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T15512Hydroxy-PEG1-(CH2)2-Boc;化合物 T15512Hydroxy-PEG1-(CH2)2-Boc
Hydroxy-PEG1-(CH2)2-Boc is a polyethylene glycol (PEG)-based linker used in the synthesis of proteolysis-targeting chimeric molecules (PROTACs)[1].
价 格:¥电议型 号:T15512产 地:中国大陆
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T15511Hydroxy-PEG1-C2-methyl ester;化合物 T15511Methyl 3-(2-hydroxyethoxy)propanoate;Methyl 3-(2-hydroxyethox
Hydroxy-PEG1-C2-methyl ester is a polyethylene glycol (PEG) derived linker widely employed for the production of PROTACs - proteolysis targeting chimeras. [1]
价 格:¥电议型 号:T15511产 地:中国大陆
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T15510Hydroxy-PEG1-acid;化合物 T15510Hydroxy-PEG1-acid
Hydroxy-PEG1-acid is a non-cleavable 1-unit polyethylene glycol (PEG) linker utilized for the synthesis of antibody-drug conjugates (ADCs)[1].
价 格:¥电议型 号:T15510产 地:中国大陆
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T1551Tegaserod maleate;马来酸替加色罗HTF-919|||SDZ-HTF-919;HTF-919|||马来酸替加色罗|||SDZ-HTF-919
Tegaserod maleate (SDZ-HTF-919) is a 5-HT4 agonist manufactured by Novartis and used for the management of irritable bowel syndrome and constipation. Its use was the only drug approved by the United States Food and Drug Administration to help relieve the abdominal discomfort, bloating and constipation associated with irritable bowel syndrome. On March 30, 2007, the U.S. Food and Drug Administration requested that Novartis withdraw Zelnorm from shelves. The FDA alleges a relationship between pres
价 格:¥电议型 号:T1551产 地:中国大陆
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T15451GW-870086;化合物GW-870086GW-870086
GW-870086 is an effective anti-inflammatory agent. GW-870086 also plays a role in a glucocorticoid receptor agonist (pIC50: 10.1 in A549 cells expressing NF-κB).
价 格:¥电议型 号:T15451产 地:中国大陆
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T1542Pirenzepine dihydrochloride;盐酸哌仑西平Pirenzepine HCl|||Bisvanil|||Tabe|||LS519;Pirenzepine HCl|||Bisvan
Pirenzepine dihydrochloride (LS519) is a selective M1 muscarinic receptor antagonist, inhibiting gastric secretion.
价 格:¥电议型 号:T1542产 地:中国大陆
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T15410GNF351;化合物GNF351GNF351
GNF351 is a full antagonist of the aryl hydrocarbon receptor (AHR)with the capacity to inhibit both DRE-dependent and -independent activity. GNF351 is minimal toxicity in mouse or human keratinocytes. GNF351 competes with a photoaffinity AHR ligand for binding to the AHR (IC50: 62 nM).
价 格:¥电议型 号:T15410产 地:中国大陆
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T15366Gabapentin enacarbil加巴喷丁酯XP-13512|||加巴喷丁酯
Gabapentin enacarbil (XP-13512) is a prodrug for the anticonvulsant and analgesic drug gabapentin. Gabapentin enacarbil provides sustained dose-proportional exposure to gabapentin and predictable bioavailability.
价 格:¥电议型 号:T15366产 地:中国大陆
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T15351FT827;化合物 FT827FT827
FT827 is a covalent inhibitor of selective ubiquitin-specific protease 7 (USP7) (Ki=4.2 ?M, Kd=7.8 ?M) targeting the catalytic center of the autoinhibitory apolipoprotein form of USP7 for cancer research.
价 格:¥电议型 号:T15351产 地:中国大陆
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T1528Azasetron hydrochloride盐酸阿扎司琼Y-25130 hydrochloride|||Y-25130 HCl|||盐酸阿扎司琼|||Azasetron HCl
Azasetron hydrochloride (Y-25130 HCl) is a 5-HT3 receptor antagonist which is used as an anti-emetic.
