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T40109APOL1-IN-1;APOL1抑制剂1APOL1-IN-1;APOL1-IN-1
APOL1-IN-1 is a potent inhibitor of apolipoprotein L1 (APOL1) that can be used to study the pathogenesis of focal segmental glomerulosclerosis (FSGS) and nondiabetic kidney disease (NDKD), facilitating research into these diseases.
价 格:¥电议型 号:T40109产 地:中国大陆
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T3S2197Polygalic acid;远志皂甙Senegenic acid;Senegenic acid|||远志皂甙
Polygalic acid (Senegenic acid), a triterpenoid saponin, is a major active ingredient in Polygala tenuifolia. Polygalic acid shows expectorant, emetic and stimulant effects.
价 格:¥电议型 号:T3S2197产 地:中国大陆
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T39883Polyketide synthase 13-IN-1;Polyketide synthase 13-IN-1Polyketide synthase 13-IN-1
Polyketide synthase 13-IN-1 (compound 32) is a polyketide synthase 13 inhibitor.
价 格:¥电议型 号:T39883产 地:中国大陆
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T39822Polyoxin D;Polyoxin DPolyoxorim;Polyoxorim
Polyoxin D (Polyoxorim), a polyoxin antibiotic fungicide, effectively inhibits chitin synthetase.
价 格:¥电议型 号:T39822产 地:中国大陆
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T39693Polyketide synthase 13-IN-3;Polyketide synthase 13-IN-3Polyketide synthase 13-IN-3
Polyketide synthase 13-IN-3 (compound 41) is a potent inhibitor of polyketide synthase 13, demonstrating a minimum inhibitory concentration (MIC) range of 0.0625-0.125 μg/mL against the M. tuberculosis strain H37Rv.
价 格:¥电议型 号:T39693产 地:中国大陆
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T3915Ginsenoside Ro人参皂苷 Ro人参皂苷Ro|||Chikusetsusaponin 5|||Polysciasaponin P3|||人参皂苷 Ro|||Chikusetsusaponin
Ginsenoside Ro (Chikusetsusaponin V) can reduce TXA2 production, weakly reduce COX-1 and TXAS activities, and has antiplatelet effects as a Ca2+ antagonist with an IC50 of 155 μM.
价 格:¥电议型 号:T3915产 地:中国大陆
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T3895Polyphyllin I重楼皂苷I重楼皂苷I|||重楼皂甙
Polyphyllin D induces apoptosis via the mitochondrial apoptotic pathway as evidenced by decreased Bcl-2 expression levels, disruption of MMP and increased Bax, cytochrome C, and cleaved-caspase-3 levels. Polyphyllin D has an anti-angiogenic effect. Polyphyllin D has toxicity in human RBCs as well as its underlying mechanism for the hemolysis and eryptosis/erythroptosis. Polyphyllin D has strong anticancer activity, can overcome drug resistance in R-HepG2 cells and elicit programmed cell death vi
价 格:¥电议型 号:T3895产 地:中国大陆
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T3894Polyphyllin II;重楼皂苷 IIChonglou Saponin II;重楼皂苷 II|||Chonglou Saponin II
Polyphyllin II (Chonglou Saponin II) has hemostasis, expectorant, bacteriostasis, anticytotoxic, anti-pregnancy kill sperm effects.
价 格:¥电议型 号:T3894产 地:中国大陆
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T3888Scopolin东莨菪苷Murrayin|||东莨菪甙|||Scopoloside|||东莨菪苷
Scopolin (Scopoloside) formation is increased by the enhanced activity of PAL. Scopolin can reduce the clinical symptoms of rat AIA by inhibiting inflammation and angiogenesis, and this compound may be a potent agent for angiogenesis related diseases and can serve as a structural base for screening more potent synthetic analogs.
价 格:¥电议型 号:T3888产 地:中国大陆
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T3826Polygalasaponin F瓜子金皂苷己异牡荆苷|||瓜子金皂苷己
Polygalasaponin F has anti-neuroinflammatory activity, can inhibit the release of inflammatory cytokines TNF-α and NO induced by lipopolysaccharides (LPS) and reduce the expression of inducible nitric oxide synthases. Polygalasaponin F can significantly inhibit the cytotoxicity of conditioned medium prepared by LPS-stimulated BV-2 microglia (LPS conditioned media) to neuronal PC12 cells and improve cell viability. Polygalasaponin F can induce long-term potentiation in hippocampal dentate gyrus i
价 格:¥电议型 号:T3826产 地:中国大陆
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T3815Isoscopoletin;异莨菪亭7-Methoxyesculetin|||6-Hydroxy-7-methoxycoumarin;异莨菪亭|||7-Methoxyesculetin|||6-Hyd
Isoscopoletin (7-Methoxyesculetin) is a predicted metabolite generated by BioTransformer1 that is produced by the metabolism of 6, 7-dimethoxy-2h-chromen-2-one.
