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T11095DREADD agonist 21 dihydrochloride；化合物 T11095DREADD agonist 21 dihydrochloride (56296-18-5 free base)
DREADD agonist 21 dihydrochloride is a potent human muscarinic acetylcholine M3 receptors ( hM3Dq ) agonist with EC 50 of 1.7 nM [1].
价 格：￥电议型 号：T11095产 地：中国大陆
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T11073Dofetilide N-oxide；化合物 T11073UK-116856；UK-116856
Dofetilide N-oxide (UK-116856) is a metabolite of dofetilide. Dofetilide can block potassium channels and is a tertiary antiarrhythmic drug.
价 格：￥电议型 号：T11073产 地：中国大陆
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T1107Sarafloxacin hydrochloride；盐酸沙拉沙星Sarafloxacin HCl|||A-56620 (hydrochloride)|||A-56620 HCl；Sarafloxac
Sarafloxacin hydrochloride (A-56620 (hydrochloride)), a quinolone antibiotic drug, is a hydrochloride salt form of sarafloxacin.
价 格：￥电议型 号：T1107产 地：中国大陆
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T11056DLK-IN-1；化合物 T11056DLK-IN-1
DLK-IN-1 is a selective oral active inhibitor of bisleucine zipper kinase (DLK, MAP3K12) with Ki of 3 nM. DLK-IN-1 is active in the Alzheimer´s disease model, retains excellent CNS permeability, and after multiple days of administration, its concentration exceeds the concentration required for DLK inhibition in the brain, so it has good tolerance Acceptability.
价 格：￥电议型 号：T11056产 地：中国大陆
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T10956Dansyl glutathione；化合物 T10956DNS-glutathione；DNS-glutathione
Dansyl glutathione is a capture agent used for quantitative assessment and identification of reactive metabolites.
价 格：￥电议型 号：T10956产 地：中国大陆
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T10856Cobimetinib (R-enantiomer)；考比替尼 (R 型对映体)XL-518 R-enantiomer|||Cobimetinib R-enantiomer|||GDC-0973 R-
Cobimetinib R-enantiomer is the less active R-enantiomer of Cobimetinib which is a selective MEK inhibitor.
价 格：￥电议型 号：T10856产 地：中国大陆
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T10834CL656；化合物 T10834c-[2’FdAMP(S)-2’FdIMP(S)]；c-[2’FdAMP(S)-2’FdIMP(S)]
CL656 is a stimulator of interferon genes (STING) activator.
价 格：￥电议型 号：T10834产 地：中国大陆
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T10756Cenicriviroc Mesylate；化合物 T10756TBR-652 Mesylate|||TAK-652 Mesylate；TBR-652 Mesylate|||TAK-652 Mesyl
Cenicriviroc Mesylate is a dual CCR2/CCR5 antagonist, also inhibits both HIV-1 and HIV-2 with anti-inflammatory and antiinfective activity.
价 格：￥电议型 号：T10756产 地：中国大陆
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T10719CCT365623 hydrochloride；化合物 T10719CCT365623 hydrochloride
CCT365623 hydrochloride is an orally active inhibitor of lysyl oxidase (LOX) (IC50: 0.89 μM). It suppresses EGFR (pY1068) and AKT phosphorylation driven by EGF.
价 格：￥电议型 号：T10719产 地：中国大陆
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T10683Carmoxirole hydrochloride；卡莫昔罗EMD 45609 hydrochloride；EMD 45609 hydrochloride|||卡莫昔罗
Carmoxirole hydrochloride (EMD 45609 hydrochloride) is a selective dopamine D2 receptor agonist with antihypertensive activity in vivo.
价 格：￥电议型 号：T10683产 地：中国大陆
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T10674Potassium Channel Activator 1；钾离子通道激活剂1ZINC34634569；钾离子通道激活剂1|||ZINC34634569
Potassium Channel Activator 1 can be used in studies about the treatment of disorders or conditions wherein the dopaminergic system is disrupted such as mood disorders ADHD, schizophrenia, and other psychotic states.
