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T11347G6PD activator AG1；化合物 T11347G6PD activator AG1
G6PD activator AG1 is a glucose-6-phosphate dehydrogenase (G6PD) activator with an EC50 of 3 μΜ.
价 格：￥电议型 号：T11347产 地：中国大陆
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T11292FKBP12 PROTAC dTAG-7；化合物 T11292dTAG-7；dTAG-7
FKBP12 PROTAC dTAG-7 (dTAG-7) is a heterobifunctional compound that selectively degrades the BET bromodomain transcriptional co-activator BRD4 by connecting BET bromodomains to the E3 ubiquitin ligase CRBN. Additionally, it serves as a degrader of FKBP12F36V when FKBP12F36V is expressed in-frame with a targeted protein.
价 格：￥电议型 号：T11292产 地：中国大陆
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T11291FKBP12 PROTAC dTAG-13；化合物 T11291dTAG-13；dTAG-13
FKBP12 PROTAC dTAG-13 (dTAG-13) is a degrader of FKBP12F36V with expression of FKBP12F36V in-frame with a protein of interest. FKBP12 PROTAC dTAG-13 (dTAG-13) also is a selective degrader of BET bromodomain transcriptional co-activator BRD4 by bridging BET bromodomains to an E3 ubiquitin ligase CRBN. FKBP12 PROTAC dTAG-13 (dTAG-13) is a PROTAC-based heterobifunctional degrader.
价 格：￥电议型 号：T11291产 地：中国大陆
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T11237Camizestrant；化合物CamizestrantEstrogen receptor antagonist 2；Estrogen receptor antagonist 2
Camizestrant (Estrogen receptor antagonist 2) is an antagonist of the estrogen receptor and can be used in studies about ER+ HER2-advanced breast cancer[1].
价 格：￥电议型 号：T11237产 地：中国大陆
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T11236Giredestrant tartrate；Giredestrant酒石酸盐Estrogen receptor antagonist 1；Estrogen receptor antagonist 1
Giredestrant tartrate (Estrogen receptor antagonist 1) is a novel, orally active, selective and effective non-steroidal estrogen receptor antagonist. Giredestrant tartrate strongly binds to ER, resulting in the failure of ER to activate the transcription of targeted genes and promoting the degradation of ER protein. Giredestrant tartrate can be used to treat tumor diseases.
价 格：￥电议型 号：T11236产 地：中国大陆
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T11231ERRγ Inverse Agonist 1；化合物 T11231ERRγ Inverse Agonist 1
ERRγ Inverse Agonist 1 (Compound 12) is a potent, selective and orally bioavailable Estrogen-related Receptor grammar (ERRγ) inverse agonist (IC 50=40 nM) [1].
价 格：￥电议型 号：T11231产 地：中国大陆
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T11230ERRα antagonist-1；化合物ERRα 拮抗剂-1ERR+/- antagonist-1|||ERRa antagonist-1；ERR+/- antagonist-1|||ERRa an
ERRα antagonist-1 (ERR+/- antagonist-1) is a high-affinity, selective antagonist of the estrogen-related receptor α (ERRα). It effectively prevents the interaction of ERRα with both Proliferator-activated Receptor γ Coactivator-1α (PGC-1α) and PGC-1β, displaying IC50 values of 170 nM and 180 nM, respectively. Notably, ERRα antagonist-1 does not interfere with the interactions involving ERRβ or ERRγ and the PGC-1α and PGC-1β coactivators. Furthermore, it does not affect the interaction between ei
价 格：￥电议型 号：T11230产 地：中国大陆
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T11211EP4 receptor antagonist 1；化合物EP4 receptor antagonist 1EP4 receptor antagonist 1
EP4 Receptor Antagonist 1 is a highly potent and selective competitive prostanoid EP4 receptor antagonist, effective for cancer immunotherapy. It inhibits both human and mouse EP4 receptors with IC50 values of 6.1 nM and 16.2 nM, respectively, while displaying minimal activity (IC50s >10 μM) against human EP1, EP2, and EP3 receptors.
价 格：￥电议型 号：T11211产 地：中国大陆
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T1119Rasagiline；雷沙吉兰AGN1135|||TVP1012；雷沙吉兰|||AGN1135|||TVP1012
Rasagiline (AGN1135) is an inhibitor of monamine oxidase used as adjunctive therapy in combination with levodopa and carbidopa in the management of Parkinsons disease.
