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T14144AGN-195183；化合物 T14144AGN-195183
AGN 195183 is a potent and selective agonist of RARα(Kd=3 nM) with improved binding selectivity relative to AGN 193836; no activity on RARβ/γ. IC50 value: 3 nM (Kd); 200 nM (EC80, RAR Trans.) Target: RARα agonist Compound 4(AGN-195183) inhibited the growth of breast cancer cell lines, and was inactive in an in vivo model of topical irritation. Compound 4 (AGN 195183) is currently in Phase I/IIA clinical trials in cancer patients. Compound 4 and ATRA inhibit growth of the human breast cancer cell
价 格：￥电议型 号：T14144产 地：中国大陆
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T14141AGI-24512化合物AGI-24512MAT2A|||S-adenosylmethionine Synthetase|||HCT116
AGI-24512 is a inhibitor of methionine adenosyltransferase 2A (MATA2 ).It is useful for treatment of cancer and blocks growth of MTAP-deleted cancer cells in vitro.
价 格：￥电议型 号：T14141产 地：中国大陆
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T14077A-935142；化合物A-935142A-935142
A-935142 is a human ether-a-go-go-related gene (hERG, Kv 11.1) channel activator. a-935142 enhances hERG currents by slowing inactivation, promoting activation, reducing inactivation, shortening atrial and ventricular repolarization, and in a complex manner.
价 格：￥电议型 号：T14077产 地：中国大陆
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T139851,1,1-Trifluoroethyl-PEG4-alcohol；化合物 T139851,1,1-Trifluoroethyl-PEG4-alcohol
1,1,1-Trifluoroethyl-PEG4-alcohol is a polyethylene glycol (PEG) derivative commonly employed as a linker in the synthesis of protein degrader molecules, known as PROTACs[1].
价 格：￥电议型 号：T13985产 地：中国大陆
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T1398Tadalafil；他达那非Cialis|||IC-351；Cialis|||他达那非|||IC-351|||西力士
Tadalafil (IC-351) is a carboline-based compound with vasodilatory activity. Tadalafil selectively inhibits the cyclic guanosine monophosphate (cGMP)-specific type 5 phosphodiesterase- (PDE-5)-mediated degradation of cGMP, which is found in the smooth muscle of the corpus cavernosa and corpus spongiosum of the penis. Inhibition of cGMP degradation by tadalafil results in prolonged muscle relaxation, vasodilation, and blood engorgement of the corpus cavernosa, and, so, prolonged penile erection.
价 格：￥电议型 号：T1398产 地：中国大陆
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T13951UCB-9260；化合物UCB-9260cytotoxicity|||asymmetric|||trimer|||Inhibitor|||neutrophil|||autoimmune|||UCB92
UCB-9260 inhibits TNF signaling by stabilizing an asymmetric form of the trimer.
价 格：￥电议型 号：T13951产 地：中国大陆
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T13950UC-514321；化合物UC-514321UC-514321
UC-514321 directly targets STAT3/5 and represses TET1 expression. UC-514321 has the potential to treat acute myeloid leukemia (AML) both in vitro and in vivo, with low toxicity.
价 格：￥电议型 号：T13950产 地：中国大陆
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T13851Pseudolaric Acid C2；化合物Pseudolaric Acid C2Pseudolaric Acid C2
Pseudolaric Acid C2 is a diterpenoid isolated from Pseudolarix kaempferi.
价 格：￥电议型 号：T13851产 地：中国大陆
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T13759LTX-401 dihydrochloride (1262851-70-6 free base)；化合物 T13759LTX-401 dihydrochloride；LTX-401 dihydroch
LTX-401, targets the Golgi apparatus, and is an oncolytic amino acid derivative.
价 格：￥电议型 号：T13759产 地：中国大陆
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T13751L-Threonine derivative-1；L-苏氨酸衍生物-1L-Threonine derivative-1
L-Threonine derivative-1 is acetylsalicylic acid-L-threonine ester with potential analgesic activity.
价 格：￥电议型 号：T13751产 地：中国大陆
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T13705GLPG2451；化合物 T13705GLPG2451
GLPG2451 is a cystic fibrosis transmembrane conductance regulator (CFTR) potentiator. It effectively potentiates low temperature rescued F508del CFTR (EC50: 11.1 nM).
价 格：￥电议型 号：T13705产 地：中国大陆
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T13651Diacetazotol双醋佐托Diacetotoluide|||双醋佐托
Diacetazotol (Diacetotoluide) has activity against dioxin-induced ethoxyisochromamide-O-deethylase (EROD,IC50 = 75±4 nM).
价 格：￥电议型 号：T13651产 地：中国大陆
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T13551Araliadiol；化合物 T13551Araliadiol
Araliadiol is a polyacetylenic compound isolated from the leaves of Aralia cordata Thunb. Araliadiol inhibits MCF-7 cell growth (IC50: 6.41 μg/mL).
价 格：￥电议型 号：T13551产 地：中国大陆
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T135196-Aminochrysene；7-胺基去乙酰氧基头胞烷酸6-Chrysenamine；6-Chrysenamine
6-Aminochrysene (6-Chrysenamine) is an inhibitor of the growth of several solid experimental tumors and can be used in studies about splenomegaly, breast cancer and myeloid leukemia.
价 格：￥电议型 号：T13519产 地：中国大陆
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T135185α-Pregnane-3β,6α-diol-20-one；化合物5α-Pregnane-3β,6α-diol-20-one5α-Pregnane-3β,6α-diol-20-one
5α-Pregnane-3β,6α-diol-20-one is a mitogenic metabolite derived from progesterone, capable of being synthesized by androgen-responsive prostate cancer cells under conditions of starvation.
价 格：￥电议型 号：T13518产 地：中国大陆
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T13517Allotetrahydrocortisol；化合物 T135175a-Tetrahydrocortisol；5a-Tetrahydrocortisol
Allotetrahydrocortisol (5a-Tetrahydrocortisol) is a metabolite of Cortisol. Cortisol is the main glucocorticoid in human.
价 格：￥电议型 号：T13517产 地：中国大陆
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T135165-Methyltetrahydrofolic acid；甲基叶酸盐5-Methyl THF；甲基叶酸盐|||5-Methyl THF
5-Methyltetrahydrofolic acid (5-Methyl THF) is a biologically active form of folic acid and a methylated derivate of tetrahydrofolate. It is the predominant natural dietary folate and the principal form of folate in plasma and cerebrospinal fluid.
价 格：￥电议型 号：T13516产 地：中国大陆
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T135155-Methoxytryptophol；5-甲氧基色醇2-(5-Methoxy-1H-indol-3-yl)ethanol|||Methoxytryptophol；2-(5-Methoxy-1H-in
5-Methoxytryptophol (2-(5-Methoxy-1H-indol-3-yl)ethanol) is a pineal indoleamine derived from serotonin shown to be biologically active in a number of species.
价 格：￥电议型 号：T13515产 地：中国大陆
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T135145-MethoxyPinocembroside；5-甲氧基-乔松苷5-MethoxyPinocembroside
5-MethoxyPinocembroside is a flavonoid isolated from leaves of Moringa oleifera.
价 格：￥电议型 号：T13514产 地：中国大陆
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T135135-Methoxyindole-3-acetic acid；5-甲氧基吲哚-3-乙酸Methoxyindoleacetic acid|||5-Methoxyindoleacetic acid；Meth
5-Methoxyindole-3-acetic acid (5-Methoxyindoleacetic acid) is a metabolite of Melatonin and is isolated from pineal tissue.
价 格：￥电议型 号：T13513产 地：中国大陆
