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T10646c-Fms-IN-7;化合物 T10646c-Fms-IN-7
c-Fms-IN-7 is a cFMS inhibitor (IC50: 18.5 nM).
价 格:¥电议型 号:T10646产 地:中国大陆
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T10586LBPH-1358;化合物BPH-1358NSC50460;NSC50460
BPH-1358 (NSC-50460) (NSC-50460) is a potent human farnesyl diphosphate synthase (FPPS) and undecaprenyl diphosphate synthase (UPPS) inhibitor. With IC50s of 1.8 μM and 110 nM, respectively. And it is active against S. aureus in vitro (MIC ~250 ng/mL)[1][2].
价 格:¥电议型 号:T10586L产 地:中国大陆
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T10586BPH-1358 free base;化合物 T10586NSC50460 free base;NSC50460 free base
BPH-1358 (NSC50460) free base is a potent human undecaprenyl diphosphate synthase (UPPS) and farnesyl diphosphate synthase (FPPS) inhibitor (IC50s: 110 nM and 1.8 μM) and is active against S. aureus in vitro (MIC ~250 ng/mL).
价 格:¥电议型 号:T10586产 地:中国大陆
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T10567BMS-214662;化合物 T10567BMS-214662
BMS-214662 is a potent and selective farnesyl transferase inhibitor that induces mitochondrial apoptosis in primitive CD34+ chronic myeloid leukemia (CML) stem cells/progenitors, and has the ability to selectively target CML stem cells/progenitors with antitumor activity.
价 格:¥电议型 号:T10567产 地:中国大陆
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T10561BM-131246;化合物BM-131246BM-131246
BM-131246 is an orally available and antidiabetic active thiazolidinedione derivative for the study of diabetes.
价 格:¥电议型 号:T10561产 地:中国大陆
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T10546bio-THZ1;化合物 T10546bio-THZ1
bio-THZ1 is a biotinylated version of THZ1. THZ1 is a selective and irreversibly covalent CDK7 inhibitor (IC50: 3.2 nM).
价 格:¥电议型 号:T10546产 地:中国大陆
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T10545BIO-32546;化合物BIO-32546BIO-32546
BIO-32546 (S-isomer) is a highly potent regulator of autotaxin (ATX) with an IC50 value of 1 nM.
价 格:¥电议型 号:T10545产 地:中国大陆
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T10469BAY-298;化合物 T10469BAY-298
BAY-298 is an orally active and selective luteinizing hormone receptor (LH-R) antagonist with IC 50 s of 96 nM, 23 nM and 78 nM for hLH (human LH) and rLH (rat LH) and cLH (cynomolgus monkey LH), respectively. BAY-298 is the first nanomolar hLH-R antagonist reducing sex hormone levels in vivo[1].
价 格:¥电议型 号:T10469产 地:中国大陆
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T10468Elimusertib hydrochloride(1876467-74-1 free base);化合物 Elimusertib hydrochlorideBAY-1895344 hydrochlo
Elimusertib hydrochloride(1876467-74-1 free base) (BAY-1895344 hydrochloride) is a effective, orally available and selective ATR inhibitor with anti-tumor activity.
价 格:¥电议型 号:T10468产 地:中国大陆
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T10467BAY-1816032;化合物BAY-1816032BAY-1816032
BAY-1816032 is a potent and orally available inhibitor of bidding uninhibited by benzimidazoles 1 ( BUB1) kinase (IC50: 7 nM).
价 格:¥电议型 号:T10467产 地:中国大陆
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T10466BAY-1797;化合物BAY-1797BAY-1797
BAY-1797 is an orally active and selective P2X4 antagonist (IC50: 211 nM against human P2X4) with anti-nociceptive and anti-inflammatory effects. BAY-1797 displays no or very weak activity on the other P2X ion channels.
