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产品数:86101
参观次数:3716173
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T6274RO4929097RG-4733
RO4929097, a γ secretase inhibitor (IC50: 4 nM), inhibits cellular processing of Aβ40 and Notch (EC50: 14/5 nM).
价 格:¥电议型 号:T6274产 地:中国大陆
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T6273Vadimezan伐地美生;ASA-404;NSC 640488;5,6-Dimethylxanthenone-4-acetic Acid;DMXAA
Vadimezan is a fused tricyclic analogue of flavone acetic acid with potential antineoplastic activity. Vadimezan induces the cytokines tumor necrosis alpha (TNF-alpha), serotonin and nitric oxide, resulting in hemorrhagic necrosis and a decrease in angiog
价 格:¥电议型 号:T6273产 地:中国大陆
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T6267Lomitapide洛美他派;AEGR-733;BMS-201038
Lomitapide is a small molecule inhibitor of microsomal triglyceride transfer protein (MTP), an enzyme located in the lumen of the endoplasmic reticulum responsible for absorbing dietary lipids and transferring triglycerides onto apolipoprotein B (apo-B) i
价 格:¥电议型 号:T6267产 地:中国大陆
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T6254IdasanutlinRo 5503781;RG7388;依达奴林
Idasanutlin (RG-7388) is an effective and specific p53-MDM2 inhibitor (IC50: 6 nM).
价 格:¥电议型 号:T6254产 地:中国大陆
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T6253Talazoparib他拉唑帕利;BMN-673;LT-673
Talazoparib is a new-type PARP inhibitor (IC50: 0.58 nM), It similarly binds to PARP1/2 (Kis: 1.2/0.85 nM).
价 格:¥电议型 号:T6253产 地:中国大陆
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T6243U-73122U73122
U73122, an effective PLC inhibitor, reduces agonist-induced Ca2+ increases in platelets and PMN.
价 格:¥电议型 号:T6243产 地:中国大陆
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T6202DAPTGSI-IX;LY-374973
DAPT is a novel γ-secretase inhibitor which reduces the Aβ production (IC50: 20 nM in HEK 293 cells) and Aβ42 levels (IC50: 200 nM).
价 格:¥电议型 号:T6202产 地:中国大陆
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T6191Tasisulam他司磺胺;LY573636
Tasisulam is an apoptosis inducer and an antitumor agent via the intrinsic pathway.
价 格:¥电议型 号:T6191产 地:中国大陆
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T6173BI 25364-[[(7R)-8-环戊基-7-乙基-5,6,7,8-四氢-5-甲基-6-氧代-2-喋啶基]氨基]-3-甲氧基-N-(1-甲基-4-哌啶基)苯甲酰胺
BI2536 is an effective Plk1 inhibitor (IC50: 0.83 nM). It has 4- and 11-fold greater selectivity than Plk2 and Plk3.
价 格:¥电议型 号:T6173产 地:中国大陆
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T6139LA-674563 2HCl(552325-73-2(fb-2hcl))
A-674563 is an Akt1 inhibitor with Ki of 11 nM, modest potent to PKA and >30-fold selective for Akt1 over PKC.
价 格:¥电议型 号:T6139L产 地:中国大陆
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T6127Rucaparib Phosphate芦卡帕利;瑞卡帕布磷酸盐;PF-01367338 phosphate;AG-014699;AG-014699 phosphate;PF-01367338
Rucaparib is an inhibitor of PARP (Ki: 1.4 nM for PARP1) that is used in clinical therapy to sensitize cancer cells to chemotherapy.
价 格:¥电议型 号:T6127产 地:中国大陆
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T6101EntospletinibGS-9973
Entospletinib (IC50= 7.7 nM)is a specific Syk inhibitor, which is orally bioavailable.
价 格:¥电议型 号:T6101产 地:中国大陆
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T6091CP-673451CP 673451;CP673451
CP-673451 is a specific inhibitor of PDGFRα/β (IC50: 10/1 nM) with antiangiogenic and antitumor activity and the selectivity is higher 450-fold than other angiogenic receptors.
价 格:¥电议型 号:T6091产 地:中国大陆
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T6073OG-L002
OG-L002 is an effective and selective LSD1 inhibitor (IC50: 20 nM), showing 69- and 36-fold selectivity over MAO-A and MAO-B, respectively.
价 格:¥电议型 号:T6073产 地:中国大陆
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T6048DalcetrapibJTT-705;RO4607381;达塞曲匹
Dalcetrapib, a rhCETP inhibitor (IC50=0.2 μM), increases the plasma HDL cholesterol.
价 格:¥电议型 号:T6048产 地:中国大陆
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T6028PF 477736PF477736;PF 00477736;PF-477736;PF-736,PF-00477736
PF-477736 is a specifc, effective and ATP-competitive Chk1 inhibitor (Ki: 0.49 nM ) and also inhibits FGFR3, Aurora-A, VEGFR2, Flt3, Fms (CSF1R), Ret and Yes.
价 格:¥电议型 号:T6028产 地:中国大陆
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T60004SRI-37330
SRI-37330 inhibits glucagon secretion and function, reduces hepatic glucose production, and reverses hepatic steatosis.
价 格:¥电议型 号:T60004产 地:中国大陆
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T5S0734Desmethoxyyangonin去甲氧基醉椒素;Demethoxyyangonin;Desmethoxy yangonin;5,6-Dehydrokavain
1. Desmethoxy yangonin protects LPS or LPS/D-GalN-induced damages in cell or liver tissues mainly through de-regulating IKK/NFκB and Jak2/STAT3 signaling pathways. 2. The induction of CYP3A23 by dihydromethysticin and Desmethoxy yangonin involves transcri
价 格:¥电议型 号:T5S0734产 地:中国大陆
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T5S0733Picroside III
Picroside III, an iridoid glucoside found in the root of Picrorhiza scrophulariiflora Pennell (Scrophulariaceae), and its subtype Picroside II has been demonstrated to reduce apoptosis in neuronal cells and other cell types.
价 格:¥电议型 号:T5S0733产 地:中国大陆
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T5S0273Hypaphorine刺桐碱;Tryptophan Betaine;Glyyunnanenine;Lenticin
1. Hypaphorine is an indole-3-acetic acid antagonist which specifically compete with indole-3-acetic acid in binding to the indole-3-acetic acid-binding site in plant peroxidases.
价 格:¥电议型 号:T5S0273产 地:中国大陆