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T80930TRPV2-selective blocker 1;化合物 TRPV2-selective blocker 1TRPV2-selective blocker 1
TRPV2-selective blocker 1 (compound IV2-1) is a selective inhibitor of the TRPV2 channel, exhibiting an IC50 value of 6.3 μM. It specifically targets the TRPV2 channel without impacting related TRPV1, TRPV3, or TRPV4 channels. Additionally, this compound effectively suppresses TRPV2-mediated calcium influx in macrophages and inhibits their phagocytic activity [1].
价 格:¥电议型 号:T80930产 地:中国大陆
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T80607Eblasakimab;化合物 EblasakimabCSL-334|||ASLAN004;CSL-334|||ASLAN004
Eblasakimab (also known as ASLAN004 or CSL-334) is a human IgG4 monoclonal antibody that selectively binds to IL13RA1, and is predominantly produced in CHO-K1 cells [1].
价 格:¥电议型 号:T80607产 地:中国大陆
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T79900Cbl-b-IN-13;化合物 Cbl-b-IN-13Cbl-b-IN-13
Cbl-b-IN-13 (Example 520) is a potent Cbl-b inhibitor exhibiting an IC50 of less than 100 nM and is capable of activating T-cells [1].
价 格:¥电议型 号:T79900产 地:中国大陆
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T79899Cbl-b-IN-12;化合物 Cbl-b-IN-12Cbl-b-IN-12
Cbl-b-IN-12 (Example 10) is an inhibitor of casitas B-lineage lymphoma-b (CBL-B), demonstrating a half-maximal inhibitory concentration (IC50) of less than 100 nM [1].
价 格:¥电议型 号:T79899产 地:中国大陆
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T79898Cbl-b-IN-11;化合物 Cbl-b-IN-11Cbl-b-IN-11
Cbl-b-IN-11 (Compound 466) is an inhibitor of both casitas B-lineage lymphoma-b (Cbl-b) and c-Cbl, exhibiting half-maximal inhibitory concentrations (IC50s) of 6.4 nM and 6.1 nM, respectively [1].
价 格:¥电议型 号:T79898产 地:中国大陆
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T79897Cbl-b-IN-10;化合物 Cbl-b-IN-10Cbl-b-IN-10
Cbl-b-IN-10 (Compound 463) is a potent inhibitor of both casitas B-lineage lymphoma-b (Cbl-b) and c-Cbl, exhibiting half-maximal inhibitory concentrations (IC50s) of 6.0 nM and 3.5 nM, respectively [1].
价 格:¥电议型 号:T79897产 地:中国大陆
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T79896Cbl-b-IN-9;化合物 Cbl-b-IN-9Cbl-b-IN-9
Cbl-b-IN-9 (Compound 300) is an inhibitor targeting casitas B-lineage lymphoma-b (Cbl-b) and c-Cbl, exhibiting potent inhibitory activity with half-maximal inhibitory concentrations (IC50s) of 5.6 nM and 4.7 nM, respectively [1].
价 格:¥电议型 号:T79896产 地:中国大陆
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T79895Cbl-b-IN-8;化合物 Cbl-b-IN-8Cbl-b-IN-8
Cbl-b-IN-8 (Compound 293) is an inhibitor of both casitas B-lineage lymphoma-b (Cbl-b) and c-Cbl, exhibiting half maximal inhibitory concentrations (IC50s) of 5.5 nM and 7.8 nM, respectively [1].
价 格:¥电议型 号:T79895产 地:中国大陆
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T79894Cbl-b-IN-7;化合物 Cbl-b-IN-7Cbl-b-IN-7
Cbl-b-IN-7 (Compound 248) is an inhibitor of casitas B-lineage lymphoma-b (Cbl-b) and c-Cbl, exhibiting inhibitory half-maximal inhibitory concentrations (IC50s) of 6.7 nM and 5.2 nM, respectively [1].
价 格:¥电议型 号:T79894产 地:中国大陆
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T79893Cbl-b-IN-6;化合物 Cbl-b-IN-6Cbl-b-IN-6
Cbl-b-IN-6 (Compound 246) is an inhibitor of both casitas B-lineage lymphoma-b (Cbl-b) and c-Cbl, exhibiting inhibitory half-maximal inhibitory concentrations (IC50s) of 6.7 nM for Cbl-b and 5.2 nM for c-Cbl, respectively [1].