价 格:¥电议型 号:T10466产 地:中国大陆
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T10465Atuveciclib S-Enantiomer;化合物 T10465BAY-1143572 S-Enantiomer;BAY-1143572 S-Enantiomer
Atuveciclib S-Enantiomer (BAY-1143572 S-Enantiomer) is the (S)-enantiomer of BAY-1143572. Atuveciclib S-Enantiomer is a potent and selective CDK9 inhibitor, which inhibits CDK9 / CycT1 with an IC 50 of 16 nM.
价 格:¥电议型 号:T10465产 地:中国大陆
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T10464LAtuveciclib Racemate;阿维西利BAY-1143572 Racemate;BAY-1143572 Racemate|||阿维西利
Atuveciclib Racemate (BAY-1143572 Racemate) is the racemate mixture of Atuveciclib, which is a potent and highly selective, oral P-TEFb/CDK9 inhibitor which supresses CDK9/CycT1 with an IC50 of 13 nM.
价 格:¥电议型 号:T10464L产 地:中国大陆
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T10464Atuveciclib;化合物 T10464BAY-1143572;BAY-1143572
Atuveciclib (BAY-1143572) is a potent and highly selective, oral PTEFb / CDK9 inhibitor that inhibits CDK9 / CycT1 with an IC 50 of 13 nM [1].
价 格:¥电议型 号:T10464产 地:中国大陆
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T10463LBax inhibitor peptide V5 acetate;化合物T10463LBax inhibitor peptide V5 acetate(579492-81-2 free base);B
Bax inhibitor peptide V5 acetate (Bax inhibitor peptide V5 acetate(579492-81-2 free base)) is a Bax-mediated apoptosis inhibitor, used for cancer treatment.
价 格:¥电议型 号:T10463L产 地:中国大陆
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T10463Bax inhibitor peptide V5;化合物 T10463BIP-V5|||BAX Inhibiting Peptide V5;BIP-V5|||BAX Inhibiting Peptid
Bax inhibitor peptide V5 (BIP-V5) is a Bax-mediated apoptosis inhibitor with anticancer activity.
价 格:¥电议型 号:T10463产 地:中国大陆
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T10462LBavisant dihydrochloride hydrate;化合物 T10462LJNJ31001074AAC;JNJ31001074AAC
Bavisant dihydrochloride hydrate (JNJ31001074AAC) is a highly selective, orally active antagonist of the human H3 receptor with a novel mechanism of action, involving wakefulness and cognition, with potential as a treatment for ADHD. in vivo: Mean change from baseline in the total ADHD-RS-IV score at day 42 (primary efficacy endpoint) was -8.8 in the placebo group versus -9.3, -11.2 and -12.2 in the bavisant 1 mg/day, 3 mg/day and 10 mg/day groups, respectively; the change in the 10 mg/day group
价 格:¥电议型 号:T10462L产 地:中国大陆
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T10462Bavisant dihydrochloride;化合物 T10462Bavisant dihydrochloride
Bavisant (JNJ-310010740) dihydrochloride is a highly selective, orally active antagonist of the human H3 receptor with a novel mechanism of action, involving wakefulness and cognition.
价 格:¥电议型 号:T10462产 地:中国大陆
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T10461Batimastat sodium salt;化合物 T10461BB-94 sodium salt;BB-94 sodium salt
Batimastat (BB-94) sodium salt is a broad-spectrum MMP inhibitor (IC50s: 3, 4, 4, 6, and 20 nM for MMP-1, MMP-2, MMP-9, MMP-7, and MMP-3).
价 格:¥电议型 号:T10461产 地:中国大陆
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T10460Batabulin;巴他布林T138067;巴他布林|||T138067
Batabulin (T138067) is an antitumor compound, which binds covalently and selectively to a subset of the β-tubulin isotypes, thereby disrupting microtubule polymerization. Batabulin affects cell morphology and leads to cell-cycle arrest ultimately induce apoptotic cell death.
价 格:¥电议型 号:T10460产 地:中国大陆