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  • T14319Aripiprazole Lauroxil；月桂酰阿立派唑Aripiprazole Lauroxil

    Aripiprazole lauroxil, the N-acyloxymethyl prodrug form of aripiprazole, a long-acting injectable (LAI) antipsychotic. Aripiprazole lauroxil is cleaved by esterases in vivo to N-hydroxymethyl aripiprazole (lauric acid), which is then cleaved to aripiprazole, which is non-toxic.

    价 格：￥电议型 号：T14319产 地：中国大陆

  • T14318ARCC-4；化合物 T14318ARCC-4

    ARCC-4 is an enzalutamide-based von Hippel-Lindau (VHL)-recruiting AR PROTAC and outperforms enzalutamide and it is a low-nanomolar androgen receptor (AR) degrader based on PROTAC, with a DC50 of 5 nM. ARCC-4 effectively degrades clinically relevant AR mutants associated with antiandrogen therapy[1].

    价 格：￥电议型 号：T14318产 地：中国大陆

  • T14317ar-Turmerone；化合物 T14317(+)-ar-Turmerone；(+)-ar-Turmerone

    ar-Turmerone ((+)-ar-Turmerone) is a major bioactive compound of the herb Curcuma longa with anti-tumorigenesis and anti-inflammatory activities[1][2][3]. ar-Turmerone ((+)-ar-Turmerone) exerts positive modulation on murine DCs, induces NSC proliferation. And it constitutes a promising therapeutic agent for various neurologic disorders[4][5]. ar-turmerone ((+)-ar-Turmerone) activates apoptotic protein in human lymphoma U937 cells[3].

    价 格：￥电议型 号：T14317产 地：中国大陆

  • T14316AR-C155858；化合物AR-C155858AR-C155858

    AR-C155858 is an inhibitor of monocarboxylate transporter MCT1 and MCT2 (Kis: 2.3 nM and 10 nM).

    价 格：￥电议型 号：T14316产 地：中国大陆

  • T14315AR-9281；化合物AR-9281APAU；APAU

    AR-9281 (APAU) is a potent and selective inhibitor of soluble epoxide hydrolase (s-EH) potentially for the treatment of hypertension and type 2 diabetes

    价 格：￥电议型 号：T14315产 地：中国大陆

  • T14314Apronal；丙戊酰脲Apronalide|||Allylisopropylacetylurea；Apronalide|||Allylisopropylacetylurea|||丙戊酰脲

    Apronal (Apronalide) has the hypnotic and sedative capacity and can be used for studies about neuropsychiatry disorders.

    价 格：￥电议型 号：T14314产 地：中国大陆

  • T14313Apricitabine；阿立他滨AVX754|||SPD754；AVX754|||SPD754

    Apricitabine (SPD754) is a highly selective and orally active HIV-1 reverse transcriptase inhibitor (Ki=0.08 μM), the (-) enantiomer of 2′-deoxy-3′-oxy-4′-thiocytidine (dOTC) . Apricitabine inhibits DNA polymerase α, β and γ with Ki values of 300 μM, 12 μM and 112.25 μM, respectively. Apricitabine has shown good antiretroviral therapeutic efficacy in antiretroviral HIV-infected patients, with good tolerability and low selective resistance.

    价 格：￥电议型 号：T14313产 地：中国大陆

  • T14312Apratastat化合物 T14312Apratastat

    Apratastat is an orally active, potent, and reversible dual inhibitor of tumor necrosis factor-α converting enzyme (TACE) and matrix metalloproteinases (MMPs) and it also can potently inhibit the release of TNF-α in vitro, ex vivo, and in vivo with IC50s of 144 ng/mL in vitro and 81.7 ng/mL ex vivo, respectively[1].

    价 格：￥电议型 号：T14312产 地：中国大陆

  • T14311APN-?NH2；化合物 T14311APN-?NH2

    APN- NH2 is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].

