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T224972-MPPA;化合物 T224972-MPPA
glutamate carboxypeptidase II (GCP II) inhibitor
价 格:¥电议型 号:T22497产 地:中国大陆
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T224892’-MeCCPA;化合物2’-MeCCPA2-Chloro-N-cyclopentyl-2′-C-methyladenosine;2-Chloro-N-cyclopentyl-2′-C-methyl
2´-MeCCPA is a potent and highly selective A1 adenosine receptor (A1AR) agonist with a K-value of 1.8 nM for AR.2´-MeCCPA inhibits trichostatin-stimulated adenylate cyclase activity with an IC value of 13.1 nM.2´-MeCCPA exhibits analgesic activity and can be used in the study of HCV.
价 格:¥电议型 号:T22489产 地:中国大陆
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T2247KenPaullone;化合物KenPaullone9-Bromopaullone|||NSC-664704;9-Bromopaullone|||NSC-664704|||9-溴-7,12-二氢吲哚并
KenPaullone (9-Bromopaullone), a potent CDK1, CDK2 and CDK5 inhibitor, as new enhancer for iTreg cell differentiation. Kenpaullone promotes iTreg cell differentiation through increased and prolonged transcription of foxp3 gene by enhancing TGFβ-Smad3 signaling pathway.
价 格:¥电议型 号:T2247产 地:中国大陆
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T22412Quinacrine hydrochloride hydrate;米帕林盐酸盐Mepacrine Dihydrochloride Dihydrate|||Quinacrine Dihydrochlor
Quinacrine, a dye of the acridine family, has been widely used as staining agents for DNA and model compounds for intercalators in numerous biophysical studies. It is also an antimalarial drug.
价 格:¥电议型 号:T22412产 地:中国大陆
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T22404Pralidoxime Iodide碘解磷定2-PAM|||碘解磷定
Pralidoxime Iodide, also named 2-PAM, is an antidote approved for reactivation of inhibited acetylcholinesterase (AChE) in organophosphate poisoning.
价 格:¥电议型 号:T22404产 地:中国大陆
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T22395Paroxetine mesylate;甲磺酸帕罗西汀Paroxetine mesylate
Paroxetine Mesylate, the mesylate salt form of paroxetine, is a phenylpiperidine derivative and a selective serotonin reuptake inhibitor (SSRI) with anxiolytic and antidepressant properties.
价 格:¥电议型 号:T22395产 地:中国大陆
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T22393Palonosetron;帕洛诺司琼RS25259|||RS 25259 197;RS25259|||帕洛诺司琼|||RS 25259 197
Palonosetron, a 5-HT3 antagonist with Ki of 0.17 nM, is used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV).
价 格:¥电议型 号:T22393产 地:中国大陆
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T223382,6-Dichloro-N-(2-(cyclopropanecarboxamido)pyridin-4-yl)benzamide;化合物GDC046GDC046;GDC046
2,6-Dichloro-N-(2-(cyclopropanecarboxamido)pyridin-4-yl)benzamide (GDC046), a potent lead analog, has good kinase selectivity, physicochemical properties and pharmacokinetic profile.
价 格:¥电议型 号:T22338产 地:中国大陆
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T22328Ethyl potassium malonate;丙二酸单乙酯钾盐Potassium 3-ethoxy-3-oxopropanoate|||Malonic Acid Monoethyl Ester P
Ethyl potassium malonate, a competitive inhibitor of the enzyme succinate dehydrogenase, acts as a precursor to produce (trimethylsilyl)ethyl malonate, which is utilized to prepare beta-ketoesters by acylation and serves as an intermediate for the preparation of ethyl tert-butyl malonate.
价 格:¥电议型 号:T22328产 地:中国大陆
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T22323Enoxaparin sodium;依诺肝素钠Enoxaparin sodium
Enoxaparin sodium is a low-molecular-weight heparin (LMWH) that has recently been approved by the US FDA for use in patients with medically managed ST-segment myocardial infarction (STEMI), or STEMI with subsequent percutaneous coronary intervention (PCI). It binds to and potentiates the action of antithrombin, and inhibits coagulation factors XIa, IXa, Xa and IIa (thrombin), thereby preventing formation of blood clots.
