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T19297Doxazosin D8;化合物 T19297UK 33274 D8;UK 33274 D8
Doxazosin D8 (UK 33274 D8) is a deuterium labeled Doxazosin (UK 33274).Doxazosin, a quinazoline derivative, selectively antagonizes postsynaptic AP1 adrenergic receptor.
价 格:¥电议型 号:T19297产 地:中国大陆
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T1835Ibrutinib;伊布替尼PCI-32765;伊布替尼|||依鲁替尼|||PCI-32765
Ibrutinib (PCI-32765) is a Bruton´s tyrosine kinase (BTK) inhibitor (IC50=0.5 nM) with irreversible and selective properties. Ibrutinib blocks BTK to inhibit the proliferation and survival of B cells, and possesses antitumor activity, which can be used for the treatment of chronic lymphocytic leukemia, among others.
价 格:¥电议型 号:T1835产 地:中国大陆
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T18327MC-Val-Cit-PAB-Retapamulin;化合物 T18327MC-Val-Cit-PAB-Retapamulin
MC-Val-Cit-PAB-Retapamulin is a drug-linker conjugate for antibody-drug conjugates (ADC) that exhibits potent antitumor activity. This compound utilizes Retapamulin, a ribosome inhibitor, connected through the ADC linker MC-Val-Cit-PAB.
价 格:¥电议型 号:T18327产 地:中国大陆
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T173272-(Azido-PEG3-amido)-1,3-bis(NHS ester);化合物 T173272-(Azido-PEG3-amido)-1,3-bis(NHS ester)
2-(Azido-PEG3-amido)-1,3-bis(NHS ester) is a polyethylene glycol (PEG)-based linker for PROTAC synthesis [1].
价 格:¥电议型 号:T17327产 地:中国大陆
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T17243VU0463271;化合物VU0463271N-Cyclopropyl-N-(4-methyl-2-thiazolyl)-2-[(6-phenyl-3-pyridazinyl)thio]acetami
VU0463271 (N-Cyclopropyl-N-(4-methyl-2-thiazolyl)-2-[(6-phenyl-3-pyridazinyl)thio]acetamide) is a potent and selective antagonist of the neuronal-specific potassium-chloride cotransporter 2 (KCC2), with an IC50 of 61 nM and >100-fold selectivity versus the closely related Na-K-2Cl cotransporter 1 (NKCC1) and no activity in a larger panel of GPCRs, ion channels, and transporters.
价 格:¥电议型 号:T17243产 地:中国大陆
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T16488PF-06263276;化合物 T16488PF-06263276
PF-06263276 is an effective and selective inhibitor of pan-JAK. It also has IC50s of 2.2 nM, 23.1 nM, 59.9 nM and 29.7 nM for JAK1, JAK2, JAK3, and TYK2, respectively.
价 格:¥电议型 号:T16488产 地:中国大陆
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T16440Ibrutinib Racemate化合物 T16440PCI-32765 (Racemate)
Ibrutinib is a selective, irreversible Btk inhibitor (IC50: 0.5 nM). Ibrutinib Racemate is the racemate of Ibrutinib.
价 格:¥电议型 号:T16440产 地:中国大陆
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T16327Nitracrine;二胺硝吖啶Nitracrine
Nitracrine is a 1-nitroacridine derivative and is an effective hypoxia-selective agent in vitro and antitumor drugs. Nitracrine suppresses RNA synthesis and covalently, reversibly binds to DNA but also forms covalent adducts with DNA in vivo. Nitracrine has cytotoxicity towards most cells.
价 格:¥电议型 号:T16327产 地:中国大陆
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T15340Fosdagrocorat;化合物 T15340PF-04171327;PF-04171327
Fosdagrocorat is an agonist of the dissociated glucocorticoid receptor.
