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T11309FMF-04-159-2;化合物 T11309FMF-04-159-2
FMF-04-159-2 inhibits CDK14 and CDK2 with IC50s of 39.6 nM and 256 nM in NanoBRET assay, respectively. FMF-04-159-2 is a covalent CDK14 inhibitor.
价 格:¥电议型 号:T11309产 地:中国大陆
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T11286Fiduxosin;非多唑嗪A 185980.1|||ABT 980;A 185980.1|||ABT 980
Fiduxosin is a selective and potent α1-adrenoceptor antagonist with inhibitory effects on α1a-adrenoceptor, α1b-adrenoceptor and α1d-adrenoceptor, with Ki values of 0.160 nM, 24.9 nM and 0.920 nM, respectively. Fiduxosin can be used for the treatment of benign prostatic hyperplasia.
价 格:¥电议型 号:T11286产 地:中国大陆
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T11259FadD32 Inhibitor-1;化合物 T11259FadD32 Inhibitor-1
FadD32 inhibitor -1 has anti-tuberculosis activity and is an effective FadD32 inhibitor.
价 格:¥电议型 号:T11259产 地:中国大陆
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T111959IFB-088 acetate;IFB-088 醋酸盐IFB-088 acetate
IFB-088 acetate, a benzyl guanidine derivative, is used to treat diseases and cancers associated with the PPP1R15A pathway and associated with protein misfolding stress, Examples include tau disease, synaptic riboprotein disease, polyglutamine and polyalanine diseases, leukodystrophy, cystic fibrosis, multiple sclerosis, lysosome storage disorders, amyloidosis diseases, inflammation, metabolic disorders, cardiovascular diseases, osteoporosis, neurological trauma, and more.
价 格:¥电议型 号:T111959产 地:中国大陆
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T11172EIPA hydrochloride;化合物 T11172L593754 hydrochloride|||MH 12-43 hydrochloride;L593754 hydrochloride|||
EIPA hydrochloride also inhibits Na+/H+-exchanger (NHE) and macropinocytosisEIPA hydrochloride (L593754 hydrochloride) is a TRPP3 channel inhibitor with an IC50 of 10.5 μM.
价 格:¥电议型 号:T11172产 地:中国大陆
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T11159EGFR-IN-2;化合物 T11159EGFR-IN-2
EGFR-IN-2 is a non-covalent, mutation-selective and irreversible second-generation EGFR inhibitor.
价 格:¥电议型 号:T11159产 地:中国大陆
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T11146EC359;化合物EC359EC-359;EC-359
EC359 is a potent and selective inhibitor of leukemia inhibitory factor receptor (LIFR), a potent inhibitor with anticancer activity, blocks LIF/LIFR interaction, and can be used in the study of leukemia and endometrial cancer.
价 格:¥电议型 号:T11146产 地:中国大陆
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T11059DM4-SMe;化合物 T11059DM4-SMe
DM4-SMe is a cytotoxic part of antibody-drug conjugates (ADCs) and a metabolite of antibody-maytansin conjugates (AMCs) and tubulin inhibitors, which can also be stabilized by disulfide bonds or thioether The bond binds to the antibody. The IC50 of DM4-SMe on KB cells was 0.026 nM.
价 格:¥电议型 号:T11059产 地:中国大陆
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T11033DI-591;化合物 T11033DI-591
DI-591 is an effective, high-affinity and cell-permeability inhibitor for DCN1-UBC12 interaction. DI-591 binds to DCN1 and DCN2 with Ki values of 12 and nM and 10.4 nM, respectively, and has no obvious binding to DCN3, DCN4 and DCN5 proteins.
价 格:¥电议型 号:T11033产 地:中国大陆
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T10959Daphnin;祖师麻乙素Daphnin
Daphnin is one of the main coumarin bioactive ingredients with antibacterial activity. Daphnine is isolated from the entire Daphne fragrance, which is a folk medicine used in China to relieve fever.
价 格:¥电议型 号:T10959产 地:中国大陆
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T10859COH34;化合物COH341-[(E)-(4-methylphenyl)sulfanyliminomethyl]naphthalen-2-ol;1-[(E)-(4-methylphenyl)sulf
COH34 (1-[(E)-(4-methylphenyl)sulfanyliminomethyl]naphthalen-2-ol) is a selective inhibitor of PARG with an IC50 of 0.37 nM and a Kd of 0.547 μM. COH34 prolongs PARylation at DNA lesions and traps DNA repair factors.
价 格:¥电议型 号:T10859产 地:中国大陆
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T10759CEP-28122 mesylate salt (1022958-60-6 free base);化合物CEP-28122 mesylate saltCEP-28122 mesylate salt;C
CEP-28122 mesylate salt (1022958-60-6 free base) is a highly selective orally active ALK inhibitor (IC50: 1.9 nM in an enzyme-based TRF assay).
价 格:¥电议型 号:T10759产 地:中国大陆
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T10691CAY10595;化合物CAY10595CAY10595
CAY10595 is an antagonist of the CRTh2 (DP2) receptor with a Ki of 10 nM.
价 格:¥电议型 号:T10691产 地:中国大陆
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T10659Ca2+ channel agonist 1;化合物Ca2+ channel agonist 1Ca2+ channel agonist 1
Ca2+ channel agonist 1 is an agonist of N-type Ca2+ channel and an inhibitor of Cdk2 (EC50s: 14.23 μM and 3.34 μM) and is used as a potential treatment for motor nerve terminal dysfunction.
价 格:¥电议型 号:T10659产 地:中国大陆
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T10605BRD-K98645985;化合物 T10605BRD-K98645985
BRD-K98645985 is a BAF transcriptional repression inhibitor (EC50: ~2.37 μM). It binds ARID1A-specific BAF complexes, potently reverses HIV-1 latency and prevents nucleosomal positioning.
价 格:¥电议型 号:T10605产 地:中国大陆
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T10599BRAF inhibitor;化合物BRAF inhibitorBRAF inhibitor
BRAF inhibitor is an inhibitor of B-Raf.
价 格:¥电议型 号:T10599产 地:中国大陆
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T10598BR351 precursor;化合物 T10598BR351 precursor
BR351 precursor is a precursor of BR351. BR351 is a brain penetrant MMP inhibitor (IC50s: 4, 2, 11, 50 nM for MMP2, MMP8, MMP9 and MMP13).
价 格:¥电议型 号:T10598产 地:中国大陆
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T10597BR351;化合物 T10597BR351
BR351 is a brain penetrant MMP inhibitor (IC50s: 4, 2, 11, 50 nM for MMP2, MMP8, MMP9 and MMP13).
价 格:¥电议型 号:T10597产 地:中国大陆
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T10596BR102375;化合物 T10596BR102375
BR102375 is a non-TZD PPAR γ full agonist (EC50: 0.28 μM) for the treatment of type 2 diabetes.
价 格:¥电议型 号:T10596产 地:中国大陆
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T10595LBQ-788 sodium salt;化合物 T10595LBQ-788 sodium salt
BQ-788 sodium salt is a potent and selective antagonist of ETB receptor(ETB receptors with an IC50 of 1.2 nM in human Girrardi heart cells).
价 格:¥电议型 号:T10595L产 地:中国大陆