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T78543Acetyl Gastric Inhibitory Peptide (human) TFA；化合物 Acetyl Gastric Inhibitory Peptide (human) TFAHuman
Acetyl Gastric Inhibitory Peptide (human) TFA, a fatty acid-derivatized analog of the glucose-dependent insulinotropic polypeptide, exhibits enhanced antihyperglycemic and insulinotropic properties. It is utilized in the research of diabetes, insulin resistance, and obesity [1] [2] [3].
价 格：￥电议型 号：T78543产 地：中国大陆
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T78046RG7800 tetrahydrochloride；化合物 RG7800 tetrahydrochlorideRO6885247 tetrahydrochloride；RO6885247 tetrah
RG7800 hydrochloride is an orally active modulator of SMN2 splicing, exhibiting EC50 values of 23 nM for SMN2 splicing and 87 nM for SMN protein production. This compound holds promise as a therapeutic agent for spinal muscular atrophy.
价 格：￥电议型 号：T78046产 地：中国大陆
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T78037Hepcidin-1 (mouse) TFA；化合物 Hepcidin-1 (mouse) TFAHepcidin-1 (mouse) TFA
Hepcidin-1 (mouse) TFA, an endogenous peptide hormone, regulates iron homeostasis by upregulating mRNA levels of TRAP, cathepsin K, and MMP-9, enhancing TRAP-5b protein secretion, and downregulating FPN1 protein levels, thereby increasing intracellular iron. It also promotes osteoclast differentiation [1].
价 格：￥电议型 号：T78037产 地：中国大陆
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T77916(S,R,S)-AHPC-Boc；化合物 (S,R,S)-AHPC-BocVH032-Boc；VH032-Boc
(S,R,S)-AHPC-Boc (VH032-Boc) serves as a ligand for the von Hippel-Lindau (VHL) protein recruitment in PROTAC technology [1].
价 格：￥电议型 号：T77916产 地：中国大陆
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T77732HFY-4A；化合物 HFY-4AHFY-4A
HFY-4A is a novel HDAC inhibitor.HFY-4A has antitumour activity and has shown antiproliferative activity in breast cancer cells.
价 格：￥电议型 号：T77732产 地：中国大陆
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T7752(S,R,S)-AHPC-Me；化合物(S,R,S)-AHPC-MeVHL ligand 2|||E3 ligase Ligand 1A；VHL ligand 2|||E3 ligase Ligand
(S,R,S)-AHPC-Me (E3 ligase Ligand 1A) (VHL ligand 2) is the (S,R,S)-AHPC-based VHL ligand used in the recruitment of the von Hippel-Lindau (VHL) protein[1]. (S,R,S)-AHPC-Me can be used to synthesize ARV-771. ARV-771 is a von Hippel-Landau (VHL) E3 ligase-based BET PROTAC degrader. ARV-771 potently degrades BET protein in castration-resistant prostate cancer (CRPC) cells with a DC50 <1 nM.
价 格：￥电议型 号：T7752产 地：中国大陆
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T772301-O-Hexadecyl-2-O-docosahexaenoyl-sn-glycero-3-phosphorylcholine；化合物 1-O-Hexadecyl-2-O-docosahexaeno
1-O-Hexadecyl-2-O-docosahexaenoyl-sn-glycero-3-phosphorylcholine, an endogenous metabolite found in urine, has applications in obesity research [1] [2].
价 格：￥电议型 号：T77230产 地：中国大陆
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T76465Biotinyl-Ahx-Amyloid β-Protein (1-42) (ammonium)；化合物 Biotinyl-Ahx-Amyloid β-Protein (1-42) (ammonium
Biotinyl-Ahx-Amyloid β-Protein (1-42) ammonium is an N-terminally biotin-tagged form of Amyloid β-Protein (1-42), which constitutes the main component of vascular and parenchymal amyloid deposits associated with Alzheimer´s disease [1].
价 格：￥电议型 号：T76465产 地：中国大陆
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T76125Creatininase；肌酐酶CAH|||Creatinine amidohydrolase；CAH|||Creatinine amidohydrolase
Creatininase (CAH) is a homohexameric enzyme found in Pseudomonas putida, which can be used in the study of biosensors for creatinine assays and chronic renal failure.
价 格：￥电议型 号：T76125产 地：中国大陆
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T76080LHuman PD-L1 inhibitor V TFA；化合物 Human PD-L1 inhibitor V TFAHuman PD-L1 inhibitor V TFA
Human PD-L1 Inhibitor V TFA, a peptide that binds to the human PD-1 protein, exhibits a dissociation constant (Kd) of 3.32 μM and effectively inhibits the hPD-1/hPD-L1 interaction [1].
