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T22313Dolasetron Mesylate；多拉司琼甲磺酸盐Anzemet hydrate|||MDL-73147EF；多拉司琼甲磺酸盐|||甲磺酸多拉司琼|||Anzemet hydrate|||MDL
Dolasetron Mesylate (MDL-73147EF) is an antagonist of the 5-HT3 receptor and can be used in research on the treatment of vomiting and nausea following chemotherapy.
价 格：￥电议型 号：T22313产 地：中国大陆
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T22280BRITE-338733；化合物BRITE338733BRITE338733；BRITE338733
BRITE-338733 is a novel inhibitor of ATPase. BRITE 338733 inhibits the expression of RecA in bacteria with IC50 value of 4.7 μM for the bacterial infections treatment.
价 格：￥电议型 号：T22280产 地：中国大陆
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T22273BI SF3；化合物BI SF3BI SF3
BI SF3 is an intermediate in the synthesis of heteroarylcarboxamides.
价 格：￥电议型 号：T22273产 地：中国大陆
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T22238Alvimopan dihydrate (LY246736 dihydrate)；化合物 T22238Alvimopan dihydrate (LY246736 dihydrate)
Alvimopan dihydrate (ADL 8-2698 dihydrate) is a potent, selective, orally active and reversible μ-opioid receptor antagonist, with an IC 50 of 1.7 nM. Alvimopan dihydrate is highly selective for μ-opioid receptor ( Ki =0.47 nM) over κ- and δ-opioid receptors ( Kis =100, 12 nM, respectively). Alvimopan dihydrate can be used for the research of postoperative ileus [1] [2] [3].
价 格：￥电议型 号：T22238产 地：中国大陆
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T22194BW 373U86；化合物 T22194BW 373U86
BW373U86 (SNC86), a δ-opioid receptor agonist, demonstrates potent activity with an IC50 value of 1.49 nM and has shown to exhibit antidepressant-like effects [1].
价 格：￥电议型 号：T22194产 地：中国大陆
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T22115SM-7368；化合物NF-κB Activation Inhibitor IIISM-7368
The NF-κB Activation Inhibitor III, controls the biological activity of NF-κB. It is primarily used for Inflammation/Immunology applications.
价 格：￥电议型 号：T22115产 地：中国大陆
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T22106MLS-573151；化合物MLS-573151MLS-573151
MLS-573151 is a selective inhibitor of GTPase Cdc42(EC50 of 2 μM). It is inactive against other GTPases family members, such as Rab2, Rab7, H-Ras, Rac1, Rac 2 and RhoA wild-type. MLS-573151 acts by blocking the binding of GTP to Cdc42.
价 格：￥电议型 号：T22106产 地：中国大陆
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T22087HLI 373；化合物 T22087HLI 373
HLI373 is an efficacious Hdm2 inhibitor. Hdm2 is an ubiquitin ligase (E3). HLI373 is effective in inducing apoptosis of several tumor cells that are sensitive to DNA-damaging agents [1]. HLI 373 also shows prominent antimalarial activity [2].
价 格：￥电议型 号：T22087产 地：中国大陆
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T22018A 987306；化合物 T22018A 987306
A-987306 is a potent and oral bioavailable histamine H 4 antagonist, with Kis of 3.4 nM and 5.8 nM for rat H4, and human H4. A-987306 exhibits anti-inflammatory activity in mice peritonitis model [1].
价 格：￥电议型 号：T22018产 地：中国大陆
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T21996Zoniporide hydrochloride；化合物ZoniporideCP-597396 hydrochloride；CP-597396 hydrochloride
Zoniporide hydrochloride is a selective inhibitor of NHE-1 with IC50 of 14 nM which is >150-fold selectivity versus other NHE isoforms. Zoniporide hydrochloride shows an IC50 of 59 nM for NHE-1-dependent swelling of human platelets.
