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T80083Zilucoplan TFA;化合物 Zilucoplan TFARA101495 TFA;RA101495 TFA
Zilucoplan TFA (RA101495), a 15-amino acid macrocyclic peptide, serves as a potent inhibitor of complement component 5 (C5). It has applications in the study of immune-mediated necrotising myopathy (IMNM) [1] [2].
价 格:¥电议型 号:T80083产 地:中国大陆
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T79249Antitumor agent-101;化合物 Antitumor agent-101Antitumor agent-101
Antitumor agent-101 is a selective, covalent inhibitor targeting lysine methyltransferases G9a/GLP, demonstrating IC50 values of 8.5 nM for G9a and 5.5 nM for GLP. It exhibits antitumor efficacy in the PANC-1 xenograft model [1].
价 格:¥电议型 号:T79249产 地:中国大陆
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T79101β-Catenin modulator-2;化合物 β-Catenin modulator-2β-Catenin modulator-2
β-Catenin Modulator-2 (Compound IIa-130), which is an oxazole-thiazole derivative, serves as a potent and selective modulator of β-Catenin [1].
价 格:¥电议型 号:T79101产 地:中国大陆
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T78990Biotin-labeled ODN 1018 sodium;化合物 Biotin-labeled ODN 1018 sodiumBiotin-labeled ODN 1018 sodium
Biotin-labeled ODN 1018 (sodium), a TLR-9 agonist oligodeoxynucleotide, serves as a tool for assessing cellular uptake and localization of CpG ODNs through biotin detection systems and light microscopy.
价 格:¥电议型 号:T78990产 地:中国大陆
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T78871PLM-101;化合物 PLM-101PLM-101
PLM-101 is an anticancer compound orally active against acute myeloid leukemia by targeting FLT3 and RET. It impedes RET function, promoting autophagic breakdown of FLT3, and suppresses the PI3K and Ras/ERK pathways, contributing to its anti-leukemic effects. The compound´s antitumor efficacy is demonstrated in both a mouse MV4-11 flank xenograft model (doses of 3 and 10 mg/kg; po) and an allogeneic xenograft mouse model (dose of 40 mg/kg; po) [1].
价 格:¥电议型 号:T78871产 地:中国大陆
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T7878Halosulfuron-methyl;氯吡嘧磺隆A841101|||Sempra|||A 841101|||A-841101;A841101|||Sempra|||A 841101|||氯吡嘧磺隆|
Halosulfuron-methyl (A841101) is a common herbicide.
价 格:¥电议型 号:T7878产 地:中国大陆
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T78657Azilsartan mepixetil potassium;化合物 Azilsartan mepixetil potassiumQR-01019K;QR-01019K
Azilsartan medoxomil potassium (QR-01019K), an angiotensin II receptor antagonist, exhibits a potent and sustained antihypertensive effect, along with a more pronounced and enduring reduction in heart rate, and a high safety profile. It shows promise for investigation in the management of hypertension, chronic heart failure, and diabetic nephropathy[1].
价 格:¥电议型 号:T78657产 地:中国大陆
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T78101Zymosan A酵母聚糖AZymosan A from Saccharomyces cerevisiae
Zymosan A, derived from Saccharomyces cerevisiae, is a TLR2 agonist and exhibits significant radioprotective effects, mitigating and preventing IR-induced intestinal injury in mice. Furthermore, Zymosan A aids in the regeneration of intestinal stem cells (ISCs) following IR injury [1].
价 格:¥电议型 号:T78101产 地:中国大陆
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T78089FITC-labeled ODN 1018 sodium;化合物 FITC-labeled ODN 1018 sodiumFITC-labeled ODN 1018 sodium
FITC-labeled ODN 1018 (sodium), a TLR-9 agonist oligodeoxynucleotide, facilitates the assessment of CpG ODN cellular uptake and localization through confocal laser-scanning microscopy (excitation 495 nm, emission 520 nm) or flow cytometry.