价 格:¥电议型 号:T1528产 地:中国大陆
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T15251Etebenecid;乙磺舒Urelim;乙磺舒|||Urelim
Etebenecid (Urelim) is uricosuric agents, which lower uric acid levels in the body by increasing the elimination of uric acid by the kidneys. It also inhibits penicillin tubular secretion.
价 格:¥电议型 号:T15251产 地:中国大陆
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T15219Enarodustat;化合物EnarodustatHIF/HIF Prolyl-Hydroxylase|||HIFs|||inhibit|||JTZ951|||HIF-PH|||Hypoxia-in
Enarodustat (JTZ-951) is an orally active factor inhibitor of prolyl hydroxylase (EC50: 0.22 μM) and has the potential for renal anemia treatment.
价 格:¥电议型 号:T15219产 地:中国大陆
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T1519LRimonabant;利莫那班SR141716;SR141716|||利莫那班
Rimonabant (SR141716) is an inverse agonist for the cannabinoid receptor CB1. It is an anorectic anti-obesity drug produced and marketed by Sanofi-Aventis. Its main avenue of effect is a reduction in appetite. Rimonabant is the first selective CB1 receptor blocker to be approved for use anywhere in the world. Rimonabant is approved in 38 countries including the E.U., Mexico, and Brazil. It was rejected for approval for use in the United States.
价 格:¥电议型 号:T1519L产 地:中国大陆
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T15199Edicotinib;化合物EdicotinibJNJ-527|||JNJ-40346527;JNJ-527|||JNJ-40346527
Edicotinib (JNJ-527) is a brain penetrant and orally active inhibitor of the colony-stimulating factor-1 receptor (IC50: 3.2 nM). It shows less inhibitory effects on KIT and FLT3 (IC50: 20 nM and 190 nM). It has the potential for Alzheimer´s disease and rheumatoid arthritis treatment.
价 格:¥电议型 号:T15199产 地:中国大陆
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T15198Edasalonexent;依达柰珍CAT-1004;CAT-1004
Edasalonexent (CAT-1004) is an orally available NF-κB inhibitor for the improvement of Duchenne muscular dystrophy.
价 格:¥电议型 号:T15198产 地:中国大陆
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T15197Echinomycin;化合物 T15197Quinomycin A|||NSC-13502;Quinomycin A|||NSC-13502
Echinomycin is a cell-permeable hypoxia-inducible factor-1 (HIF-1) DNA-binding activity inhibitor. Echinomycin selectively inhibits the cancer stem cells (CSCs; IC50: 29.4 pM).
价 格:¥电议型 号:T15197产 地:中国大陆
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T15196EC23;化合物EC23BASF-46928|||AGN 190205;BASF-46928|||AGN 190205
EC23 (AGN 190205) is a stable synthetic retinoid analogue. It is also induces neuronal differentiation.
价 格:¥电议型 号:T15196产 地:中国大陆
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T15195Ebrotidine;乙溴替丁FI3542;FI3542|||乙溴替丁
Ebrotidine (FI3542) is a competitive H2-receptor antagonist with Ki of 127.5 nM. Ebrotidine has a potent antisecretory activity and evidenced gastroprotection.
价 格:¥电议型 号:T15195产 地:中国大陆
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T15194EBI-2511;化合物EBI-2511EBI-2511
EBI-2511 is a highly potent and orally active inhibitor of EZH2 (IC50: 6 nM in Pfeffiera cell lines).
价 格:¥电议型 号:T15194产 地:中国大陆
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T15193EBI-1051;化合物 T15193EBI-1051
EBI-1051 is a highly potent and orally efficacious inhibitor of MEK (IC50: 3.9 nM).
价 格:¥电议型 号:T15193产 地:中国大陆