价 格：￥电议型 号：T21996产 地：中国大陆
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T21864BAY-u 9773；化合物 T21864BAY-u 9773
BAY-u 9773 is a non-selective antagonist of the CysLT receptors (cysteinyl leukotrienes receptors) with about the same IC 50 for CysLT 1 and CysLT 2. BAY-u9773 is used to the inhibit LT responses [1].
价 格：￥电议型 号：T21864产 地：中国大陆
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T21773SP-141；化合物SP 141SP 141；SP 141
SP 141 is a MDM2 inhibitor.SP-141 promotes MDM2 auto-ubiquitination and degradation, with anticancer activity.
价 格：￥电议型 号：T21773产 地：中国大陆
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T21738PF-9184；化合物PF-9184PF-9184
PF-9184 is a potent and selective inhibitor of human microsomal prostaglandin E synthase-1 (mPGES-1), IC50 =16.5 nM. PF-9184 inhibits IL-1β-induced PGE2 synthesis in vitro.
价 格：￥电议型 号：T21738产 地：中国大陆
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T21735NNGH；化合物 T21735NNGH
NNGH functions as an inhibitor of stromelysin-1 (MMP-3), which is not only a direct transcriptional target but also a vital component of the Wnt/β-catenin signaling pathway. Additionally, matrix metalloproteinases (MMPs) are established as playing a crucial role during the later stages of tumor progression [1].
价 格：￥电议型 号：T21735产 地：中国大陆
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T2173Veratridine；藜芦定Veratridine
Veratridine is a benzoate-cevane found in Veratrum and Schoenocaulon. It activates sodium channels to stay open longer than normal.
价 格：￥电议型 号：T2173产 地：中国大陆
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T21673N-Isopropylnoratropine；N-异丙基去甲托品N-Isopropylnoratropine
N-Isopropylnoratropine is a noratropine derivative and an intermediate in the production of ipratropium, an atropine-like bronchodilator drug via an anticholinergic pathway. N-Isopropylnoratropine is used to examine the stability of ipratropium [1].
价 格：￥电议型 号：T21673产 地：中国大陆
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T21473Naftalofos；化合物 T21473Naftalofosum|||Rawetin|||Maretin|||Rametin|||Naphthalophos；Naftalofosum|||Rawet
Naftalofos is an anthelmintic and an insecticide.
价 格：￥电议型 号：T21473产 地：中国大陆
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T21468CVT-2738；N-(2,6-二甲基苯基)-1-哌嗪乙酰胺UNII-NYS3I6283H|||CVT 2738|||EC 610-916-8|||CVT2738|||RS-94287；UNII-NY
CVT-2738 (RS-94287) is a metabolite of Ranolazine. Ranolazine is a partial fatty acid oxidation (pFOX) inhibitor and anti-anginal drug.
价 格：￥电议型 号：T21468产 地：中国大陆
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T21427Mexiletine；化合物 T21427Mexitil|||Mexiletene|||KO-1173|||KO1173|||KO 1173；Mexitil|||Mexiletene|||KO-117
Mexiletine is a non-selective voltage-gated sodium channel blocker. It is a medicine in the class of IB anti-arrhythmic. Mexiletine may also be used in patients experiencing refractory pain and is effective to treat muscle stiffness resulting from myotonic dystrophy or non-dystrophic myotonias.
价 格：￥电议型 号：T21427产 地：中国大陆
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T21410Triptorelin acetate(57773-63-4 free base)；醋酸曲普瑞林Wy 42422|||Triptorelin Acetate|||CL 118532|||AY 2565
Triptorelin acetate(57773-63-4 free base) (CL 118,532) is used as a GnRH agonist. It decreases pituitary secretion of gonadotropins luteinizing hormone (LH) and follicle-stimulating hormone (FSH) by causing constant stimulation of the pituitary. Triptorelin acetate(57773-63-4 free base) may be used in the treatment of hormone-responsive cancers such as breast cancer or prostate cancer, precocious puberty, estrogen-dependent conditions, and assisted reproduction.
价 格：￥电议型 号：T21410产 地：中国大陆
