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T37955Sphingosine-1-phosphate (d16:1)；Sphingosine-1-phosphate (d16:1)Sphingosine-1-phosphate (d16:1)；Sphin
C16 Sphingosine-1-phosphate (C16 S1P) is a derivative of sphingosine-1-phosphate that binds to S1P1/EDG-1, S1P3/EDG-3, and S1P2/EDG-5 receptors with affinities of 115%, 83%, and 103%, respectively, relative to S1P in CHO cells. C16 S1P was increased in postmortem primary open angle glaucoma trabecular meshwork samples.
价 格：￥电议型 号：T37955产 地：中国大陆
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T37954Sphingosine (d20:1)；Sphingosine (d20:1)Sphingosine (d20:1)；Sphingosine (d20:1)
Sphingosines are long-chain base precursors of cellular sphingolipids used directly in the synthesis of ceramide, which in combination with sialic acid forms ganglioside. Sphingosine can exist in four stereoisomers, however only sphingosine occurs naturally. Compared to other sphingolipids throughout the body, which are predominantly composed of C-18 sphingosine, only central nervous system (CNS) gangliosides contain significant amounts of sphingosine. The concentration of sphingosine within mam
价 格：￥电议型 号：T37954产 地：中国大陆
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T37953Sphingomyelins (buttermilk)；Sphingomyelins (buttermilk)Sphingomyelins (buttermilk)
Sphingomyelins (SMs) are bioactive sphingolipids found in mammalian cell membranes.1SMs make up 2-15% of the total organ phospholipid population but are found at higher concentrations in the brain and myelin sheaths surrounding peripheral nerves. They interact with cholesterol to control its distribution within cellular membranes and maintain cholesterol homeostasis in cells. SMs undergo hydrolysis by sphingomyelinase to form ceramides, which are sphingolipid mediators of intracellular signaling
价 格：￥电议型 号：T37953产 地：中国大陆
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T37952Sphinganine-1-phosphate (d17:0)；Sphinganine-1-phosphate (d17:0)Sphinganine-1-phosphate (d17:0)；Sphin
Sphinganine-1-phosphate (d17:0) is a sphingolipid analog of sphinganine-1-phosphate (d18:0) and sphingosine-1-phosphate (d18:1) that has a 17-carbon base. Sphinganine-1-phosphate (d17:0) levels are lower in surgical and cadaver trabecular meshwork samples isolated from patients with primary open angle glaucoma compared with control samples.
价 格：￥电议型 号：T37952产 地：中国大陆
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T3792813C6 Glucosylsphingosine (d18:1)；13C6 Glucosylsphingosine (d18:1)13C6 Glucosylsphingosine (d18:1)
13C6 Glucosylsphingosine (d18:1) is an isotopically enriched form of 1-β-D-glucosylsphingosine (d18:1) that is intended for use as an internal standard for the quantification of 1-β-D-glucosylsphingosine by GC- or LC-MS. 1-β-D-Glucosylsphingosine is a lysolipid derivative of glucosylcerebroside that decreases activity of glucocerebrosidase in LA-N-2 cells in a dose-dependent manner.
价 格：￥电议型 号：T37928产 地：中国大陆
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T3789Ophiopogonin B；麦冬皂苷 BOphiopogonin B
Ophiopogonin B has antitumor activity and is a prospective inhibitor of PI3K/Akt.
价 格：￥电议型 号：T3789产 地：中国大陆
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T37809AlphitoninAlphitoninAlphitonin
Alphitonin is a flavonoid that has been found in L. leptolepis wood.1 It is also a metabolic intermediate that is formed during the catabolism of quercetin by the human gut bacteria E. ramulus.2,3
价 格：￥电议型 号：T37809产 地：中国大陆
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T37562C16 Ceramide；N-棕榈酰神经鞘氨醇N-acylsphingosine|||C16 Ceramide (d18:1/16:0)|||Palmitoyl Ceramide|||N-Palmit
C16 Ceramide (Palmitoyl Ceramide) is a naturally occurring small molecule that activates p53 by directly and selectively binding to it.
价 格：￥电议型 号：T37562产 地：中国大陆
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T37544Anhydroophiobolin A；Anhydroophiobolin AAnhydroophiobolin A
Anhydroophiobolin A is an ophiobolin fungal metabolite that has been found in C. heterostrophus fermentation broths. It is cytotoxic to HepG2 and K562 cancer cells (IC50s = 55.7 and 39.5 μM, respectively).
价 格：￥电议型 号：T37544产 地：中国大陆
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T37543Anhydroepiophiobolin A；Anhydroepiophiobolin AAnhydroepiophiobolin A
Anhydroepiophiobolin A is a sesterterpenoid fungal metabolite that has been found in B. oryzae. It is cytotoxic to HepG2 and K562 cells (IC50s = 47.1 and 35.6 μM, respectively) as well as A549, SKOV3, SK-MEL-2, XF498, and HCT15 cells (IC50s = 1.6-1.9 μg/ml). Anhydroepiophiobolin A is phytotoxic to S. viridis and D. erucoides in a leaf puncture assay.
价 格：￥电议型 号：T37543产 地：中国大陆
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T37478Acetyl β-Endorphin (1-26) (human) (trifluoroacetate salt)；Acetyl β-Endorphin (1-26) (human) (trifluo
Acetyl β-endorphin (1-26) is a neuropeptide found in rat hippocampus, brain stem, and pituitary. It is also present in the human hypothalamus, where it comprises approximately 4.9% of total β-endorphin peptides. Acetyl β-endorphin (1-26) is produced through posttranslational processing of β-endorphin and is processed similarly in rat and human hypothalamus. Levels of acetyl β-endorphin (1-26) increase in the rat pars intermedia and brain stem following chronic administration of haloperidol .