价 格:¥电议型 号:T22323产 地:中国大陆
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T2230Paeoniflorin;芍药苷Peoniflorin;芍药苷|||Peoniflorin
Paeoniflorin (Peoniflorin) is a herbal constituent extracted from the root of Paeonia albiflora Pall.
价 格:¥电议型 号:T2230产 地:中国大陆
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T22238Alvimopan dihydrate (LY246736 dihydrate);化合物 T22238Alvimopan dihydrate (LY246736 dihydrate)
Alvimopan dihydrate (ADL 8-2698 dihydrate) is a potent, selective, orally active and reversible μ-opioid receptor antagonist, with an IC 50 of 1.7 nM. Alvimopan dihydrate is highly selective for μ-opioid receptor ( Ki =0.47 nM) over κ- and δ-opioid receptors ( Kis =100, 12 nM, respectively). Alvimopan dihydrate can be used for the research of postoperative ileus [1] [2] [3].
价 格:¥电议型 号:T22238产 地:中国大陆
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T22178LSpadin Acetate;化合物Spadin AcetateSpadin Acetate(1270083-24-3 Free base);Spadin Acetate(1270083-24-3 F
Spadin Acetate is a natural peptide derived from a propeptide released in blood. Spadin Acetate is able to block the TREK-1 channel activity. Spadin Acetate binds specifically to TREK-1 with an affinity of 10 nM.
价 格:¥电议型 号:T22178L产 地:中国大陆
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T22135PPIase-Parvulin Inhibitor;化合物PPIase-Parvulin InhibitorPPIase-Parvulin Inhibitor
PPIase-Parvulin Inhibitor is a cell-pemeable inhibitor of the Pin1 and Pin4.
价 格:¥电议型 号:T22135产 地:中国大陆
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T22081FBPase-1 inhibitor-1;化合物T22081Fructose 1,6-bisphosphatase-1 Inhibitor;Fructose 1,6-bisphosphatase-1
FBPase-1 inhibitor-1 (Fructose 1,6-bisphosphatase-1 Inhibitor) is a fructose 1,6-bisphosphatase-1 inhibitor.
价 格:¥电议型 号:T22081产 地:中国大陆
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T21949Calpain Inhibitor XII;化合物 T21949Calpain Inhibitor XII
(Rac)-Calpain Inhibitor XII is a reversible and selective inhibitor targeting calpain I (μ-calpain) with a Ki value of 19 nM. It exhibits lower affinities for calpain II (m-calpain, Ki=120 nM) and cathepsin B (Ki=750 nM). This compound is potentially useful for investigating calpains´ involvement in various processes such as neutrophil chemotaxis, neuronal signaling, and cardiac responses to injury [1].
价 格:¥电议型 号:T21949产 地:中国大陆
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T21907PACOCF3;化合物PACOCF31,1,1-trifluoroheptadecan-2-one|||Palmityltrifluoromet?hylketone;1,1,1-trifluorohe
PACOCF3 (Palmityltrifluoromet?hylketone) (Palmityltrifluoromet hylketone) is an inhibitor of Ca(2+)-independent phospholipase A2(PLA2) with an IC 50 of 3.8 μM. PACOCF3 alters Ca 2+ signaling in renal tubular cells [1] [2].
价 格:¥电议型 号:T21907产 地:中国大陆
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T21871MMPSI;化合物MMPSICaspase-3/7 Inhibitor I;Caspase-3/7 Inhibitor I
MMPSI (Caspase-3/7 Inhibitor I) is a novel, non-peptide small molecule caspase 3 and caspase 7 inhibitor that reduces ischemic injury in isolated rabbit heart or cardiomyocytes and inhibits apoptosis of H16c2 cells in a concentration-dependent manner.MMPSI can be used to study cardioprotection and myocardial injury.
价 格:¥电议型 号:T21871产 地:中国大陆
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T218422-fluoro Palmitic Acid;化合物 T218422-fluoro Palmitic Acid
2-Fluoropalmitic acid, functioning as an acyl-CoA synthetase inhibitor, is a potential anti-glioma agent. It diminishes the viability and stem-like characteristics of glioma stem cells (GSCs) and hinders the proliferation and invasion of glioma cell lines [1].
价 格:¥电议型 号:T21842产 地:中国大陆