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  • T39222Mc-VC-PAB-SN38;化合物Mc-VC-PAB-SN38Mc-VC-PAB-SN38;Mc-VC-PAB-SN38

    Mc-VC-PAB-SN38 consists of a cleavable ADC linker (Mc-VC-PAB) and SN38, which is part of an antibody-coupled reactive molecule commonly used to synthesize antibody-coupled reactive molecules (ADCs) that target sites of action.

    价 格:¥电议型 号:T39222产 地:中国大陆

  • T38962MC-SN38;MC-SN38MC-SN38;MC-SN38

    MC-SN38 is a drug-linker conjugate that pairs the potent microtubule-disrupting agent SN38 with a non-cleavable MC linker, designed for use in antibody drug conjugates (ADCs). SN38, the active metabolite of the Topoisomerase I inhibitor Irinotecan, works by inhibiting DNA synthesis and inducing DNA single-strand breaks.

    价 格:¥电议型 号:T38962产 地:中国大陆

  • T38713Fmoc-L-Asn(beta-D-GlcNAc(Ac)3)-OH;Fmoc-L-Asn(beta-D-GlcNAc(Ac)3)-OHFmoc-Asn(Ac3AcNH-beta-Glc)-OH|||F

    Fmoc-L-Asn(beta-D-GlcNAc(Ac)3)-OH, also known as Fmoc-Asn(Ac3AcNH-beta-Glc)-OH, is a chemical compound used in the synthesis of silicon-fluoride acceptor (SiFA) derivatized octreotate derivatives. SiFA-octreotate analogues, which serve as tumor imaging agents, are valuable tools for positron emission tomography (PET) research.

    价 格:¥电议型 号:T38713产 地:中国大陆

  • T38474CL2-MMT-SN38;CL2-MMT-SN38CL2-MMT-SN38;CL2-MMT-SN38

    CL2-MMT-SN38 is a derivative of SN-38, which is a potent anticancer agent and the active metabolite of Irinotecan (CPT-11), a Topoisomerase I inhibitor.

    价 格:¥电议型 号:T38474产 地:中国大陆

  • T38460SN52;SN52SN52

    SN52 is a powerful, competitive, and cell-permeable inhibitor of NF-κB2. It is a variant of the SN50 peptide. SN52 effectively prevents the nuclear translocation of p52-RelB heterodimers, exhibiting a robust radiosensitization effect on prostate cancer cells. This compound holds significant potential for cancer research purposes.

    价 格:¥电议型 号:T38460产 地:中国大陆

  • T383561,2-Dipalmitoyl-13C-sn-glycero-3-PC;1,2-Dipalmitoyl-13C-sn-glycero-3-PC1,2-Dipalmitoyl-13C-sn-glycer

    1,2-Dipalmitoyl-13C-sn-glycero-3-PC is intended for use as an internal standard for the quantification of 1,2-dipalmitoyl-sn-glycero-3-PC by GC- or LC-MS. 1,2-Dipalmitoyl-sn-glycero-3-PC (DPPC) is a zwitterionic glycerophospholipid commonly used in the formation of lipid monolayers, bilayers, and liposomes for use in a variety of applications.1,2,3,4 It has been used in the formation of proteoliposomes for implantation of γ-glutamyl transpeptidase into human erythrocyte membranes.3 Incorporation

    价 格:¥电议型 号:T38356产 地:中国大陆

  • T382181-Stearoyl-2-docosahexaenoyl-sn-glycero-3-PC;化合物T382181-Stearoyl-2-docosahexaenoyl-sn-glycero-3-PC

    1-Stearoyl-2-docosahexaenoyl-sn-glycero-3-PC is a phospholipid in biological membranes containing stearic acid and docosahexaenoic acid at the sn-1 and sn-2 positions, respectively. It has been used to study the organization and dynamics of lipid membranes. In the superoxide dismutase 1 mutant transgenic mouse model of amyotrophic lateral sclerosis (ALS) 1-Stearoyl-2-docosahexaenoyl-sn-glycero-3-PC levels decrease in the anterior horn of L5 in late stages of the disease.1-Stearoyl-2-docosahexae

