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T1430Betamipron；倍他米隆CS-443|||N-Benzoyl-β-alanine；CS-443|||N-Benzoyl-β-alanine|||倍他米隆
Betamipron (CS-443) is used combination with panipenem to prevent nephrotoxicity and inhibit panipenem uptake into the renal tubule.
价 格：￥电议型 号：T1430产 地：中国大陆
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T14243Amino-PEG5-amine；化合物 T14243Amino-PEG5-amine
Amino-PEG5-amine, a PEG-based linker containing 5 units, is utilized in PROTAC synthesis.
价 格：￥电议型 号：T14243产 地：中国大陆
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T14176Aleglitazar；阿格列扎RO0728804|||R1439；RO0728804|||R1439
Aleglitazar (R1439) (R1439) is a potent dual PPARα/γ agonist, with IC50s of 38 nM and 19 nM for human PPARa and PPARγ, respectively. Aleglitazar can be used for the research of type II diabetes.
价 格：￥电议型 号：T14176产 地：中国大陆
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T14143AGN 194310；化合物 T14143VTP-194310；VTP-194310
AGN 194310 (VTP-194310) is retinioic acid receptors (RARs) pan-antagonist. The Kd values of 3 nM, 2 nM, 5 nM for RARα, RARβ, RARγ, respectively[1][2].
价 格：￥电议型 号：T14143产 地：中国大陆
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T14136AG-024322；化合物 T14136AG-024322
AG-024322 is a potent ATP-competitive inhibitor of pan-CDK against cell cycle kinases CDK1, CDK2, and CDK4(Ki values in the 1-3 nM range)
价 格：￥电议型 号：T14136产 地：中国大陆
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T14072A-443654；化合物A-443654A-443654
A-443654 is a pan-Akt inhibitor. A-443654 has equal potency against Akt1, Akt2, or Akt3 within cells (Ki=160 pM).
价 格：￥电议型 号：T14072产 地：中国大陆
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T140434-(tert-Butyl)-benzhydroxamic Acid；化合物 T140434-(tert-Butyl)-benzhydroxamic Acid
4-(tert-Butyl)-benzhydroxamic Acid is a PqsR antagonist with IC50s of 12.5 μM and 23.6 μM for E. coli and P. aeruginosa, respectively, and it reduces the production of the virulence factor pyocyanin in P. aeruginosa with an IC50 of 87.2 μM[1].
价 格：￥电议型 号：T14043产 地：中国大陆
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T140243,4-Dibromo-Mal-PEG2-amine；化合物 T140243,4-Dibromo-Mal-PEG2-amine
3,4-Dibromo-Mal-PEG2-amine is a polyethylene glycol (PEG) derivative and serves as a PEG-based PROTAC linker, facilitating the synthesis of PROTACs[1].
价 格：￥电议型 号：T14024产 地：中国大陆
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T13950UC-514321；化合物UC-514321UC-514321
UC-514321 directly targets STAT3/5 and represses TET1 expression. UC-514321 has the potential to treat acute myeloid leukemia (AML) both in vitro and in vivo, with low toxicity.
价 格：￥电议型 号：T13950产 地：中国大陆
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T13943Tubulysin I；微管蛋白抑制剂 ITubulysin I
Tubulysin I is a natural product isolated from the myxobacterial species Archangium geophyra and Angiococcus disciformis, and is a highly cytotoxic peptide. Tubulysin I is a cytotoxic activity tubulysin which inhibits tubulin polymerization and leads to cell cycle arrest and apoptosis.
价 格：￥电议型 号：T13943产 地：中国大陆
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T13843PROTAC IRAK4 ligand-1；化合物 T13843PROTAC IRAK4 ligand-1
PROTAC IRAK4 ligand-1 is a synthetic ligand for interleukin-1 receptor-associated kinase 4.
价 格：￥电议型 号：T13843产 地：中国大陆
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T13782MS432；化合物 T13782MS432
MS432 is a highly selective PD0325901-based VHL-recruiting PROTAC degrader for MEK1 and MEK2.
价 格：￥电议型 号：T13782产 地：中国大陆
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T13780MS1943；化合物MS1943MS1943
MS1943 is a orally bioavailable EZH2 selective degrader(IC50 of 120 nM).
价 格：￥电议型 号：T13780产 地：中国大陆
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T13743JH-XI-10-02；化合物 T13743JH-XI-10-02
JH-XI-10-02 causes proteasomal degradation, does not affect CDK8 mRNA levels. JH-XI-10-02 shows no effect on CDK19. JH-XI-10-02 is a potent and selective degrader of CDK8, with an IC50 of 159 nM, based on PROTAC.
价 格：￥电议型 号：T13743产 地：中国大陆
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T13643Demethoxydeacetoxypseudolaric acid B analog去甲氧基去乙酰氧基土槿甲酸B类似物脱甲氧基脱乙酰土槿皮乙酸|||去甲氧基去乙酰氧基土槿甲酸B类似物
Demethoxydeacetoxypseudolaric acid B analog has potent activities against HMEC-1, HL-60, A-549, MB-MDA-468, BEL-7402, HCT116, and Hela cells with IC50s ranging from 0.136 to 1.162 μM. and is semi-synthesized by efficient routines from Pseudolaric acid B.
价 格：￥电议型 号：T13643产 地：中国大陆
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T13568LBCX 1470 hydrochloride；BCX 1470 盐酸盐BCX 1470 hydrochloride(217099-43-9 Free base)|||BCX1470 HCl；BCX 1
BCX 1470 hydrochloride is a potent serine protease inhibitor with anti-inflammatory activity that inhibits the ester hydrolysis and haemolytic activity of factor D and C1s, and can be used to study oedema.
价 格：￥电议型 号：T13568L产 地：中国大陆
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T13530AF40431化合物 T13530AF-40431|||AF40431
AF40431 is the first reported small-molecule ligand of sortilin (IC50: 4.4 μM; Kd: 0.7 μM). AF40431 is bound in the neurotensin-binding site of sortilin.
价 格：￥电议型 号：T13530产 地：中国大陆
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T13504360A iodide化合物 T13504360 A iodide
360A iodide is a selective stabilizer of G-quadruplex and inhibits telomerase activity (IC50: 300 nM in TRAP-G4 assay).
价 格：￥电议型 号：T13504产 地：中国大陆
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T134943α-Hydroxymogroside IA1；化合物 T134943α-Hydroxymogroside IA1
3α-Hydroxymogroside IA1 is a mogroside derivative.
价 格：￥电议型 号：T13494产 地：中国大陆
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T13443(R)-Equol；R-雌马酚(+)-Equol；(+)-Equol|||R-雌马酚
(R)-Equol ((+)-Equol) is an ERα and ERβ agonist with Kis of 27.4 and 15.4 nM, respectively.
价 格：￥电议型 号：T13443产 地：中国大陆