价 格:¥电议型 号:T15340产 地:中国大陆
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T15327Fmoc-PEG1-CH2CH2-NHS ester;化合物 T15327Fmoc-PEG1-CH2CH2-NHS ester
Fmoc-PEG1-CH2CH2-NHS ester is a polyethylene glycol (PEG) derived linker specifically designed for the synthesis of proteolysis-targeting chimeras (PROTACs)[1].
价 格:¥电议型 号:T15327产 地:中国大陆
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T14864Caracemide;卡醋胺NSC-253272;NSC-253272|||卡醋胺
Caracemide (NSC-253272) inhibits the enzyme ribonucleotide reductase of Escherichia coli. Caracemide can be used in anticancer studies.
价 格:¥电议型 号:T14864产 地:中国大陆
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T14327AS1949490;化合物AS1949490AS1949490
AS1949490 activated glucose metabolism via up-regulation of GLUT1 gene in L6 myotubes[1][2]. AS1949490 is a potent and selective SHIP-2 (SH2 domain-containing inositol 5′ phosphatase 2) inhibitor, with an IC50 of 620 nM.
价 格:¥电议型 号:T14327产 地:中国大陆
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T140555Z-7-Oxozeaenol;化合物5Z-7-OxozeaenolFR148083|||L783279|||LL-Z 1640-2;FR148083|||L783279|||LL-Z 1640-2
5Z-7-Oxozeaenol (FR148083) is a potent, irreversible and selective inhibitor of transforming growth factor (TGF)-β-activated kinase 1 with IC50 of 8.1 nM for TAK1 and low activity against MEK1 with IC50 of 411 nM, it is also an inhibitor of VEGF-R2 with IC50 of 52 nM.
价 格:¥电议型 号:T14055产 地:中国大陆
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T13327W146;化合物 T13327W 146|||W-146;W 146|||W-146
W146 is a selective sphingosine-1-phosphate receptor 1 (S1PR1) antagonist (EC50: 398 nM).
价 格:¥电议型 号:T13327产 地:中国大陆
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T13279LValemetostat;化合物ValemetostatDS-3201;DS-3201
Valemetostat (DS-3201) is a first-in-class EZH1/2 dual inhibitor.
价 格:¥电议型 号:T13279L产 地:中国大陆
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T13279Valemetostat tosylate化合物 T13279DS-3201 tosylate
Valemetostat tosylate is a dual inhibitor of EZH1/2 and used in the research of relapsed/refractory peripheral T-cell lymphoma.
价 格:¥电议型 号:T13279产 地:中国大陆
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T13278LValecobulin;化合物 T13278LCKD-516;CKD-516
Valecobulin is a potent β-tubulin polymerization inhibitor. Valecobulin is a valine prodrug of (S516) and an avascular disrupting compound.
价 格:¥电议型 号:T13278L产 地:中国大陆
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T13278Valecobulin hydrochloride;化合物Valecobulin hydrochlorideCKD-516 hydrochloride;CKD-516 hydrochloride
Valecobulin hydrochloride (CKD-516 hydrochloride) is a potent inhibitor of β-tubulin polymerization. Valecobulin hydrochloride is a valine prodrug and a vascular disrupting agent.
价 格:¥电议型 号:T13278产 地:中国大陆
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T13277Valategrast;化合物 T13277R-411 free base;R-411 free base
Valategrast is a potent and orally active dual antagonist of integrin α4β1 (VLA-4) and α4β7, with the potential for Chronic obstructive pulmonary disease (COPD) and asthma treatment.
价 格:¥电议型 号:T13277产 地:中国大陆
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T13276VAF3474-(3-氯苯基)-N-[4-(三氟甲基)苯基]嘧啶-2-胺4-(3-氯苯基)-N-[4-(三氟甲基)苯基]嘧啶-2-胺
VAF347 is a cell-permeable and highly affinity agonist of the aryl hydrocarbon receptor (AhR) with anti-inflammatory effects.
价 格:¥电议型 号:T13276产 地:中国大陆