    价 格:¥电议型 号:T38218产 地:中国大陆

  • T382171-Stearoyl-2-Adrenoyl-sn-glycero-3-PE;1-Stearoyl-2-Adrenoyl-sn-glycero-3-PE1-Stearoyl-2-Adrenoyl-sn-

    1-Stearoyl-2-adrenoyl-sn-glycero-3-PE is a phospholipid that contains stearic acid and adrenic acid at thesn-1 andsn-2 positions, respectively. 1-Stearoyl-2-adrenoyl-sn-glycero-3-PE levels are inversely correlated with subject age in mitochondria isolated from human post-mortem hippocampus.1

    价 格:¥电议型 号:T38217产 地:中国大陆

  • T38012SNOB 1 ReagentSNOB 1 ReagentSNOB 1 Reagent

    SNOB 1 Reagent is a biotinylated probe for detecting S-nitrosylated proteins in a single step. S-Nitrosylated binding (SNOB) proceeds rapidly on surface proteins or cell lysates under normal physiological conditions. Proteins tagged with SNOB 1 Reagent can be analyzed using avidin-linked probes (e.g., by immunoblot) or by mass spectrometry.

    价 格:¥电议型 号:T38012产 地:中国大陆

  • T37776FASN-IN-4 tosylate;化合物 FASN-IN-4 tosylateFASN-IN-4 tosylate

    FASN-IN-4 tosylate is a potent fatty acid synthase (FASN) inhibitor, exhibiting an IC50 value of 10 nM. Additionally, it demonstrates inhibitory activity against SARS-CoV-2, with an EC50 of 18.6 nM [2].

    价 格:¥电议型 号:T37776产 地:中国大陆

  • T376231,2-Dierucoyl-sn-glycero-3-PC;1,2-Dierucoyl-sn-glycero-3-PC1,2-Dierucoyl-sn-glycero-3-PC

    1,2-Dierucoyl-sn-glycero-3-PC is a phospholipid containing erucic acid at the sn-1 and sn-2 positions. It has been used in the study of lipid membranes and to determine the effect of long-chain phospholipids on the secondary structure of human islet amyloid polypeptide (hIAPP).

    价 格:¥电议型 号:T37623产 地:中国大陆

  • T37553(-)-Mycousnine;(-)-Mycousnine(-)-Mycousnine

    (-)-Mycousnine is a microbial metabolite and derivative of usnic acid originally isolated fromM. nawaethat has antibacterial and antifungal activities.1,2It is active against the Gram-positive bacteriaB. subtilis,K. rhizophila, andS. aureus(MICs = 4, 8, and 4 g/ml, respectively) but not the Gram-negative bacteriaE. coli,S. typhimurium, andK. pneumoniae(MICs = >128 g/ml for all).2(-)-Mycousnine is also active against the fungiT. mentagrophytes,T. rubrum, andC. albicans(MICs = 25, 25, and 100 μg/m

    价 格:¥电议型 号:T37553产 地:中国大陆

  • T37502sn-Glycerol 3-phosphate lithium;sn-Glycerol 3-phosphate lithiumsn-Glycerol 3-phosphate lithium

    sn-Glycerol 3-phosphate lithium is synthesized via the cytosolic glycerol 3-phosphate dehydrogenase pathway. This process involves the conversion of dihydroxyacetone phosphate to sn-Glycerol 3-phosphate using NADH, which is generated during glycolysis.

