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T17667Boc-NH-PEG12-CH2CH2COOH叔丁氧羰基十二聚乙二醇羧乙基叔丁氧羰基十二聚乙二醇羧乙基
Boc-NH-PEG12-CH2CH2COOH is a PEG-based PROTAC linker that can be used in PROTAC synthesis.
价 格:¥电议型 号:T17667产 地:中国大陆
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T16759Ritanserin;利坦丝林R 55667;利坦丝林|||R 55667
Ritanserin (R 55667) is a highly effective, relatively selective, long-acting antagonist of 5-HT2 receptor (IC50: 0.9 nM), less active on Histamine H1, Dopamine D2, Adrenergic α1, Adrenergic α2 receptors.
价 格:¥电议型 号:T16759产 地:中国大陆
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T16679Belzutifan;化合物BelzutifanPT2977|||MK-6482;PT2977|||MK-6482
Belzutifan (MK-6482) is a potential treatment for clear cell renal cell carcinoma (ccRCC). Belzutifan is an orally active and selective HIF-2α inhibitor (IC50: 9 nM). Belzutifan , as a second-generation HIF-2α inhibitor, increases potency and improves pharmacokinetic profile.
价 格:¥电议型 号:T16679产 地:中国大陆
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T16678PSN632408;化合物 T16678PSN632408
PSN632408 is an optimized agonist of GPR119 receptors that display similar potency to OEA at both recombinant mouse and human GPR119 receptors (EC50: 5.6 and 7.9 uM, respectively).
价 格:¥电议型 号:T16678产 地:中国大陆
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T16677Psicofuranine;化合物 T16677Psicofuranine
Psicofuranine also specifically inhibits GMP synthase and interrupts parasite growth. Psicofuramine is a nucleoside antibiotic. It has the inhibition of xanthosine 5´-phosphate aminase. Psicofuranine shows dose-dependent inhibition of P. falciparum growth(IC50: 0.3 mM).
价 格:¥电议型 号:T16677产 地:中国大陆
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T16676PSI-697;化合物 T16676P-Selectin Inhibitor;P-Selectin Inhibitor
PSI-697 is an inhibitor of oral P-selectin (IC50: 125 μM).
价 格:¥电议型 号:T16676产 地:中国大陆
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T16674Pseudouridine;假尿苷Pseudouridine
Pseudouridine is the most abundant modified nucleoside in non-coding RNAs. It enhances the function of transfer RNA and ribosomal RNA by stabilizing RNA structure.
价 格:¥电议型 号:T16674产 地:中国大陆
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T16673Pseudouridimycin;化合物 T16673PUM;PUM
Pseudouridimycin is a C-nucleoside analogue. Pseudouridimycin is an antibiotic and is a selective bacterial RNA polymerase (RNAP) inhibitor. It is effective against both Gram-negative and Gram-positive bacteria.
价 格:¥电议型 号:T16673产 地:中国大陆
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T16672PSB-1114 tetrasodium;化合物 T16672PSB-1114 tetrasodium
PSB-1114 tetrasodium shows >50-fold selectivity versus the P2Y4 (EC50: 9.3 μM) and P2Y6 (EC50: 7.0 μM) receptors. PSB-1114 tetrasodium is an effective, enzymatically stable, and subtype-selective P2Y2 receptor agonist (EC50: 134 nM) .
价 格:¥电议型 号:T16672产 地:中国大陆
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T16671PS315;化合物 T16671PS315
PS315 inhibits the full-length and catalytic domain constructs of PKCζ (IC50=10 μM) and PKCη (IC50=30 μM). PS315 has anti-cancer activity. PS315 is a derivative of PS48 and is an allosteric PKC inhibitor by binding to the PIF-pocket of aPKC and inducing displacement of the active site residue Lys111.
