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  • T82950ATIC-IN-1；化合物 ATIC-IN-1ATIC-IN-1

    ATIC-IN-1 (compound 14) serves as an inhibitor specifically aimed at the dimerization of Aminoimidazole carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase (ATIC), with a K i of 685 nM. This dimerization is essential for the enzyme´s aminoimidazole carboxamide ribonucleotide (AICAR) transformylase function. Furthermore, ATIC-IN-1 demonstrates anti-tumor properties by diminishing both cell proliferation and cell division rates [1].

    价 格：￥电议型 号：T82950产 地：中国大陆

  • T82945ATP Synthesis-IN-1；化合物 ATP Synthesis-IN-1ATP Synthesis-IN-1

    ATP Synthesis-IN-1 (Compound 4), a quinoline derivative, potently inhibits PA ATP synthesis with an IC50 of 11.1μg/mL and exhibits antibacterial properties. This compound is utilized in studying drug-resistant PA infections [1].

    价 格：￥电议型 号：T82945产 地：中国大陆

  • T82943AtPCO4-IN-1；化合物 AtPCO4-IN-1AtPCO4-IN-1

    AtPCO4-IN-1 is a selective AtPCO4 inhibitor, exhibiting an IC50 value of 264.4 μM [1].

    价 格：￥电议型 号：T82943产 地：中国大陆

  • T82918BAX-IN-1；化合物 BAX-IN-1BAX-IN-1

    BAX-IN-1 is a potential selective inhibitor of Bcl-2-associated X protein (BAX).

    价 格：￥电议型 号：T82918产 地：中国大陆

  • T82914Bcl-2-IN-12；化合物 Bcl-2-IN-12Bcl-2-IN-12

    Bcl-2-IN-12 (Compound 1) is a potent Bcl-2 inhibitor with an IC50 value of 6 nM, utilized in cancer research [1].

    价 格：￥电议型 号：T82914产 地：中国大陆

  • T82913Bcl-2-IN-13；化合物 Bcl-2-IN-13Bcl-2-IN-13

    Bcl-2-IN-13 is a potent inhibitor of Bcl-2, exhibiting an IC50 of 17 nM, and holds potential for use in cancer research [1].

    价 格：￥电议型 号：T82913产 地：中国大陆

  • T82912Bcl-2-IN-14；化合物 Bcl-2-IN-14Bcl-2-IN-14

    Bcl-2-IN-14 (Compound 13c), a BCL-2 inhibitor, exhibits an inhibitory concentration (IC 50) of 0.471 μM, and is applicable in cancer research [1].

    价 格：￥电议型 号：T82912产 地：中国大陆

  • T82911Bcl-2-IN-15；化合物 Bcl-2-IN-15Bcl-2-IN-15

    Bcl-2-IN-15 (Compound 13d) is a Bcl-2 inhibitor with an IC50 of 363 nM, which impedes the proliferation of the NCI leukemia cancer cell line [1].

    价 格：￥电议型 号：T82911产 地：中国大陆

  • T82910Bcl-2-IN-16；化合物 Bcl-2-IN-16Bcl-2-IN-16

    Bcl-2-IN-16 is a Bcl-2 (B-cell lymphoma 2) inhibitor [1].

    价 格：￥电议型 号：T82910产 地：中国大陆

  • T82765CcpA-IN-1；化合物 CcpA-IN-1CcpA-IN-1

    CcpA-IN-1 is a Staphylococcus aureus antibiotic exhibiting significant bactericidal activity (MICs=460 nM) [1].

    价 格：￥电议型 号：T82765产 地：中国大陆

  • T82758CDK9-Cyclin T1 PPI-IN-1；化合物 CDK9-Cyclin T1 PPI-IN-1CDK9-Cyclin T1 PPI-IN-1

    CDK9-Cyclin T1 PPI-IN-1 (Compound B19) is a selective inhibitor of the CDK9-Cyclin T1 protein-protein interaction (PPI), suppressing cell proliferation in TNBC MDA-MB-231 cells with an IC50 of 0.044 μM and inducing apoptosis. This compound diminishes CDK9 transcriptional activity and downregulates phosphorylation of RNA Pol II CTD ser2. In vivo, CDK9-Cyclin T1 PPI-IN-1 effectively impedes tumor growth in a TNBC 4T1 mouse model [1].