    价 格:¥电议型 号:T37502产 地:中国大陆

  • T374871-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PE;1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PE1-Stearoyl-2-15(S)-

    1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PE is a phospholipid that contains stearic acid at the sn-1 position and 15(S)-HpETE at the sn-2 position. It is produced via oxidation of 1-stearoyl-2-arachidonoyl-sn-glycero-3-PE by 15-lipoxygenase (15-LO). 1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PE (0.6 and 0.9 μM) increases ferroptotic cell death in wild-type and Acsl4 knockout Pfa1 mouse embryonic fibroblasts (MEFs) treated with the GPX4 inhibitor RSL3.

    价 格:¥电议型 号:T37487产 地:中国大陆

  • T374861-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PC;1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PC1-Stearoyl-2-15(S)-

    1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PC is a phospholipid that contains stearic acid at the sn-1 position and 15(S)-HpETE at the sn-2 position. It is produced via oxidation of 1-stearoyl-2-arachidonoyl-sn-glycero-3-PC by 15-lipoxygenase (15-LO). 1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PC is toxic to human umbilical vein endothelial cells (HUVECs) when used at a concentration of 100 μM.

    价 格:¥电议型 号:T37486产 地:中国大陆

  • T374851-Stearoyl-2-15(S)-HETE-sn-glycero-3-PC;1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PC1-Stearoyl-2-15(S)-HE

    1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PC is a phospholipid that contains stearic acid at the sn-1 position and 15(S)-HETE at the sn-2 position. It is produced via oxidation of 1-stearoyl-2-arachidonoyl-sn-glycero-3-PC by 15-lipoxygenase (15-LO).

    价 格:¥电议型 号:T37485产 地:中国大陆

  • T37420Ac-ANW-AMC;Ac-ANW-AMCAc-ANW-AMC|||Ac-Ala-Asn-Trp-AMC;Ac-ANW-AMC|||Ac-Ala-Asn-Trp-AMC

    Ac-ANW-AMC is a fluorogenic substrate for the β5i/LMP7 subunit of the 20S immunoproteasome. [1] Upon cleavage, 7-amino-4-methylcoumarin (AMC) is released and its fluorescence can be used to quantify the activity of the β5i/LMP7 subunit of the 20S immunoproteasome. AMC displays excitation/emission maxima of 340-360/440-460 nm, respectively.

    价 格:¥电议型 号:T37420产 地:中国大陆

  • T372841-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE;1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE1-Stearoyl-2-15(S)-HE

    1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE is a phospholipid that contains stearic acid at the sn-1 position and 15(S)-HETE at the sn-2 position. It is formed in human peripheral monocytes activated by the calcium ionophore A23187 by direct oxidation of 1-stearoyl-2-arachidonoyl-sn-glycero-3-PE by 15-LO. Phosphoethanolamine (PE) HETEs (PE-HETEs), including 1-stearoyl-2-15(S)-HETE-sn-glycero-3-PE, are the main source of esterified HETE in ionophore-activated monocytes.

    价 格:¥电议型 号:T37284产 地:中国大陆

  • T371221,2-Dilinoleoyl-sn-glycerol;1,2-Dilinoleoyl-sn-glycerol1,2-Dilinoleoyl-sn-glycerol

    1,2-Dilinoleoyl-sn-glycerol is a diacylglycerol (DAG) with linoleic acid (18:2) side chains attached at both the sn-1 and sn-2 positions. It has been found as a component of phosphatidic acid in rat liver mitochondria and in spinach chloroplast membranes. 1,2-Dilinoleoyl-sn-glycerol is upregulated in some pregnant women and has been used as a biomarker to predict later preeclampsia in early pregnancy.

    价 格:¥电议型 号:T37122产 地:中国大陆

  • T370431,2-Dihexadecyl-sn-glycero-3-PC;1,2-Dihexadecyl-sn-glycero-3-PC1,2-Dihexadecyl-sn-glycero-3-PC

    1,2-Dihexadecyl-sn-glycero-3-PC can be used in related research in the field of life sciences. Its product number is T37043 and CAS number is 36314-47-3.

    价 格:¥电议型 号:T37043产 地:中国大陆

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