价 格：￥电议型 号：T37478产 地：中国大陆
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T37436C12-Ceramide；化合物 C12-CeramideN-Laurylsphingosine|||C12 Ceramide (d18:1/12:0)|||N-Lauroyl-D-erythro-s
C12-Ceramide (C12 Ceramide (d18:1/12:0)), a ceramide present in the protective membranes surrounding umbilical cord blood vessels in infants born to women with pre-eclampsia, can be used to assess the level of ASM activity in the plasma of patients with Niemann-Pick disease.
价 格：￥电议型 号：T37436产 地：中国大陆
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T37187D-erythro/L-threo Lysosphingomyelin (d18:1)；D-erythro/L-threo Lysosphingomyelin (d18:1)D-erythro/L-t
Lysosphingomyelin is an endogenous bioactive sphingolipid and a constituent of lipoproteins.1,2It is produced by the removal of the acyl group from sphingomyelin by a deacylase and acts as a precursor in the biosynthesis of sphingosine-1-phosphate . D-erythroLysosphingomyelin is an agonist of the S1P receptors S1P1, S1P2, and S1P3(EC50s = 167.7, 368.1, and 482.6 nM, respectively, for the human receptors).3It is also an agonist of the orphan receptor ovarian cancer G protein-coupled receptor 1 (O
价 格：￥电议型 号：T37187产 地：中国大陆
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T37010D-threo Sphinganine (d18:0)；D-threo Sphinganine (d18:0)D-threo Sphinganine (d18:0)；D-threo Sphingani
D-threo Sphinganine (d18:0) is a synthetic bioactive sphingolipid and stereoisomer of sphinganine (d18:0) and L-erythro sphinganine (d18:0) . It induces autophagy in HCT116 cells when used at a concentration of 12 μM. D-threo Sphinganine (d18:0) is metabolized via sphinganine N-acyltransferase and sphinganine kinase in vivo in rat liver.
价 格：￥电议型 号：T37010产 地：中国大陆
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T37009Oxychlororaphine；吩嗪-1-甲酰胺phenazine-1-carboxamide；吩嗪-1-甲酰胺|||phenazine-1-carboxamide
Oxychlororaphine (phenazine-1-carboxamide) inhibits strongly the growth of Streptomyces sp. 441.
价 格：￥电议型 号：T37009产 地：中国大陆
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T36987N,N-dimethyl Sphinganine (d18:0)；N,N-dimethyl Sphinganine (d18:0)N,N-dimethyl Sphinganine (d18:0)；N,
N,N-dimethyl Sphinganine (d18:0) is a sphingolipid that increases during development ofL. donovanipromastigotes.1
价 格：￥电议型 号：T36987产 地：中国大陆
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T36860C22 Sphingomyelin (d18:1/22:0)；C22 Sphingomyelin (d18:1/22:0)C22 Sphingomyelin (d18:1/22:0)；C22 Sphi
C22 Sphingomyelin is a naturally occurring form of sphingomyelin . Plasma levels of C22 sphingomyelin positively correlate with hepatic steatosis severity in patients with chronic hepatitis C virus (HCV). C22 Sphingomyelin levels are decreased in T-47D mammary epithelial cells and increased in MDA-MB-231 breast cancer cells relative to C16 sphingomyelin .
价 格：￥电议型 号：T36860产 地：中国大陆
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T36722Deltorphin II (trifluoroacetate salt)；Deltorphin II (trifluoroacetate salt)Deltorphin II (trifluoroa
Deltorphin II is a peptide agonist of δ2-opioid receptors.1,2It is selective for δ-opioid receptors over μ- and κ-opioid receptors in radioligand bindings assays (Kis = 0.0033, >1, and >1 μM, respectively) and induces [35S]GTPγS binding in mouse brain membrane preparations (EC50= 0.034 μM). Deltorphin II (0.12 mg/kg) decreases the infarction zone:risk zone ratio in a rat model of myocardial ischemia-reperfusion injury induced by coronary occlusion, an effect that can be reversed by the δ2-opioid
价 格：￥电议型 号：T36722产 地：中国大陆
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T36613DL-erythro/threo Sphinganine (d16:0)；DL-erythro/threo Sphinganine (d16:0)DL-erythro/threo Sphinganin
DL-erythro/threo Sphinganine (d16:0) is a sphingolipid that is decreased in rats following long-term, low-dose administration of dimethoate and is used as a biomarker for dimethoate exposure. It has been found in the fermentation broth of Bacterium SRCnm, which has antimicrobial and antioxidant activities. This product is a mixture of sphinganine (d16:0), L-erythro sphinganine (d16:0), D-threo sphinganine (d16:0), and L-threo sphinganine (d16:0).
价 格：￥电议型 号：T36613产 地：中国大陆
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T36437Sphinganine (d17:0)；Sphinganine (d17:0)Sphinganine (d17:0)；Sphinganine (d17:0)
Sphinganine is a synthetic bioactive sphingolipid that inhibits the growth of C. glabrata and C. albicans with a minimum fungicidal concentration (MFC) value of 0.5 μg/ml for both. More commonly, sphinganine is used as an internal standard in the analysis of sphingoid compounds by chromatographic or spectrometric methods.
价 格：￥电议型 号：T36437产 地：中国大陆