    价 格：￥电议型 号：T82758产 地：中国大陆

  • T82715Cisplatin-resistant cells-IN-1；化合物 Cisplatin-resistant cells-IN-1Cisplatin-resistant cells-IN-1

    Cisplatin-resistant cells-IN-1 (Compound 8) exhibits high cytotoxicity against Cisplatin-resistant cells and effectively diminishes metabolic activity at low nanomolar concentrations, with an IC50 ranging from 0.14 to 1.79 μM in various resistant cell lines, including A549/A549-R, K562/K562-R, and MCF-7/MCF-7TamR [1].

    价 格：￥电议型 号：T82715产 地：中国大陆

  • T82635Cy-FBP/SBPase-IN-1；化合物 Cy-FBP/SBPase-IN-1Cy-FBP/SBPase-IN-1

    Cy-FBP/SBPase-IN-1 (compound S5) serves as an inhibitor of the key regulatory enzyme Cy-FBP/SBPase in cyanobacterial photosynthesis, impeding the Calvin cycle and photosystem, thereby reducing photosynthetic efficiency. It effectively suppresses the proliferation of cyanobacteria, including Synechocystis sp. PCC6803, while demonstrating a safe profile in human-derived cell lines and zebrafish models [1].

    价 格：￥电议型 号：T82635产 地：中国大陆

  • T82614DAM-IN-1；化合物 DAM-IN-1DAM-IN-1

    DMA-IN-1 is a DNA adenine methyltransferase (DAM) inhibitor with an IC50 value of 48 μM. It effectively inhibits Caulobacter growth, exhibiting a minimum inhibitory concentration (MIC) of 35 μM [1].

    价 格：￥电议型 号：T82614产 地：中国大陆

  • T82571DHFR-IN-10；化合物 DHFR-IN-10DHFR-IN-10

    DHFR-IN-10 (compound 4c) is a potent inhibitor of dihydrofolate reductase (DHFR), displaying an inhibition concentration half-maximum (IC50) of 4.21 μM against Mycobacterium tuberculosis DHFR enzyme and demonstrates strong antituberculosis efficacy [1].

    价 格：￥电议型 号：T82571产 地：中国大陆

  • T82570DHFR-IN-11；化合物 DHFR-IN-11DHFR-IN-11

    DHFR-IN-11 (compound 6b) is a DHFR inhibitor with demonstrated inhibitory efficacy against the M. tuberculosis DHFR enzyme, reflected in an IC50 value of 5.70 μM [1].

    价 格：￥电议型 号：T82570产 地：中国大陆

  • T82569DHX9-IN-1；化合物 DHX9-IN-1DHX9-IN-1

    DHX9-IN-1 is a potent ATP-dependent RNA helicase A (DHX9) inhibitor, exhibiting an IC50 of 9.45 nM and demonstrating antitumor activity [1].

    价 格：￥电议型 号：T82569产 地：中国大陆

  • T82483Elastase LasB-IN-1；化合物 Elastase LasB-IN-1Elastase LasB-IN-1

    Elastase LasB-IN-1 (Compound 4b), a potent and selective inhibitor of elastase LasB, exhibits antibacterial activity and has been determined to possess an IC50 value of 76 nM [1].

    价 格：￥电议型 号：T82483产 地：中国大陆

  • T82458Epigenetic factor-IN-1；化合物 Epigenetic factor-IN-1Epigenetic factor-IN-1

    Epigenetic factor-IN-1 (40569Z) is an epigenetic factor inhibitor that exhibits potent binding affinity for SIRT7. It is utilized in the study of liver cancer [1].

    价 格：￥电议型 号：T82458产 地：中国大陆

  • T82421FAAH/cPLA2α-IN-1；化合物 FAAH/cPLA2α-IN-1FAAH/cPLA2α-IN-1

    FAAH/cPLA2α-IN-1 is a compound that simultaneously inhibits both FAAH and cPLA2α, demonstrating potent activity with half-maximal inhibitory concentrations (IC50s) of 32 nM for FAAH and 47 nM for cPLA2α [1].

    价 格：￥电议型 号：T82421产 地：中国大陆

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