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T61684S 17092;化合物 S 17092S 17092
S 17092 (S 17092-1) is a highly effective inhibitor of cerebral prolyl-endopeptidase (PEP), displaying an IC50 value of 1.2 nM. It is utilized in research focused on understanding memory impairment and cognitive disorders associated with cerebral aging [1].
价 格:¥电议型 号:T61684产 地:中国大陆
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T6131Pimasertib;化合物PimasertibAS703026|||MSC1936369B|||SAR 245509;AS703026|||MSC1936369B|||N-[(2S)-2,3-二羟基
Pimasertib (AS703026) is an orally bioavailable small-molecule inhibitor of MEK1 and MEK2 (MEK1/2) with potential antineoplastic activity.
价 格:¥电议型 号:T6131产 地:中国大陆
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T61212Steroid sulfatase-IN-2;化合物 Steroid sulfatase-IN-2Steroid sulfatase-IN-2
Steroid sulfatase-IN-2 is an active inhibitor of steroid sulfatase (STS), demonstrating an IC50 value of 109.5 nM. Its potential application lies in hormone-dependent cancer research, specifically estrogen-dependent breast and endometrial cancer [1].
价 格:¥电议型 号:T61212产 地:中国大陆
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T60929Brassinazole;油菜素唑(2S,3R)-Brassinazole;(2S,3R)-Brassinazole
Brassinazole is a selective inhibitor of triazole-type steroid (BR) biosynthesis.Brassinazole can be used to modulate the oleuropein steroid (BR) signaling pathway, which is used to regulate plant xylem growth and development.
价 格:¥电议型 号:T60929产 地:中国大陆
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T60908SARM1-IN-2;SARM1抑制剂2SARM1-IN-2
SARM1-IN-2 is a potent SARM1 inhibitor for the study of metabolic and neurological related diseases.
价 格:¥电议型 号:T60908产 地:中国大陆
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T60784SSTR4 agonist 2;化合物 SSTR4 agonist 2SSTR4 agonist 2
SSTR4 agonist 2 is a potent somatostatin receptor subtype 4 (SSTR4) agonist that has the potential in SSTR4-related medical disorders research. SSTR4 pathway inhibits the processes of nociceptive and inflammatory [1].
价 格:¥电议型 号:T60784产 地:中国大陆
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T60640SSAO inhibitor-2;化合物 SSAO inhibitor-2SSAO inhibitor-2
SSAO inhibitor-2 (Compound 1) can be used in the research of atherosclerosis, diabetes and its complications, obesity, stroke, chronic kidney disease, retinopathy, chronic obstructive pulmonary disease (COPD), autoimmune diseases, multiple sclerosis, etc. SSAO inhibitor-2 is the inhibitor of semicarbazide-sensitive amine oxidase (SSAO) with IC 50 s <10 nM and 10-100 μM for human SSAO and MAO-A, respectively [1].
价 格:¥电议型 号:T60640产 地:中国大陆
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T6049SNS-032;化合物SNS032SNS032|||BMS-387032;SNS032|||BMS-387032
SNS-032 (BMS-387032) is a selective inhibitor of CDK2 (IC50: 48 nM ) and is 10- and 20-fold selective over CDK1/CDK4. It is also sensitive to CDK7/9 (IC50: 62 nM/4 nM), and no effect on CDK6.
价 格:¥电议型 号:T6049产 地:中国大陆
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T60373SIRT1-IN-2;化合物 SIRT1-IN-2SIRT1-IN-2
SIRT1-IN-2 (compound 3h) is a potent and selective inhibitor of SIRT1 (silent information regulator 1) with an IC 50 of 1.6 μM [1].
价 格:¥电议型 号:T60373产 地:中国大陆
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T60271SARS-CoV-2 nsp3-IN-2;化合物 SARS-CoV-2 nsp3-IN-2SARS-CoV-2 nsp3-IN-2
SARS-CoV-2 nsp3-IN-2 is a SARS-CoV-2 nsp3 macrodomain (Mac1) inhibitor with IC 50 value of 180 μM. SARS-CoV-2 nsp3 macrodomain is an ADP-ribosylhydrolase that is critical for coronavirus replication and pathogenesis. SARS-CoV-2 nsp3-IN-2 is a small molecule chemical probe that can be used for the viral research[1].
价 格:¥电议型 号:T60271产 地:中国大陆
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T60125(2S,3S)-3-Hydroxy-2-methyl-3-phenylpropanoic acid;化合物T60125(2S,3S)-3-Hydroxy-2-methyl-3-phenylpropan
(2S,3S)-3-Hydroxy-2-methyl-3-phenylpropanoic acid is a chemical synthesis intermediate.