价 格:¥电议型 号:T3815产 地:中国大陆
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T3767Polygalacic acid;毛果一枝黄花皂苷元GVirgaureagenin G;Virgaureagenin G|||毛果一枝黄花皂苷元G|||远志酸
Polygalacic acid (Virgaureagenin G)(PA) significantly improves cholinergic system reactivity, as indicated by decreased acetylcholinesterase (AChE) activity, increases choline acetyltransferase (ChAT) activity, and elevates levels of acetylcholine (ACh) in the hippocampus and frontal cortex, PA also significantly ameliorates neuroinflammation and oxidative stress in mice; suggest that PA might exert a significant neuroprotective effect on cognitive impairment, driven in part by the modulation of
价 格:¥电议型 号:T3767产 地:中国大陆
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T37589GIP (3-42), human;GIP (3-42),人Gastric Inhibitory Polypeptide (3-42) (human);Gastric Inhibitory Polyp
GIP (3-42), human (Gastric Inhibitory Polypeptide (3-42) (human)) is a peptide that acts as a glucose-dependent proinsulinotropic polypeptide (GIP) receptor antagonist and regulates insulin secretion and the metabolic effects of GIP in vivo, which can be used to study type 2 diabetes.
价 格:¥电议型 号:T37589产 地:中国大陆
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T37588GIP (1-30) amide, porcine;Gastric Inhibitory Polypeptide (1-30) amide (porcine)GIP (1-30) amide, por
This GIP fragment has potent insulinotropic activity in the isolated, perfused rat pancreas but greatly reduced somatostatinotropic activity in the isolated perfused rat stomach. The site responsible for insulinotropic activity apparently lies between residues 19 and 30 of GIP.
价 格:¥电议型 号:T37588产 地:中国大陆
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T3717Hinokitiol;桧木醇4-Isopropyltropolone|||β-thujaplicin;4-Isopropyltropolone|||桧木醇|||β-thujaplicin|||β-桧木
Hinokitiol (4-Isopropyltropolone) can inhibit ultraviolet B-induced apoptosis in keratinocytes and strongly suggest that the inhibitory mechanism is due to the antioxidant activity of metallothionein induced by the agent. Also, Hinokitiol modulates estrogen receptor signaling and inhibits proliferation of human breast cancer cells.
价 格:¥电议型 号:T3717产 地:中国大陆
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T3696polygalaxanthone III;远志山酮IIIpolygalaxanthone III
Polygalaxanthone III can significantly inhibit chlorzoxazone 6-hydroxylation catalyzed by CYP2E1.
价 格:¥电议型 号:T3696产 地:中国大陆
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T35965MitoTEMPOLMitoTEMPOLMitoTEMPOL
MitoTEMPOL is a mitochondria-targeting superoxide dismutase mimetic that reduces mitochondrial O2- to H2O2. Like the related compound MitoTEMPO , MitoTEMPOL combines an antioxidant moiety (here, TEMPOL, also known as 4-hydroxy-TEMPO) with the lipophilic cation triphenylphosphonium, which allows it to pass through lipid bilayers and accumulate in mitochondria. MitoTEMPOL has been used to elucidate the role of mitochondria-derived superoxide in mitochondrial, cellular, and whole animal signaling.
价 格:¥电议型 号:T35965产 地:中国大陆
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T35317Zopolrestat;唑泊司他CP 73850|||CP73850|||CP-73850|||Zopolrestatum;CP 73850|||CP73850|||CP-73850|||唑泊司他||
Zopolrestat (CP 73850) is a potent inhibitor of aldose reductase (IC50 = 3.1 nM).
价 格:¥电议型 号:T35317产 地:中国大陆
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T3519Formosanin C;重楼皂苷BPolyphyllin B;Polyphyllin B|||重楼皂苷 B|||重楼皂苷B
Formosanin C (Polyphyllin B) is a compound isolated from Rhizoma Paridis, showed pro-apoptosis and immunoregulation with antitumor activity in cultured cells and animal systems.
价 格:¥电议型 号:T3519产 地:中国大陆
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T3493Clofentezine;四螨嗪Bisclofentazin|||Acaristop|||Apollo;Bisclofentazin|||Acaristop|||Apollo|||四螨嗪
Clofentezine (Apollo) is an active substance of plant protection product used as the pesticide, acaricide.
价 格:¥电议型 号:T3493产 地:中国大陆