价 格：￥电议型 号：T10674产 地：中国大陆
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T10656trans-C75；反-4-羧基-5-辛基-3-甲基-丁内酯(±)-C75；(±)-C75|||反-4-羧基-5-辛基-3-甲基-丁内酯
trans-C75 ((±)-C75) is an enantiomer of C75. C75 is an inhibitor of fatty-acid synthase (FASN).
价 格：￥电议型 号：T10656产 地：中国大陆
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T10608BRD5648；化合物BRD5648(R)-BRD0705；(R)-BRD0705
BRD5648 ((R)-BRD0705) is an inactive (R)-enantiomer of BRD0705. BRD0705 is a GSK3α inhibitor (IC50: 66 nM; Kd: 4.8 μM) and can be used in acute myeloid leukemia (AML) studies.
价 格：￥电议型 号：T10608产 地：中国大陆
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T10607BRD5631；化合物 T10607BRD5631
BRD5631 is an autophagy enhancer, enhances autophagy through an mTOR-independent pathway. BRD5631 affects several cellular disease phenotypes previously linked to autophagy, including protein aggregation, cell survival, bacterial replication, and inflammatory cytokine production. BRD5631 can serve as a valuable tool for studying the role of autophagy in the context of cellular homeostasis and disease. [1].
价 格：￥电议型 号：T10607产 地：中国大陆
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T10602BRD 4354 ditrifluoroacetate；化合物 T10602BRD 4354 ditrifluoroacetate (315698-07-8 free base)；BRD 4354 d
BRD 4354 (ditrifluoroacetate) is a moderately potent inhibitor of HDAC5 and HDAC9 (IC50s: 0.85 and 1.88 μM).
价 格：￥电议型 号：T10602产 地：中国大陆
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T10589LBPN-15606；化合物 T10589LBPN-15606
BPN-15606, an orally active γ-secretase modulator (GSM), significantly reduces Aβ42 and Aβ40 production in SHSY5Y neuroblastoma cells, demonstrating IC50 values of 7 nM and 17 nM, respectively. This compound exhibits favorable pharmacokinetic/pharmacodynamic (PK/PD) properties, such as bioavailability, half-life, and clearance. Importantly, BPN-15606 markedly decreases Aβ42 and Aβ40 levels in the central nervous system of both rats and mice[1].
价 格：￥电议型 号：T10589L产 地：中国大陆
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T10589BPN-15606 besylate (1914989-49-3 free base)；化合物 T10589BPN-15606 besylate；BPN-15606 besylate
BPN-15606 besylate is a highly potent, orally active γ-secretase modulator, attenuates the production of Aβ40 and Aβ42 by SHSY5Y neuroblastoma cells (IC50s: 7 nM and 17nM).
价 格：￥电议型 号：T10589产 地：中国大陆
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T10569BMS-654457；化合物 T10569BMS-654457
BMS-654457 is a small-molecule, reversible inhibitor of factor XIa (FXIa; Kis: 0.2 and 0.42 nM for human and rabbit FXIa).
价 格：￥电议型 号：T10569产 地：中国大陆
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T10568BMS-470539 dihydrochloride；化合物 T10568BMS-470539 dihydrochloride
BMS-470539 dihydrochloride is a highly potent and selective agonist of the melanocortin-1 receptor (MC-1R; IC50: 120 nM; EC50: 28 nM) with anti-inflammatory properties. It does not activate MC-3R and is a very weak partial agonist at MC-4R and MC-5R.
价 格：￥电议型 号：T10568产 地：中国大陆
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T10567BMS-214662；化合物 T10567BMS-214662
BMS-214662 is a potent and selective farnesyl transferase inhibitor that induces mitochondrial apoptosis in primitive CD34+ chronic myeloid leukemia (CML) stem cells/progenitors, and has the ability to selectively target CML stem cells/progenitors with antitumor activity.
价 格：￥电议型 号：T10567产 地：中国大陆
