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T7147ValbenazineNBI98854,Valbenazine,disease,VMAT2,Monoamine Transporter,monoamine,transporter,NBI 98854,
Valbenazine, a highly selective vesicular monoamine transporter 2(VMAT2) inhibitor, is approved for the treatment of tardive dyskinesia.
价 格:¥电议型 号:T7147产 地:中国大陆
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T15117Didesmethyl cariprazineDidesmethyl cariprazine
Cariprazine is an antipsychotic drug candidate. It shows high affinity for the D3 and D2 receptors, and moderate affinity for the 5-HT1A receptor. Didesmethyl cariprazine is a metabolite of Cariprazine and acts as the predominant circulating active moiety.
价 格:¥电议型 号:T15117产 地:中国大陆
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T63603-deazaneplanocin A HCl
3-deazaneplanocin A HCl is both an S-adenosyl-l-homocysteine hydrolase inhibitor and an enhancer of zeste homolog 2(EZH2) inhibitor.
价 格:¥电议型 号:T6360产 地:中国大陆
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T6318AZ 628
AZ628 is a new pan-Raf inhibitor for BRAF, BRAFV600E, and c-Raf-1 with IC50 of 105 nM, 34 nM and 29 nM, also inhibits VEGFR2, DDR2, Lyn, Flt1, FMS, etc.
价 格:¥电议型 号:T6318产 地:中国大陆
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T6309AZ960AZ 960
AZ 960 is an effective ATP competitive JAK2 inhibitor (IC50/Ki: <3 nM and0.45 nM).
价 格:¥电议型 号:T6309产 地:中国大陆
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T6257AZ191
AZ191(IC50 of 17 nM) is an effective and specific DYRK1B inhibitor. The specificity of AZ191 for DYRK1B is about 5- and 110-fold greater over DYRK1A and DYRK2, respectively.
价 格:¥电议型 号:T6257产 地:中国大陆
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T6253Talazoparib他拉唑帕利;BMN-673;LT-673
Talazoparib is a new-type PARP inhibitor (IC50: 0.58 nM), It similarly binds to PARP1/2 (Kis: 1.2/0.85 nM).
价 格:¥电议型 号:T6253产 地:中国大陆
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T6232Vilazodone Hydrochloride盐酸维拉佐酮;EMD 68843;Vilazodone HCl;SB659746A
Vilazodone HCl, a partial agonist of 5-HT1A receptors and specific serotonin reuptake inhibitor (SSRI), is utilized in treating of the major depressive disorder.
价 格:¥电议型 号:T6232产 地:中国大陆
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T6219Azilsartan Medoxomil阿齐沙坦酯;TAK-491
Azilsartan medoxomil(TAK 491) is an orally administered angiotensin II receptor type 1 antagonist with IC50 of 0.62 nM, which used in the treatment of adults with essential hypertension.
价 格:¥电议型 号:T6219产 地:中国大陆
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T6218SelumetinibARRY-142886;AZD6244;司美替尼
Selumetinib (AZD6244) is an effective, specific inhibitor of MEK1 and ERK1/2 phosphorylation (IC50: 14/10 nM).
价 格:¥电议型 号:T6218产 地:中国大陆
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T6211PosaconazoleSCH 56592;POS;泊沙康唑
Posaconazole is a sterol C14ɑ demethylase inhibitor (IC50: 0.25 nM).
价 格:¥电议型 号:T6211产 地:中国大陆
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T6135YO-01027二苯并氮卓;DBZ;gamma-Secretase Inhibitor XX;Dibenzazepine
YO-01027 is a potent γ-secretase inhibitor.
价 格:¥电议型 号:T6135产 地:中国大陆
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T6120Pralatrexate10-炔丙基-10-去氮杂氨基蝶呤;普拉曲沙;10-Propargyl-10-deazaaminopterin;Folotyn
Pralatrexate is a folate analogue inhibitor of dihydrofolate reductase (DHFR) exhibiting high affinity for reduced folate carrier-1 (RFC-1) with antineoplastic and immunosuppressive activities.
价 格:¥电议型 号:T6120产 地:中国大陆
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T6093AZD-7762AZD7762
AZD7762, an effective and specific inhibitor of Chk1(IC50=5 nM), is equally potent against Chk2 and less potent against CAM, Yes, Fyn, Lyn, Hck and Lck.
价 格:¥电议型 号:T6093产 地:中国大陆
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T6092SapitinibAZD-8931;沙普替尼
AZD8931, a reversible, ATP competitive inhibitor of EGFR(IC50=4 nM), ErbB2(IC50=3 nM) and ErbB3(IC50=4 nM), is more effective over Gefitinib or Lapatinib against NSCLC cell, 100-fold more specific for the ErbB family over MNK1 and Flt.
价 格:¥电议型 号:T6092产 地:中国大陆
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T6087AZD 6482KIN 193;AZD6482
AZD 6482 is a potent and selective p110β inhibitor with IC50 of 0.69 nM and a PI3Kβ inhibitor with IC50 of 10 nM.
价 格:¥电议型 号:T6087产 地:中国大陆
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T6083AZD8330ARRY-424704;ARRY-704
AZD8330 is a novel, selective, non-ATP competitive MEK 1/2 inhibitor with IC50 of 7 nM. Phase 1.
价 格:¥电议型 号:T6083产 地:中国大陆
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T6078SaracatinibAZD0530;塞卡替尼
Saracatinib (AZD0530) is an effective Src inhibitor (IC50: 2.7 nM), and effective to Lck, Fyn, Lyn, Blk, Fgr and c-Yes.
价 格:¥电议型 号:T6078产 地:中国大陆
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T6071ParbendazoleSKF 29044;帕苯咪唑
Parbendazole is a potent inhibitor of microtubule assembly(EC50 : 8.79 nM).Parbendazole is a carbamate ester-amine. It finds applications in control or treatment of nematode infestations.
价 格:¥电议型 号:T6071产 地:中国大陆
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T60001Benzamide, 3-methoxy-N-(3-thiazolo[5,4-b]pyridin-2-ylphenyl)
Benzamide, 3-methoxy-N-(3-thiazolo[5,4-b]pyridin-2-ylphenyl) is a sirtuin modulator and useful for increasing the lifespan of a cell, and treating and?/or preventing a wide variety of diseases and disorders including diabetes, cardiovascular disease, bloo
价 格:¥电议型 号:T60001产 地:中国大陆