价 格:¥电议型 号:T79893产 地:中国大陆
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T79853Lerzeparib;化合物 LerzeparibLerzeparib
Lerzeparib is a PARP (ADP-ribose polymerase) inhibitor that exhibits antineoplastic activity [1].
价 格:¥电议型 号:T79853产 地:中国大陆
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T79851Labuxtinib;LabuxtinibLabuxtinib
Labutinib is a selective inhibitor of the c-kit tyrosine kinase [1].
价 格:¥电议型 号:T79851产 地:中国大陆
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T79785Laxiflorin B;化合物 Laxiflorin BLaxiflorin B
Laxiflorin B, a novel selective inhibitor of ERK 1/2 derived from herbal sources, exhibits antitumor activity [1].
价 格:¥电议型 号:T79785产 地:中国大陆
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T79716c-ABL-IN-5;化合物 c-ABL-IN-5c-ABL-IN-5
C-ABL-IN-5, a selective c-Abl inhibitor, exhibits neuroprotective properties and has favorable characteristics including blood-brain barrier permeability, metabolic stability, and pharmacokinetic profiles. When labeled with [18F] (compound [18F]3), C-ABL-IN-5 serves as a tracer in positron emission tomography (PET) scans to assess disease-modifying effects, particularly in research on neurodegenerative conditions like Parkinson´s disease (PD) [1].
价 格:¥电议型 号:T79716产 地:中国大陆
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T79418BLT2 antagonist-1;化合物 BLT2 antagonist-1BLT2 antagonist-1
BLT2 antagonist-1 (compound 15b) is a selective inhibitor of the BLT2 receptor, impeding the chemotaxis of CHO-BLT2 cells at an IC50 of 224 nM, while not affecting CHO-BLT1 cell chemotaxis. It blocks the interaction between LTB4 and the BLT2 receptor with a K_i of 132 nM and may serve as a research tool for inflammatory airway diseases, including asthma and chronic obstructive pulmonary disease [1].
价 格:¥电议型 号:T79418产 地:中国大陆
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T79317MBL-IN-1;化合物 MBL-IN-1MBL-IN-1
MBL-IN-1 (compound 41), a β-Lactamase inhibitor, exhibits an IC50 range of 0.10 to 25.85 ?M and is utilized in the study of bacterial infections [1].
价 格:¥电议型 号:T79317产 地:中国大陆
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T78603Sotuletinib dihydrochloride;化合物 Sotuletinib dihydrochlorideBLZ945 dihydrochloride;BLZ945 dihydrochlo
Sotuletinib (BLZ945) dihydrochloride is an orally administered, blood-brain barrier-permeable inhibitor specifically targeting CSF1-R with an IC50 of 1 nM. It promotes apoptosis in tumor cells and significantly restricts tumor growth in murine models, proving useful in cancer and amyotrophic lateral sclerosis (ALS) studies [1].
价 格:¥电议型 号:T78603产 地:中国大陆
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T78453Fast Blue B Salt;固兰BFast Blue B Salt
Fast Blue B Salt, a fat-soluble and phenolic compound-binding dye, serves for semi-quantitative analysis of alkylresorcinols in rye and forms a colored precipitate upon acetone exposure [1]. It also demonstrates affinity for diazonium compounds.
价 格:¥电议型 号:T78453产 地:中国大陆
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T78451Patent Blue V;专利蓝VF ;酸性蓝1,食品蓝3;食品蓝 3Acid blue 1;Acid blue 1
Patent Blue V (Acid blue 1), a biological dye, serves as an intraocular stain in retinectomy—surgical removal of the inner limiting membrane (ILM). Its use facilitates the complete excision of premembrane structures in vitreoretinal surgeries. Spectral analysis reveals that Patent Blue V absorbs strongly below 450 nm and above 600 nm, exhibiting a blue-green hue. Additionally, it functions as a tracer in lymphangiography to guide the surgical removal of cancerous lymph nodes [1][2].
价 格:¥电议型 号:T78451产 地:中国大陆
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T78322Lesabelimab;化合物 LesabelimabLDP;LDP
Lesabelimab (LDP) is an anti-CD274 monoclonal antibody of the immunoglobulin G1-kappa subclass. It targets CD274, an immune checkpoint ligand that suppresses antitumor immunity by engaging with the PDCD1 receptor [1] [2].
价 格:¥电议型 号:T78322产 地:中国大陆