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T15117Didesmethyl cariprazine;二去甲基卡利拉嗪Didesmethyl cariprazine
Didesmethyl cariprazine, a metabolite of Cariprazine, is the major cyclic active part. Didesmethyl cariprazine has a long half-life of 1-3 weeks. Cariprazine is a potent D3 preference D3/D2 receptor partial agonist of dopamine for the treatment of schizophrenia, bipolar mania, and depression, with a high affinity for d3 and d2 receptors and a moderate affinity for 5-HT 1A receptors.
价 格:¥电议型 号:T15117产 地:中国大陆
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T15116Dichlorophenyl-ABA;化合物 T15116Dichlorophenyl-ABA
Dichlorophenyl-ABA is a transthyretin (TTR) amyloid fibril formation inhibitor. It inhibits aggregate formation in more than 80% in TTR L55P-expressing cells.
价 格:¥电议型 号:T15116产 地:中国大陆
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T15115Diazo Biotin-PEG3-azide;化合物 T15115Diazo Biotin-PEG3-azide
Diazo Biotin-PEG3-azide, a PEG-based PROTAC linker, is utilized in the synthesis of PROTACs[1].
价 格:¥电议型 号:T15115产 地:中国大陆
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T15114Diazo Biotin-PEG3-alkyne;化合物 T15114Diazo Biotin-PEG3-alkyne
Diazo Biotin-PEG3-alkyne is a polyethylene glycol (PEG)-based linker, specifically designed for the synthesis of proteolysis-targeting chimeras (PROTACs)[1].
价 格:¥电议型 号:T15114产 地:中国大陆
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T15113Diazepinomicin;化合物 T15113TLN-4601|||BU 4664L|||ECO-4601;TLN-4601|||BU 4664L|||ECO-4601
Diazepinomicin is a secondary metabolite produced by Micromonospora sp. It inhibits the EGF-induced Ras-ERK MAPK signaling pathway and induces apoptosis. Diazepinomicin also is an anti-tumor agent for K-Ras mutant models.
价 格:¥电议型 号:T15113产 地:中国大陆
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T15112Dianicline dihydrochloride;化合物 T15112Dianicline dihydrochloride
Dianicline dihydrochloride is a partial agonist of α4β2 nicotinic acetylcholine receptor. It increases cessation rates in a dose-dependent manner.
价 格:¥电议型 号:T15112产 地:中国大陆
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T15111Diacetoxyscirpenol;蛇形菌素,二乙酰镳草镰刀菌烯醇Diacetoxyscirpenol
Diacetoxyscirpenol, a trichothecene mycotoxin, is a secondary metabolite product of fungi. Diacetoxyscirpenol consumption induces hematological disorders in humans and animals.
价 格:¥电议型 号:T15111产 地:中国大陆
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T15110DHQZ 36;化合物 T15110DHQZ 36
DHQZ 36 is a potent retrograde trafficking inhibitor. It has potent anti-parasite activity. DHQZ 36 inhibits Leishmania amazonensis infection in macrophages (EC50: 13.63 μM).
价 格:¥电议型 号:T15110产 地:中国大陆
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T1511Daunorubicin hydrochloride;盐酸柔红霉素Daunomycin HCl|||RP-13057 Hydrochloride|||Rubidomycin hydrochloride
Daunorubicin hydrochloride (Rubidomycin hydrochloride) is an anthracycline aminoglycoside, a topoisomerase II (Topo II) inhibitor. Daunorubicin hydrochloride inhibits DNA and RNA synthesis and has antitumor activity.
价 格:¥电议型 号:T1511产 地:中国大陆
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T15109DGAT1-IN-1;化合物DGAT1-IN-1DGAT1-IN-1
DGAT1-IN-1 is a potent inhibitor of diacylglycerol O- acyltransferase type 1(DGAT1, IC50 of < 10 nM).
