T7846Aegelineαsyn,Aegeline,yeast,Inhibitor,protein,Sec22p,inhibit,toxicity,Fungal,SNARE

Aegeline is an alkaloidal-amide, isolated from the leaves of Aegle marmelos and have shown antihyperglycemic as well as antidyslipidemic activities in the validated animal models of type 2 diabetes mellitus.

价 格：￥电议型 号：T7846产 地：中国大陆

T6940PHA-767491 hydrochloridePHA767491,PHA 767491,inhibit,CAY-10572,Cyclin dependent kinase,CDK,CAY 10572

PHA-767491 is an effective ATP-competitive dual Cdc7/CDK9 inhibitor (IC50: 10/34 nM). It has ~20-fold selectivity against GSK3-β and CDK1/2, 50-fold selectivity against CDK5 and MK2, 100-fold selectivity against CHK2 and PLK1.

价 格：￥电议型 号：T6940产 地：中国大陆

T8423ML417neuroprotection,dopaminergic,β-arrestin,ML417,ML-417,translocation,phosphorylation,neurons,ML 4

ML417 is a selective and brain penetrant agonist of D3 Dopamine (EC50 : 38 nM).

价 格：￥电议型 号：T8423产 地：中国大陆

T8419XP-59XP 59,XP59,inhibit,Inhibitor,SARS-CoV,XP-59,SARS coronavirus

XP-59 is a potent the SARS-CoV Mpro inhibitor(Ki : 0.1 μM).

价 格：￥电议型 号：T8419产 地：中国大陆

T7117Sapropterin dihydrochloride(6R)-BH4,Sapropterin,Inhibitor,inhibit,Sapropterin dihydrochloride

Sapropterin dihydrochloride is phenylalanine hydroxylase agonist that is approved for the treatment of BH4 responsive PKU.

价 格：￥电议型 号：T7117产 地：中国大陆

T8478SC-43antiproliferative,Inhibitor,SC-43,SHP-1,PTPN6,Phosphatase,Apoptosis,caspase-3,SC 43,anti-fibrot

SC-43 is a potent and orally active agonist of SHP-1 (PTPN6). SC-43 inhibits the phosphorylation of STAT3 and induces cell apoptosis, and with anti-fibrotic and anticancer effects.

价 格：￥电议型 号：T8478产 地：中国大陆

T2573MisoprostolMisoprostol

价 格：￥电议型 号：T2573产 地：中国大陆

TP1240Adrenocorticotropic Hormone (ACTH) (18-39), human TFAinhibit,Adrenocorticotropic Hormone (ACTH) (18-

Adrenocorticotropic Hormone (ACTH) (18-39), human TFA is a corticotropinlike intermediate lobe peptide, it is is produced in the melanotrophs of the intermediate lobe of the pituitary.

价 格：￥电议型 号：TP1240产 地：中国大陆

T6566Levobupivacaine hydrochlorideCNS toxicity,gastric cancer,Na channels,Erastin,Inhibitor,analgesic,ana

Levobupivacaine HCl is a reversible neuronal sodium channel inhibitor, which is the pure S(-)-enantiomer of bupivacaine. It was utilized as a long-acting local anesthetic.

价 格：￥电议型 号：T6566产 地：中国大陆

T8678NaphthazarinNaturally,Apoptosis,Naphthazarin,stress,microtubules,mitochondrial,AIF,Inhibitor,p21,lys

Naphthazarin is effective by various cellular mechanisms including oxidative stress, activation of mitochondrial apoptosis-inducing factor (AIF), depolymerization of microtubules, interference with lysosomal function and p53-dependent p21 activation. It triggers apoptosis and has anti-tumor effects

价 格：￥电议型 号：T8678产 地：中国大陆

T7013VorapaxarProtease Activated Receptor (PAR),Inhibitor,SCH-530348,Vorapaxar,SCH530348,Thrombin recepto

Vorapaxar (SCH 530348) is an effective and orally active thrombin receptor (PAR-1) antagonist (Ki: 8.1 nM).

价 格：￥电议型 号：T7013产 地：中国大陆

T7265HSP27 inhibitor J2Heat shock proteins,inhibit,HSP-27 inhibitor J2,HSP27 inhibitor J2,Inhibitor,J 2,H

HSP27 inhibitor J2 (J2) is a HSP27 inhibitor, inhibits a production of HSP27 giant polymers, thereby having an effect of inhibiting a chaperone function of the HSP27 and reducing a cell protection function.

价 格：￥电议型 号：T7265产 地：中国大陆

TN7052Crocin IIIinhibit,Crocin III,Inhibitor

Crocin-3 is a crocin derived from saffron (Crocus sutivus L.). Crocins inhibit the cell growth of tumor cells and have anti-inflammatory activity.

价 格：￥电议型 号：TN7052产 地：中国大陆

TN3500beta-Amyroneantifungal,AChE,COX-2,PI3K-Akt,Anti-inflammatory,Fungal,β-Amyrone,inflammation,CHIKV,Cyc

beta-Amyrone has antifungal activity against Chikungunya virus replication with an EC50 of 86 uM. beta-Amyrone has anti-inflammatory activity through inhibiting the expression of COX-2. beta-Amyrone exhibits anti-α-glucosidase inhibitory activity and moderate AChE activity. β-Amyrone can be used in the research of disease like inflammation, infection, and obesity.

价 格：￥电议型 号：TN3500产 地：中国大陆

T13890SMARCA-BD ligand 1 for Protac dihydrochlorideSMARCABD ligand 1 for Protac dihydrochloride,SMARCA BD

SMARCA-BD ligand 1 for Protac dihydrochloride binds to the BAF ATPase subunits SMARCA2, and used for degrading SMARCA2, based on PROTAC.

价 格：￥电议型 号：T13890产 地：中国大陆

T8818TC-G 1005TC G 1005,G protein-coupled Bile Acid Receptor 1,levels,coupled,glucose,TCG 1005,Takeda,inh

TC-G 1005 is a potent and selective GPBA agonist (EC50 :0.72 nM; hTGR5). Selective for TGR5 over FXR (farnesoid X receptor). Increases plasma GLP-1 levels and reduces blood glucose in mice. Orally available.

价 格：￥电议型 号：T8818产 地：中国大陆

T10837Clocapramine dihydrochloride hydrateClocapramine dihydrochloride hydrate

Clocapramine dihydrochloride hydrate is an antagonist of the 5-HT2A and D2 receptors.

价 格：￥电议型 号：T10837产 地：中国大陆

T8617GMQ hydrochlorideGMQ hydrochloride

GMQ hydrochloride is a potent and selective acid-sensing ion channel (ASIC) modulator. It activates ASIC3 channels under neutral pH and blocks acid-induced maximal peak current.

价 格：￥电议型 号：T8617产 地：中国大陆

T8861GSK199GSK 199,GSK-199,GSK199,Inhibitor,Peptidylarginine Deiminase,Protein Arginine Deiminase,inhibit

GSK199 is a selective PAD4 inhibitor(IC50 of 200 nM in the absence of calcium).

价 格：￥电议型 号：T8861产 地：中国大陆

TQ027427-Hydroxycholesterol27Hydroxycholesterol,LXR,Liver X receptor,Inhibitor,Estrogen Receptor/ERR,Endog

27-Hydroxycholesterol is a selective modulator of estrogen receptor and an agonist of the liver X receptor.

价 格：￥电议型 号：TQ0274产 地：中国大陆