价 格:¥电议型 号:T60125产 地:中国大陆
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T5048SSR240612;化合物SSR240612SSR240612
SSR240612 is a potent, and orally active specific non-peptide bradykinin B1 receptor antagonist (Kis = 0.48-0.73 and 358-481 nM for B1 and B2 receptors, respectively).
价 格:¥电议型 号:T5048产 地:中国大陆
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T50068(2S,5S)-3,6-Dioxo-2,5-piperazinediacetamide;化合物 (2S,5S)-3,6-Dioxo-2,5-piperazinediacetamide(2S,5S)-3
2-[(2S,5S)-5-(carbamoylmethyl)-3,6-dioxopiperazin-2-yl]acetamide is a compound used as a molecular structural unit, a cyclic dipeptide. It induces apoptosis, inhibits cell proliferation and modulates immune responses, and possesses a wide range of biological activities including antitumor, antifungal, antibacterial, antiviral and immune-conditioning activities.
价 格:¥电议型 号:T50068产 地:中国大陆
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T4S0999(2S)-Isoxanthohumol;(2S)-异黄腐酚Isoxanthohumol;Isoxanthohumol|||(2S)-异黄腐酚|||异黄腐醇
1. (2S)-Isoxanthohumol shows an antiviral activity towards herpes viruses (HSV1 and HSV2) and bovine viral diarrhea virus (BVDV). 2. Isoxanthohumol is a polyphenol with antioxidant, anti-inflammatory, and antiangiogenic properties, seems to regulate in vivo vascular proliferation and stabilization and the EC-VSMC-inflammatory crosstalk.
价 格:¥电议型 号:T4S0999产 地:中国大陆
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T4866H-Trp-NH2.HCl;L-色氨酰胺盐酸盐L-Tryptophanamide hydrochloride|||(2S)-2-amino-3-(1H-indol-3-yl)propanamide h
H-Trp-NH2.HCl ((2S)-2-amino-3-(1H-indol-3-yl)propanamide hydrochloride) is an endogenous metabolite that has been detected in various biological fluids, e.g. Urine and blood.
价 格:¥电议型 号:T4866产 地:中国大陆
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T4856Acetyl-L-lysine;N-乙酰-L-赖氨酸Nα-Acetyl-L-lysine|||(2S)-2-Acetamido-6-aminohexanoic acid;N-乙酰-L-赖氨酸|||Nα
Acetyl-L-lysine (Nα-Acetyl-L-lysine) is a N-acetylated amino acid. It is a normal constituent of human urine with concentrations in normal samples too small to allow its routine detection; however, it has been found at increased levels in the urine of a patient with aminoacylase I deficiency.
价 格:¥电议型 号:T4856产 地:中国大陆
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T4709(2S,3R,4S,5R)-2-Amino-3,4,5,6-tetrahydroxyhexanal hydrochloride;盐酸 D-甘露糖胺D-Mannosamine hydrochloride
(2S,3R,4S,5R)-2-Amino-3,4,5,6-tetrahydroxyhexanal hydrochloride (D-Mannosamine hydrochloride) is a pharmaceutical compound used in the development of mannosylated liposomes for bioadhesive oral drug delivery via M cells of Peyer´s patches.
价 格:¥电议型 号:T4709产 地:中国大陆
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T4662SJ000291942;化合物SJ000291942SJ000291942
SJ000291942 is an activator of the canonical bone morphogenetic proteins (BMP) signaling pathway.
价 格:¥电议型 号:T4662产 地:中国大陆
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T4460Dapagliflozin ((2S)-1,2-propanediol, hydrate);达格列净 (2S)-1,2-丙二醇水合物BMS-512148 (2S)-1,2-propanediol, h
Dapagliflozin ((2S)-1,2-propanediol, hydrate) (BMS-512148 (2S)-1,2-propanediol, hydrate) is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2). It is in development for the treatment of type 2 diabetes mellitus (T2DM). It inhibits subtype 2 of the sodium-glucose transport proteins (SGLT2), which is responsible for at least 90% of the glucose reabsorption in the kidney.
价 格:¥电议型 号:T4460产 地:中国大陆
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T4353SR-18292;化合物SR18292SR 18292;SR 18292
SR-18292 is an inhibitor of PPAR gamma coactivator-1α (PGC-1α), which increases PGC-1α acetylation, suppresses gluconeogenic gene expression and reduces glucose production in hepatocytes.
价 格:¥电议型 号:T4353产 地:中国大陆