价 格:¥电议型 号:T16671产 地:中国大陆
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T16670PS210;化合物PS210PS210
PS210 is a potent and selective activator of PDK1 (Kd: 3 μM), specifically targeting the PIF-binding pocket of PDK1, without acting against other protein kinases such as S6K, PKB/Akt, or GSK3. Its prodrug, PS423, serves as a substrate-selective inhibitor of PDK1 in cells, inhibiting the phosphorylation and activation of S6K.
价 格:¥电议型 号:T16670产 地:中国大陆
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T1667Tandutinib;坦度替尼MLN518|||CT53518|||NSC726292;MLN518|||CT53518|||NSC726292|||坦度替尼
Tandutinib (CT53518) (MLN518, CT53518), an effective FLT3 antagonist (IC50: 0.22 μM), can also inhibit c-Kit and PDGFR, 15-20 fold higher potency for FLT3 versus CSF-1R and >100-fold selectivity for the same target versus FGFR, EGFR, and KDR.
价 格:¥电议型 号:T1667产 地:中国大陆
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T16667PROTAC Sirt2 Degrader-1;化合物 T16667PROTAC Sirt2 Degrader-1
PROTAC Sirt2 Degrader-1 is a SirReal-based PROTAC, acts as a Sirt2 degrader, composed of a highly potent and isotype-selective Sirt2 inhibitor, a linker, and a bona fide cereblon ligand for E3 ubiquitin ligase. PROTAC Sirt2 Degrader-1 shows an IC50 of 0.25 μM for Sirt2, with no effect on Sirt1/Sirt3 (IC50s > 100 μM)[1].
价 格:¥电议型 号:T16667产 地:中国大陆
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T16430Paliroden;化合物PalirodenSR 57667|||SR 57667B;SR 57667|||SR 57667B
Paliroden is a non-peptide compound that can be taken orally and is used for supplementing neuro-nutrition. It stimulates the synthesis of endogenous neurotrophic factors and is employed in the research of neurodegenerative diseases such as Alzheimer´s and Parkinson´s.
价 格:¥电议型 号:T16430产 地:中国大陆
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T15667KRN4884;化合物 T15667KRN4884
KRN 4884 is an opener of the K+ channel. KRN 4884 (0.1-3 μM) activates KATP channels in a concentration-dependent manner (EC50=0.55 μM), in the presence of intracellular ATP (1 mM).
价 格:¥电议型 号:T15667产 地:中国大陆
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T14667BLT-1;化合物BLT-1BLT-1
BLT-1 is a scavenger receptor BI (SR-BI)inhibitor.
价 格:¥电议型 号:T14667产 地:中国大陆
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T13667L1Dusquetide aceate;化合物Dusquetide aceateDusquetide aceate (931395-42-5 Free base);Dusquetide aceate (9
Dusquetide aceate is an innate immune defense regulator against damage-associated molecular patterns and pathogen-associated molecular patterns. Dusquetide aceate shows anti-inflammation and antibacterial activities.
价 格:¥电议型 号:T13667L1产 地:中国大陆
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T13667LDusquetide;化合物 T13667LSGX942;SGX942
Dusquetide is a first-in-class innate defense regulator. Dusquetide displays activity in both reducing inflammation and increasing the clearance of bacterial infection.
价 格:¥电议型 号:T13667L产 地:中国大陆
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T13667Dusquetide TFA (931395-42-5 free base);化合物 T13667SGX942 TFA|||Dusquetide TFA;SGX942 TFA|||Dusquetide
Dusquetide TFA is a kind of innate defense regulator (IDR).Dusquetide TFA has been shown to be active in reducing inflammation and increasing clearance of bacterial infections.Dusquetide TFA regulates innate immune responses to PAMPs and DAMPs in combination with P62.
价 格:¥电议型 号:T13667产 地:中国大陆
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T13398ZINC13466751;化合物ZINC13466751ZINC13466751
ZINC13466751 is a potent HIF-1α/von Hippel-Lindau interaction inhibitor(IC50 = 2.0 ?M).
价 格:¥电议型 号:T13398产 地:中国大陆