价 格:¥电议型 号:T15109产 地:中国大陆
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T15108DG-041;化合物DG-041DG-041
DG-041 is an antagonist of high affinity EP3 receptor (IC50s: 4.6 nM and 8.1 nM in the binding and FLIPR assay, respectively ). DG-041 inhibits PGE2 facilitation of platelet aggregation and it also crosses the blood-brain barrier.
价 格:¥电议型 号:T15108产 地:中国大陆
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T15107DFMTI;化合物 T15107MK5435;MK5435
DFMTI can completely block the rmGlu1 L757V glutamate response.
价 格:¥电议型 号:T15107产 地:中国大陆
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T15106DFHBI;化合物DFHBIDFHBI
DFHBI is a small molecule, resembles the chromophore of green fluorescent protein (GFP). Spinach and DFHBI are essentially nonfluorescent when unbound. The Spinach-DFHBI complex is brightly fluorescent both in vitro and in living cells.
价 格:¥电议型 号:T15106产 地:中国大陆
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T15105Dexloxiglumide;右氯谷胺Dexloxiglumide
Dexloxiglumide, an active enantiomer of Loxiglumide, inhibits smooth muscle cell contractions induced by cholecystokinin-octapeptide (CCK-8). It is a selective antagonist of cholecystokinin type A (CCKA) receptors.
价 格:¥电议型 号:T15105产 地:中国大陆
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T15104Dexetimide;化合物 T15104(+)-Benzetimide|||Dexbenzetimide|||(S)-(+)-Dexetimide;(+)-Benzetimide|||Dexbenz
Dexetimide ((+)-Benzetimide) is a high-affinity antagonist of the muscarinic receptor. It is a persistent anticholinergic agent and can be used to treat neuroleptic-induced parkinsonism.
价 格:¥电议型 号:T15104产 地:中国大陆
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T15102Dexamethasone palmitate地塞米松棕榈酸酯地塞米松棕榈酸酯|||DXP
Dexamethasone palmitate (DXP), a lipophilic prodrug of Dexamethasone, shows a 47-fold lower affinity for the glucocorticoid receptor than Dexamethasone. Dexamethasone palmitate is a glucocorticoid receptor agonist and an anti-inflammatory agent.
价 格:¥电议型 号:T15102产 地:中国大陆
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T15101Devazepide;地伐西匹L-364,718|||MK-329;L-364,718|||地伐西匹|||MK-329
Devazepide is a competitive and orally active nonpeptide antagonist of cholecystokinin (CCK) receptor (IC50s: 81 pM, 45 pM, and 245 nM for rat pancreatic, bovine gallbladder and guinea pig brain CCK receptors, respectively).
价 格:¥电议型 号:T15101产 地:中国大陆
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T15100Desmethyl cariprazine;化合物 T15100Desmethyl cariprazine
Desmethyl cariprazine is a Cariprazine active metabolite. Cariprazine, an antipsychotic drug candidate, shows a high affinity for the D3 (Ki: 0.085 nM) and D2 (Ki: 0.49 nM) receptors, and moderate affinity for the 5-HT1A receptor (2.6 nM).
价 格:¥电议型 号:T15100产 地:中国大陆
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T1510Rosuvastatin calcium;瑞舒伐他汀钙ZD 4522 Calcium|||ZD4522|||Rosuvastatin hemicalcium;ZD 4522 Calcium|||ZD4
Rosuvastatin calcium (ZD4522) , a selective and competitive inhibitor of hepatic hydroxymethyl-glutaryl coenzyme A (HMG-CoA) reductase, has antilipidemic activity.
价 格:¥电议型 号:T1510产 地:中国大陆
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T15081DC_517;化合物 T15081DC_517
DC_517 is an inhibitor of DNA methyltransferase 1 (DNMT1) ( IC50: 1.7 μM; Kd: 0.91 μM).
价 格:¥电议型 号:T15081产 地:中国大陆