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T8706STAMBP-IN-1;化合物 STAMBP-IN-1STAMBP-IN-1
STAMBP-IN-1 is a novel selective antagonist of deubiquitinase STAM-binding protein (STAMBP), decreasing NALP7 protein levels and suppressing IL-1β release after TLR agonism.
价 格:¥电议型 号:T8706产 地:中国大陆
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T8703yGsy2p-IN-1;化合物yGsy2p-IN-1yGsy2p-IN-1
yGsy2p-IN-1 is a potent yeast glycogen synthase 2 (yGsy2p) and human glycogen synthase 1 (hGYS1) inhibitor. yGsy2p-IN-H23 a pyrazole inhibitor,and is used for glycogen storage diseases (GSDs)
价 格:¥电议型 号:T8703产 地:中国大陆
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T8659K-Ras-PDEδ-IN-1;化合物K-Ras-PDEδ-IN-1K-Ras-PDEδ-IN-1
K-Ras-PDEδ-IN-1 is a potent inhibitor of competitive K-Ras-PDEδ.It binds to the farnesyl binding pocket of PDEδ(Kd of 8 nM).
价 格:¥电议型 号:T8659产 地:中国大陆
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T8587EcDsbB-IN-12;化合物EcDsbB-IN-124,5-dichloro-2-[(2-chlorophenyl)methyl]pyridazin-3-one;4,5-dichloro-2-[(
EcDsbB-IN-12 (4,5-dichloro-2-[(2-chlorophenyl)methyl]pyridazin-3-one) targets disulfide bond forming enzyme,and is a novel potent specific inhibitor of EcDsbB.
价 格:¥电议型 号:T8587产 地:中国大陆
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T8579Nav1.8-IN-1;化合物T85795-(4-Chlorophenyl)-N-[[2-(2,2,2-trifluoroethoxy)pyridin-3-yl]methyl]pyridine-3-c
Nav1.8-IN-1 (CHEMBL1270208) is an inhibitor of human NaV1.8
价 格:¥电议型 号:T8579产 地:中国大陆
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T8555Neuraminidase-IN-1;化合物Compound Y-1Novel NA Inhibitor|||Compound Y-1;Novel NA Inhibitor|||Compound Y-
Neuraminidase-IN-1 (Compound Y-1) is a novel neuraminidase inhibitor.
价 格:¥电议型 号:T8555产 地:中国大陆
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T8525EGFR-IN-16;化合物AG473AG473;AG473
EGFR-IN-16 (AG473) is an inhibitor of EGFR in human A431 cells.
价 格:¥电议型 号:T8525产 地:中国大陆
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T8467RET V804M-IN-1;化合物RET V804M-IN-1RETV804M kinase inhibitor|||LUN09945;RETV804M kinase inhibitor|||LUN
RET V804M-IN-1 (RETV804M kinase inhibitor) is a wt-RET -selective RETV804M kinase inhibitors(IC50 = 20 nM).
价 格:¥电议型 号:T8467产 地:中国大陆
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T8418DCLK1-IN-1;化合物DCLK1-IN-1DCLK1-IN-1
DCLK1-IN-1 is a selective and in vivo-compatible chemical probe of the DCLK1 kinase domain .
价 格:¥电议型 号:T8418产 地:中国大陆
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T8409SYN1143;化合物AMG-1RON-IN-1|||AMG-1;RON-IN-1|||AMG-1
SYN1143 (AMG-1) is a potent inhibitor of human RON and c-Met.In vitro kinase assays showed that compound I is a potent inhibitor of human RON and c-Met with IC50s of 9 and 4 nmol/L, respectively.
价 格:¥电议型 号:T8409产 地:中国大陆
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T83658SQLE-IN-1;SQLE 抑制剂1SQLE-IN-1
SQLE-IN-1 is a squalene epoxidase (SQLE) inhibitor with anti-tumor activity. It can inhibit the proliferation and migration of liver cancer cell line Huh7, inhibit the production of cellular cholesterol, and increase the expression of the tumor suppressor gene PTEN. expression, inhibiting the protein expression of PI3K and AKT.
价 格:¥电议型 号:T83658产 地:中国大陆
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T83628TNF/IFNγ-IN-1;TNF/IFNγ抑制剂1TNF/IFNγIN1;0
TNF/IFNγ-IN-1 (TGA) is a dual inhibitor of TNF and IFN-γ. TNF/IFNγ-IN-1 has potential antioxidant and anti-inflammatory activities for neurodegenerative diseases such as Alzheimer.
价 格:¥电议型 号:T83628产 地:中国大陆
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T83625iNOS-IN-14;化合物 iNOS-IN-143-bromo-1H-indazole-7-carbonitrile;3-bromo-1H-indazole-7-carbonitrile
iNOS-IN-14 (3-bromo-1H-indazole-7-carbonitrile) is a potent nitric oxide synthase (NOS) inhibitor that inhibits the NADPH oxidase activity of nNOS.
价 格:¥电议型 号:T83625产 地:中国大陆
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T8345712R-LOX-IN-1;化合物 12R-LOX-IN-112R-LOX-IN-1
12R-LOX-IN-1 (Compound 4a), with an IC50 of 28.25 ?M, is an inhibitor of 12R-LOX. It suppresses the hyperproliferative condition and the ability to form colonies in Imiquimod-induced psoriatic keratinocytes, as well as reducing levels of reactive oxygen species, Ki67, IL-17A, TNF-α, and IL-6. This compound has utility in antipsoriatic research [1].
价 格:¥电议型 号:T83457产 地:中国大陆
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T8323LolCDE-IN-1;化合物LolCDE-IN-1LolCDE-IN-1
LolCDE-IN-1 is an inhibitor of the Lol proteins (LolCDE) complex. LolCDE-IN-1 shows antibacterial activity.
价 格:¥电议型 号:T8323产 地:中国大陆
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T83169Adenylyl cyclase-IN-1;化合物 Adenylyl cyclase-IN-1Adenylyl cyclase-IN-1
Adenylyl cyclase-IN-1 is a potential adenylyl cyclase inhibitor for ocular hypotonia research [1].
价 格:¥电议型 号:T83169产 地:中国大陆
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T83137ALP/Carbonic anhydrase-IN-1;化合物 ALP/Carbonic anhydrase-IN-1ALP/Carbonic anhydrase-IN-1
Compound 1e, also known as ALP/Carbonic anhydrase-IN-1, is a dual inhibitor targeting both carbonic anhydrase (CA) isozymes II, IX, and XII, as well as alkaline phosphatase (ALP). It exhibits inhibitory IC50 values of 0.44 ?M for CA-II, 1.61 ?M for CA-IX, 0.51 ?M for CA-XII, and 0.107 ?M for ALP [1].
价 格:¥电议型 号:T83137产 地:中国大陆
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T83120And1-IN-1;化合物 And1-IN-1And1-IN-1
And1-IN-1, also known as compound III, is a potent inhibitor of And1 [1].
价 格:¥电议型 号:T83120产 地:中国大陆
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T8310MMP-9-IN-1;化合物MMP-9-IN-1MMP-9-IN-1
MMP-9-IN-1 is an inhibitor of specific matrix metalloproteinase-9 (MMP-9).
价 格:¥电议型 号:T8310产 地:中国大陆
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T82965ARTD3/PARP3-IN-1;化合物 ARTD3/PARP3-IN-1ARTD3/PARP3-IN-1
ARTD3/PARP3-IN-1 is a non-selective inhibitor targeting diphtheria toxin-like ADP-ribosyltransferase 3 (ARTD3)/PARP3 [1].
价 格:¥电议型 号:T82965产 地:中国大陆