价 格:¥电议型 号:T78089产 地:中国大陆
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T78054JNJ-1013;化合物 JNJ-1013JNJ-1013
JNJ-1013 is a potent and selective IRAK1 degrader, demonstrating IC50 values of 72 nM for IRAK1, 443 nM for IRAK4, and 1071 nM for VHL FP. It induces apoptosis and augments the expression of cleaved PARP while decreasing the expression of IRAK1, p-IKBα, and pSTAT3(Tyr705) [1].
价 格:¥电议型 号:T78054产 地:中国大陆
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T77407Ensituximab;恩妥昔单抗NPC-1C|||NEO-102|||NEO-101;NPC-1C|||NEO-102|||NEO-101
Ensituximab (NEO-102) is a quasi-selective IgG1 monoclonal antibody against the MUC5AC variant with anti-tumour activity that inhibits colorectal and pancreatic cancer.
价 格:¥电议型 号:T77407产 地:中国大陆
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T77399Crizanlizumab克立利珠单抗ADAKVEO|||SEG-101
Crizanlizumab (Adakveo) is a humanized monoclonal antibody against P-selectin for the prevention of pain crises in sickle cell disease.
价 格:¥电议型 号:T77399产 地:中国大陆
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T77101Nivatrotamab;化合物 NivatrotamabNivatrotamab
Nivatrotamab (Hu3F8-BsAb), a humanized anti-GD2/CD3 bispecific antibody and T-cell engager specific to CD3 and GD2, is employed in the study of neuroblastoma [1].
价 格:¥电议型 号:T77101产 地:中国大陆
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T76101Ascorbate oxidase;化合物 Ascorbate oxidaseAscorbate oxidase
Ascorbate oxidase, or Vitamin C oxidase, is a redox (REDOX) enzyme that plays a crucial role in extracellular matrix regulation by catalyzing the oxidation of ascorbic acid to dehydroascorbic acid in the presence of oxygen [1] [2].
价 格:¥电议型 号:T76101产 地:中国大陆
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T75895UFP-101 TFA;化合物 UFP-101 TFAUFP-101 TFA
UFP-101 TFA is a potent, selective, and competitive N/OFQ peptide (NOP) receptor antagonist, boasting a pK i value of 10.24 and demonstrating over 3000-fold selectivity against δ, μ, and κ opioid receptors. It exhibits antidepressant-like effects [1] [2].
价 格:¥电议型 号:T75895产 地:中国大陆
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T75720Thrombospondin-1 (1016-1023) (human, bovine, mouse);Thrombospondin-1 (1016-1023) (人, 牛, 鼠)Thrombospo
Thrombospondin-1 (1016-1023) (human, bovine, mouse) is part of Thrombospondin-1 (TSP-1), a peptide with CD47 agonism.
价 格:¥电议型 号:T75720产 地:中国大陆
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T7512BMS-191011;化合物BMS-191011BMS-A;BMS-A
BMS-191011 (BMS-A) is an activator of large-conductance calcium-activated potassium (BKCa) channels ,effective in stroke models
价 格:¥电议型 号:T7512产 地:中国大陆
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T75101BAY-728;化合物 BAY-728BAY-728
BAY-728 serves as a negative control for BAY-805, a potent and selective inhibitor of USP21 [1].
价 格:¥电议型 号:T75101产 地:中国大陆
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T74902ODN 1018;化合物 ODN 1018ODN 1018
ODN 1018 (1018 ISS), an oligodeoxynucleotide and a TLR-9 agonist, serves as a synthetic immunostimulatory sequence and vaccine adjuvant. The sequence is 5′-TGACTGTGAACGTTCGAGATGA-3′ [1] [2].
价 格:¥电议型 号:T74902产 地:中国大陆
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T74874CpG ODN 10101;化合物 CpG ODN 10101ODN 10101;ODN 10101
CpG ODN 10101 (CPG 10101) is a novel potent and selective Toll-like receptor 9 (TLR9)-containing oligodeoxynucleotide agonist with antiviral activity for the treatment of chronic infections.
价 格:¥电议型 号:T74874产 地:中国大陆