    价 格：￥电议型 号：T14311产 地：中国大陆

  • T14310APN-C3-PEG4-azide；化合物 T14310APN-C3-PEG4-azide

    APN-C3-PEG4-azide is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

    价 格：￥电议型 号：T14310产 地：中国大陆

  • T1431Khellin；呋喃并色酮Amicardine|||Methafrone|||Visammin；凯林|||Amicardine|||Methafrone|||Visammin

    Khellin (Methafrone) is a vasodilator that also has bronchodilatory action.

    价 格：￥电议型 号：T1431产 地：中国大陆

  • T14309APN-C3-PEG4-alkyne；化合物 T14309APN-C3-PEG4-alkyne

    APN-C3-PEG4-alkyne is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

    价 格：￥电议型 号：T14309产 地：中国大陆

  • T14308APN-C3-NH-Boc；化合物 T14308tert-Butyl 3-(4-(2-cyanoethynyl)phenylcarbamoyl)propylcarbamate；tert-Butyl 3

    APN-C3-NH-Boc is a alkyl/ether-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

    价 格：￥电议型 号：T14308产 地：中国大陆

  • T14307Aplaviroc；阿拉韦洛GSK 873140|||ONO-4128|||GW 873140|||AK 602；GSK 873140|||ONO-4128|||GW 873140|||AK 602

    Aplaviroc (AK 602) is a novel and highly potent CCR5 antagonist with antiviral activity that inhibits HIV-1Ba-L, HIV-1JRFL, and HIV-1MOKW and can be used in the study of human immunodeficiency virus infection.

    价 格：￥电议型 号：T14307产 地：中国大陆

  • T14306Apimostinel；化合物 T14306AGN-241660|||NRX-1074；AGN-241660|||NRX-1074

    Apimostinel (NRX-1074; AGN-241660) is a partial agonist of NMDA receptor.

    价 格：￥电议型 号：T14306产 地：中国大陆

  • T14305Apicidin；化合物 ApicidinOSI 2040；OSI 2040

    Apicidin (OSI 2040) is a histone deacetylase (HDAC) inhibitor with antiparasitic activity and antiproliferative activity.Apicidin attenuates memory deficits, inhibits cell growth and proliferation, and induces apoptosis and autophagy by decreasing Abeta load in APP/PS1 mice, and can be used to study leukemia.

    价 格：￥电议型 号：T14305产 地：中国大陆

  • T14304Aphidicolin；阿非迪霉素Aphidicolin

    Aphidicolin, an antibiotic derived from the mold Cephalosporium aphidicola, is a potent inhibitor of DNA (deoxyribonucleic acid) synthesis, effectively hindering the proliferation of herpes simplex virus[2]. It targets DNA polymerase α and δ, disrupting mitotic cell division by affecting DNA polymerase activity[1]. Additionally, aphidicolin enhances apoptosis when combined with arabinosyl nucleosides in a human promyelocytic leukemia cell line[3].

    价 格：￥电议型 号：T14304产 地：中国大陆

  • T14303Alrizomadlin；化合物AlrizomadlinAPG-115|||AA-115；APG-115|||AA-115

    Alrizomadlin (APG-115) is an orally active inhibitor of MDM2 with IC50 of 3.8 nM and Ki of 1 nM, respectively[1]. Alrizomadlin blocks the interaction of MDM2 and p53 and induces cell-cycle arrest and apoptosis in a p53-dependent manner.

    价 格：￥电议型 号：T14303产 地：中国大陆

  • T14302Olorinab；化合物OlorinabAPD 371；APD 371

    Olorinab (APD 371) (APD 371) is a highly potent, selective and fully efficacious cannabinoid receptor type 2 (CB2) agonist. With an EC50 of 6.2 nM for hCB2.

    价 格：￥电议型 号：T14302产 地：中国大陆

  • T14301Apararenone；化合物ApararenoneMT-3995；MT-3995

    Apararenone (MT-3995) is a receptor antagonist of mineralocorticoid receptor which can be used to treat non-alcoholic steatohepatitis and diabetic nephropathy.

    价 格：￥电议型 号：T14301产 地：中国大陆

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