价 格：￥电议型 号：T76080L产 地：中国大陆
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T76074HIV Protease Substrate 1 TFA；化合物 HIV Protease Substrate 1 TFAHIV Protease Substrate 1 TFA
HIV Protease Substrate 1 TFA, a fluorogenic substrate for HIV protease, facilitates the investigation of the enzyme´s activity [1].
价 格：￥电议型 号：T76074产 地：中国大陆
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T76059SAH-SOS1A TFA；SAH-SOS1A TFASAH-SOS1A TFA
SAH-SOS1A TFA is a peptide-based SOS1/KRAS protein interaction inhibitor. SAH-SOS1A TFA binds to wild-type and mutant KRAS (G12D, G12V, G12C, G12S, and Q61H) with nanomolar affinity ( EC 50 =106-175 nM). SAH-SOS1A TFA directly and independently blocks nucleotide association. SAH-SOS1A TFA impairs KRAS-driven cancer cell viability and exerts its effects by on-mechanism blockade of the ERK-MAPK phosphosignaling cascade downstream of KRAS [1] .
价 格：￥电议型 号：T76059产 地：中国大陆
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T76054SAHM1 TFA；化合物 SAHM1 TFASAHM1 TFA
SAHM1 TFA is a chemical compound that acts as a Notch pathway inhibitor by stabilizing a hydrocarbon-stapled alpha helical peptide. It specifically targets the protein-protein interface, effectively preventing the assembly of the Notch complex.
价 格：￥电议型 号：T76054产 地：中国大陆
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T7598Calcium N5-methyltetrahydrofolate；N5-甲基四氢叶酸钙NSC173328；5-甲基四氢叶酸钙|||N5-甲基四氢叶酸钙|||NSC173328
Calcium N5-methyltetrahydrofolate (NSC-173328) is the calcium salt of levomefolic acid, which has been proposed for treatment of cardiovascular disease and advanced cancers such as breast and colorectal cancers
价 格：￥电议型 号：T7598产 地：中国大陆
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T75856Huwentoxin-IV TFA；化合物 Huwentoxin-IV TFAHuwentoxin-IV TFA
Huwentoxin-IV TFA is a potent, selective blocker of sodium channels, specifically inhibiting neuronal Nav1.7, Nav1.2, Nav1.3, and Nav1.4 with IC50 values of 26, 150, 338, and 400 nM, respectively. It preferentially targets the peripheral nerve subtype Nav1.7 by interacting with neurotoxin receptor site 4, demonstrating analgesic effects in animal models of inflammatory and neuropathic pain [1] [2].
价 格：￥电议型 号：T75856产 地：中国大陆
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T75853HS014 TFA；化合物 HS014 TFAHS014 TFA
HS014 TFA, a potent and selective antagonist of the melanocortin-4 (MC4) receptor, exhibits K i values of 3.16, 108, 54.4, and 694 nM for the human MC4, MC1, MC3, and MC5 receptors, respectively. It effectively increases food intake in free-feeding rats [1] [2].
价 格：￥电议型 号：T75853产 地：中国大陆
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T75852HS024 TFA；化合物 HS024 TFAHS024 TFA
HS024, a selective MC4 receptor antagonist, exhibits affinity with Ki values of 0.29, 3.29, 5.45, and 18.6 nM for MC4, MC5, MC3, and MC1 receptors, respectively. This compound has been shown to increase food intake [1].
价 格：￥电议型 号：T75852产 地：中国大陆
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T75840Hemokinin 1, human TFA；化合物 Hemokinin 1, human TFAHemokinin 1, human TFA
Hemokinin 1, human TFA acts as a selective full agonist at the tachykinin neurokinin 1 (NK1) receptor, while also being a full agonist at NK2 and NK3 receptors. It is capable of inducing opioid-independent analgesia [1] [2].
价 格：￥电议型 号：T75840产 地：中国大陆
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T75835HSDVHK-NH2 TFA；化合物 HSDVHK-NH2 TFAHSDVHK-NH2 TFA
HSDVHK-NH2 TFA acts as an antagonist to the αvβ3-vitronectin integrin interaction, displaying an inhibitory concentration (IC 50) of 1.74 pg/mL (2.414 pM) [1] [2].
价 格：￥电议型 号：T75835产 地：中国大陆
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T75833HNGF6A TFA；化合物 HNGF6A TFAHNGF6A TFA
HNGF6A TFA, a humanin analogue, enhances glucose-stimulated insulin secretion and glucose metabolism, offering potential for diabetes research. It also inhibits ROS (Reactive Oxygen Species) production under oxidative stress and may prevent endothelial dysfunction and atherosclerosis in vivo [1] [2].
价 格：￥电议型 号：T75833产 地：中国大陆
