagonist (pKis: 6.4 and 6.2 at native (porcine) and cloned (human) 5-HT2C receptors).
价 格:¥电议型 号:T10267产 地:中国大陆
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T10266Agomelatine-d6;化合物 T10266Agomelatine D6|||S-20098 D6;Agomelatine D6|||S-20098 D6
Agomelatine D6 (S-20098 D6) is a deuterium-labeled Agomelatine. Agomelatine is a specific agonist of MT1 and MT2 receptors.
价 格:¥电议型 号:T10266产 地:中国大陆