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T1451LLevofloxacin sodium;化合物 T1451LLevofloxacin sodium
Levofloxacin sodium is a synthetic fluoroquinolones antibacterial. It inhibits the supercoiling activity of bacterial DNA gyrase, so that halting DNA replication.
价 格:¥电议型 号:T1451L产 地:中国大陆
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T14519BDP FL-PEG5-azide;化合物 T14519BDP FL-PEG5-azide
BDP FL-PEG5-azide is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T14519产 地:中国大陆
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T14518BDP FL-PEG4-TCO;化合物 T14518BDP FL-PEG4-TCO
BDP FL-PEG4-TCO is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T14518产 地:中国大陆
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T14517BDP FL-PEG4-amine;化合物 T14517BDP FL-PEG4-amine
BDP FL-PEG4-amine is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T14517产 地:中国大陆
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T14516BDP FL DBCO;化合物 T14516BDP FL DBCO
BDP FL DBCO is a cleavable linker vital in ADC synthesis. BDP FL DBCO joins cytotoxic drugs to antibodies, enabling precise delivery to cells or proteins. The cleavable nature ensures controlled drug release, optimizing ADC effectiveness.
价 格:¥电议型 号:T14516产 地:中国大陆
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T14515BCL6-IN-8c;化合物 T14515BCL6-IN-8c
BCL6-IN-8c is an orally active and potent inhibitor of B-cell lymphoma 6 (BCL6)-corepressor interaction(IC50 of 0.10 μM in cell-free enzyme-linked immunosorbent assay).
价 格:¥电议型 号:T14515产 地:中国大陆
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T14514BCA化合物 T14514Disodium bicinchoninate
BCA is 2,2-Biquinoline-4,4-dicarboxylic acid disodium salt.
价 格:¥电议型 号:T14514产 地:中国大陆
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T14513BBIQ;化合物BBIQBBIQ
BBIQ is a powerful vaccine adjuvant that enhances innate immune responses and a potent and selectively toll-like receptor 7 (TLR7) agonist with an EC50 of ?59.1?nM for human TLR7.
价 格:¥电议型 号:T14513产 地:中国大陆
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T14512BAZ2-ICR;化合物 T14512BAZ2-ICR
BAZ2-ICR is an epigenetic chemical probe and it also is a potent, selective, cell active and orally active BAZ2A/B bromodomains inhibitor with IC50s of 130 nM and 180 nM, and Kds of 109 nM and 170 nM, respectively. BAZ2-ICR shows 10-15-fold selectivity for binding BAZ2A/B over CECR2 and >100-fold selectivity over all other bromodomains.
价 格:¥电议型 号:T14512产 地:中国大陆
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T14511BAY1082439化合物BAY1082439N-[8-[[(2R)-2-羟基-3-(吗啉-4-基)丙基]氧基]-7-甲氧基-2,3-二氢咪唑并[1,2-C]喹唑啉-5-基]-2-甲基吡啶-3-甲酰胺
BAY1082439, an orally bioavailable, selective inhibitor of PI3Kα/β/δ, demonstrates high efficacy in inhibiting the growth of Pten-null prostate cancer [1][2]. Additionally, BAY1082439 is effective against mutated forms of PIK3CA.
价 格:¥电议型 号:T14511产 地:中国大陆
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T14510BAY-850;化合物BAY-850BAY-850
BAY-850 is a selective and potent inhibitor of adenosine triphosphatase family protein 2 (ATAD2) (IC50: 166 nM) that inhibits ovarian cancer growth and metastasis in in vitro and in vivo models.
价 格:¥电议型 号:T14510产 地:中国大陆
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T1451Levofloxacin hydrate;左氧氟沙星半水合物Levaquin hydrate|||Cravit hydrate|||Quixin hydrate|||Levofloxacin Hemi
Levofloxacin hydrate (Cravit hydrate) is a broad-spectrum, third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with antibacterial activity. Levofloxacin diffuses through the bacterial cell wall and acts by inhibiting DNA gyrase (bacterial topoisomerase II), an enzyme required for DNA replication, RNA transcription, and repair of bacterial DNA. Inhibition of DNA gyrase activity leads to blockage of bacterial cell growth.
价 格:¥电议型 号:T1451产 地:中国大陆
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T14451Azido-PEG4-NHS-ester;化合物 T14451Azido-PEG4-NHS-ester
Azido-PEG4-NHS-ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T14451产 地:中国大陆
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T14292Anitrazafen;阿尼扎芬LY 122512;阿尼扎芬|||LY 122512
Anitrazafen is a locally effective anti-inflammatory agent that has been shown to have COX-2 inhibitor activity.
价 格:¥电议型 号:T14292产 地:中国大陆
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T14285AN11251;化合物 T14285AN11251
AN11251, a potent oral-active anti-Wolbachia agent, shows promise for treating onchocerciasis and lymphatic filariasis. Demonstrating EC50 values of 1.5 nM in LDW1 cell lines and 15 nM in C6/36 cell lines, it exhibits significant efficacy across different laboratory settings.
价 格:¥电议型 号:T14285产 地:中国大陆
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T14251Amino-PEG8-Boc;化合物 T14251Amino-PEG8-Boc
Amino-PEG8-Boc is a cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
价 格:¥电议型 号:T14251产 地:中国大陆
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T1425Pemirolast potassium;吡嘧司特钾BMY 26517|||TWT-8152;BMY 26517|||TWT-8152|||吡嘧司特钾
Pemirolast Potassium is the potassium salt form of pemirolast, a pyrimidinone derivative with antiallergic property. Pemirolast potassium (TWT-8152) exerts its action by blocking the antigen-mediated calcium ion influx into mast cells.
价 格:¥电议型 号:T1425产 地:中国大陆
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T14214AMG 511;化合物AMG 511AMG 511
AMG 511 is a potent and orally available pan inhibitor of class I PI3Ks(Kis of 4 nM, 6 nM, 2 nM and 1 nM for PI3Kα, β, δ and γ, respectively). It exhibits anti-tumor activity in mouse glioblastoma xenograft model[1]. AMG 511 significantly suppresses PI3K signaling that is indicated by p-Akt (Ser473) decrease.
价 格:¥电议型 号:T14214产 地:中国大陆
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T14207Amcinafal;安西法尔SQ 15102;安西法尔|||SQ 15102
Amcinafal is an active diol,and used against virus replication and interferon production.
价 格:¥电议型 号:T14207产 地:中国大陆
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T14151AKR1C1-IN-1;化合物AKR1C1-IN-1AKR1C1-IN-1
AKR1C1-IN-1 is a human 20α-hydroxysteroid dehydrogenase (AKR1C1) inhibitor (Ki: 4 nM for AKR1C1).
价 格:¥电议型 号:T14151产 地:中国大陆