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T11320FR194738;化合物FR194738FR194738
FR194738 is an inhibitor of squalene epoxidase with an IC50 of 9.8 nM in HepG2 cell homogenates.
价 格:¥电议型 号:T11320产 地:中国大陆
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T11282LFGTI-2734 mesylate (1247018-19-4 free base);化合物 T11282LFGTI-2734 mesylate;FGTI-2734 mesylate
FGTI-2734 mesylate, a RAS C-terminal mimetic compound with dual farnesyl transferase (FT) and geranylgeranyl transferase-1 (GGT) inhibitory activities (IC50s of 250 nM and 520 nM for FT and GGT, respectively), mitigates KRAS resistance by preventing its membrane localization, effectively impeding mutant KRAS patient-derived pancreatic tumors.
价 格:¥电议型 号:T11282L产 地:中国大陆
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T11247Etravirine D4;依曲韦林 D4R-165335 D4|||TMC-125 D4;R-165335 D4|||TMC-125 D4|||依曲韦林 D4
Etravirine is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used for the treatment of HIV. Etravirine D4 is the deuterium labeled Etravirine.
价 格:¥电议型 号:T11247产 地:中国大陆
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T1124Flumethasone氟米松氟米松|||Flumetasone|||RS-2177|||NSC-54702
Flumethasone (RS-2177) is a glucocorticoid receptor agonist, with anti-inflammatory, antipruritic and vasoconstrictive properties.
价 格:¥电议型 号:T1124产 地:中国大陆
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T11147EC5026;化合物EC5026BPN-19186;BPN-19186
EC5026 (BPN-19186) has the potential to relieve pain by stabilizing natural analgesic and anti-inflammatory mediators.
价 格:¥电议型 号:T11147产 地:中国大陆
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T11143EB-47;化合物EB-47EB-47
EB-47 mimics the substrate NAD+ and extends from the nicotinamide to the adenosine subsite.EB-47, a potent and selective PARP-1/ARTD-1 inhibitor with an IC50 value of 45 nM, shows modest potency against ARTD5 with an IC50 value of 410 nM.
价 格:¥电议型 号:T11143产 地:中国大陆
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T11126Durvalumab;度伐利尤单抗MEDI 4736;MEDI 4736
Durvalumab (MEDI 4736) is a humanized monoclonal antibody targeting PD-L1. It can block the interaction of PD-L1 with PD-1 and CD80, with IC50 values of 0.1 and 0.04 nM, respectively. Durvalumab is often used in combination with platinum-based compounds for the treatment of non-small cell lung cancer and advanced hepatocellular carcinoma cells.
价 格:¥电议型 号:T11126产 地:中国大陆
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T110951Compound F0447-0245;化合物 F0447-0245Compound F0447-0245
Antitubercular agent-33 is a 2-aminothiazole derivative with potent anti-tubercular activity against Mycobacterium tuberculosis ( Mtb ) [1].
价 格:¥电议型 号:T110951产 地:中国大陆
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T11047DiosMetin 7-O-β-D-Glucuronide;化合物DiosMetin 7-O-β-D-GlucuronideDiosMetin 7-O-β-D-Glucuronide
DiosMetin 7-O-β-D-Glucuronide is an antioxidant constituent in the fruits of Luffa cylindrical. The consumption of sponge gourds can supply some antioxidant constituents to the human body.
价 格:¥电议型 号:T11047产 地:中国大陆
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T10988LDegarelix acetate(214766-78-6 free base);化合物Degarelix acetateDegarelix acetate(214766-78-6 free base
Degarelix acetate is a competitive and reversible antagonist of gonadotropin-releasing hormone receptor (GnRHR) .
价 格:¥电议型 号:T10988L产 地:中国大陆
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T1096Milrinone;米力农Win 47203;Win 47203|||米力农
Milrinone (Win 47203) is a Phosphodiesterase 3 Inhibitor. The mechanism of action of milrinone is as a Phosphodiesterase 3 Inhibitor.
价 格:¥电议型 号:T1096产 地:中国大陆
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T10947D8-MMAD;化合物 T10947Monomethylauristatin D D8|||Demethyldolastatin 10 D8|||Monomethyl Dolastatin 10 D8
D8-MMAD is a deuterated form of MMAD, which is a microtubule destroyer.
价 格:¥电议型 号:T10947产 地:中国大陆
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T10883LCRA-026440 hydrochloride;化合物CRA-026440盐酸盐CRA-026440 hydrochloride(847460-34-8 Free base);CRA-026440
CRA-026440 hydrochloride is a potent and broad-spectrum HDAC inhibitor. CRA-026440 hydrochloride exhibits Ki values against recombinant HDAC isoenzymes HDAC1, HDAC2, HDAC3, HDAC6, HDAC8, and HDAC10 are 4 nM, 14 nM, 11 nM, 15 nM, 7 nM, and 20 nM, respectively. CRA-026440 hydrochloride exhibits antitumor and antiangiogenic activities.
价 格:¥电议型 号:T10883L产 地:中国大陆
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T10870LCP-547632;化合物CP-547632CP-547632
CP-547632 is an orally available and potent, ATP-competitive dual inhibitor of VEGFR-2 and FGF kinase F with IC50s of 11 nM and 9 nM, respectively. CP-547632 is selective, with higher selectivity for VEGFR2 and bFGF than for EGFR, PDGFRβ and related tyrosine kinases (TKs). PDGFRβ and related tyrosine kinases (TKs) CP-547632 has antitumour activity.
价 格:¥电议型 号:T10870L产 地:中国大陆
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T10870CP-547632 hydrochloride;化合物 T10870CP-547632 hydrochloride
CP-547632 hydrochloride is a well-tolerated and orally-bioavailable inhibitor of the VEGFR-2 and basic FGF kinases (IC50s: 11 nM and 9 nM) with antitumor efficacy.
价 格:¥电议型 号:T10870产 地:中国大陆
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T10847CMLD012072;化合物 T10847CMLD012072
CMLD012072 is a potent eukaryotic initiation factor 4A (eIF4A) inhibitor with potent anti-neoplastic activity. It can induce RNA clamping of eIF4A1 and eIF4A2.
价 格:¥电议型 号:T10847产 地:中国大陆
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T10747CDK9-IN-9;化合物 T10747CDK9-IN-9
CDK9-IN-9 is a potent and selective CDK9 inhibitor (IC50: 1.8 nM) with anti-cancer activity. It inhibits CDK2 (IC50: 155 nM).
价 格:¥电议型 号:T10747产 地:中国大陆
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T10647c-Fms-IN-8;化合物 T10647c-Fms-IN-8
c-Fms-IN-8 is a colony-stimulating factor-1 receptor (CSF-1R, c-FMS) Type II inhibitor (IC50: 9.1 nM). It is compound 4a in the reference.
价 格:¥电议型 号:T10647产 地:中国大陆
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T10625L(Rac)-IBT6A hydrochloride (1412418-47-3 free base);化合物 T10625L(Rac)-IBT6A hydrochloride;(Rac)-IBT6A
(Rac)-IBT6A hydrochloride is a racemate of IBT6A. IBT6A is an impurity of Ibrutinib. IBT6A can be used in the synthesis of IBT6A Ibrutinib dimer and IBT6A adduct. Ibrutinib is a Btk inhibitor (IC50: 0.5 nM).
价 格:¥电议型 号:T10625L产 地:中国大陆