价 格：￥电议型 号：T1119产 地：中国大陆
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T11174(R)-Elagolix；恶拉戈利NBI-56418；恶拉戈利|||NBI-56418
(R)-Elagolix (NBI-56418) is a short-acting, nonpeptide, GnRH antagonist with an IC50 and Ki of 0.25 and 3.7 nM, respectively. administered orally, that unlike injectable depot GnRH agonists and antagonists, produces a dose-dependent suppression of ovarian estrogen production, that is, from partial suppression at lower doses to full suppression at higher doses.
价 格：￥电议型 号：T11174产 地：中国大陆
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T11137(E)-GABAB receptor antagonist 1；(E)-GABAB受体拮抗剂-1(E)-GABAB receptor antagonist 1
(E)-GABAB receptor antagonist 1 is a trans-GABAB receptor antagonist 1. (E)-GABAB receptor antagonist 1 decreases GABA-induced IP3 (inositol trisphosphate) production with IC50 of 37.9 μM. GABAB receptor antagonist 1 is a selective and negative allosteric modulator of GABAB (γ-Aminobutyric acid) receptors.
价 格：￥电议型 号：T11137产 地：中国大陆
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T11095LDREADD agonist 21；化合物DREADD agonist 21DREADD agonist 21
DREADD agonist 21 is a potent agonist of human muscarinic acetylcholine M3 receptors (EC50=1.7 nM).
价 格：￥电议型 号：T11095L产 地：中国大陆
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T11095DREADD agonist 21 dihydrochloride；化合物 T11095DREADD agonist 21 dihydrochloride (56296-18-5 free base)
DREADD agonist 21 dihydrochloride is a potent human muscarinic acetylcholine M3 receptors ( hM3Dq ) agonist with EC 50 of 1.7 nM [1].
价 格：￥电议型 号：T11095产 地：中国大陆
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T11077Dopamine D2 receptor antagonist-1；多巴胺D2受体拮抗剂-1Dopamine D2 receptor antagonist-1
Dopamine D2 Receptor Antagonist-1 functions as a negative allosteric modulator (NAM) of the dopamine D2 receptor (D2R), demonstrating sub-millimolar affinity.
价 格：￥电议型 号：T11077产 地：中国大陆
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T11035diABZI STING agonist-1 (Tautomerism)；化合物T11035diABZI STING agonist (Compound 3)；diABZI STING agonist
diABZI STING agonist-1 (Tautomerism) (diABZI STING agonist (Compound 3)) is a selective stimulator of interferon genes (STING) receptor agonist, with EC50s of 130, 186 nM for human and mouse, respectively.
价 格：￥电议型 号：T11035产 地：中国大陆
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T11015Midaglizole hydrochloride；咪格列唑盐酸盐(±)-DG5128|||(±)-DG5128 hydrochloride|||DG5128 hydrochloride|||DG
Midaglizole hydrochloride ((±)-DG5128) (DG5128) is a preferred α2-adrenoceptor antagonist. Midazolazole hydrochloride (DG5128) has an affinity for α2-adrenoceptor (pKi = 6.28) 7.4 times higher than that of α1-adrenoceptor.
价 格：￥电议型 号：T11015产 地：中国大陆
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T10958Dapagliflozin-d5；化合物 T10958BMS-512148 D5；BMS-512148 D5
Dapagliflozin D5 (BMS-512148 D5) is deuterated Dapagliflozin. Dapagliflozin is a competitive SGLT2 inhibitor.
价 格：￥电议型 号：T10958产 地：中国大陆
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T10957Dapagliflozin impurity；化合物 T10957Dapagliflozin impurity
Dapagliflozin impurity is the enantiomer of Dapagliflozin, Dapagliflozin is a sodium glucose transporter 2 inhibitor.
价 格：￥电议型 号：T10957产 地：中国大陆
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T10954DAGLβ-IN-1；化合物DAGLβ-IN-1DAGLβ-IN-1
DAGLβ-IN-1 is a universal intermediate for designing DAGL tailored activity-based probes, and is an inhibitor of diacylglycerol lipase-β (DAGLβ).
价 格：￥电议型 号：T10954产 地：中国大陆
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T1095Sparfloxacin；司帕沙星AT-4140|||PD 131501|||Zagam|||CI-978；AT-4140|||PD 131501|||Zagam|||司帕沙星|||CI-978
Sparfloxacin (CI-978) is a fluoroquinolone antibiotic that inhibits bacterial DNA gyrase, thereby inhibiting DNA replication and transcription.
价 格：￥电议型 号：T1095产 地：中国大陆
