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产品数:86101
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TN2244Sulfuretininflammation,platelet,Allergic,Sulfuretin,Nuclear factor-kappaB,Airway,Inhibitor,aggregati
Sulfuretin is a potent anti-oxidant, has protective effect against t-BHP-induced oxidative damage in human liver-derived HepG2 cells is attributable to its ability to scavenge ROS and up-regulate the activity of HO-1 through the Nrf2/ARE and JNK/ERK signaling pathways.
价 格:¥电议型 号:TN2244产 地:中国大陆
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T6750Opaganibinhibit,SphK,Opaganib,Sphingosine kinase,ABC-294640,Inhibitor,ABC 294640
ABC294640 is an orally active and specific sphingosine kinase-2 (SphK2) inhibitor (IC50: 60 μM).
价 格:¥电议型 号:T6750产 地:中国大陆
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T7217BexagliflozinBexagliflozin
EGT1442 is a potent, selective sodium glucose co-transporter 2 (SGLT2) inhibitor with IC50 values of 5.6 μM and 2 nM for human SGLT1 and SGLT2, respectively
价 格:¥电议型 号:T7217产 地:中国大陆
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T6580MeprednisoneMeprednisone,Autophagy,Glucocorticoid Receptor,Inhibitor,inhibit
Betapar(Meprednisone) is a glucocorticoid and a methylated derivative of prednisone.
价 格:¥电议型 号:T6580产 地:中国大陆
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TQ0180Chebulagic acidSARS coronavirus,LOX,Cyclooxygenase,inhibit,Chebulagic acid,Inhibitor,Lipoxygenase,CO
Chebulagic acid, isolated from the Terminalia chebula Retz, is a COX-LOX dual inhibitor.
价 格:¥电议型 号:TQ0180产 地:中国大陆
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T6134IEM 1754 2HBrAMPA receptor,channel block,IEM 1754,Ionotropic glutamate receptors,voltage dependence,
IEM 1754 2HBr is a selective AMPA/kainate receptor blockers for GluR1 and GluR3 with IC50 of 6 μM.
价 格:¥电议型 号:T6134产 地:中国大陆
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T6731WYE-354inhibit,Apoptosis,WYE354,WYE-354,WYE 354,Inhibitor,Autophagy,Mammalian target of Rapamycin,mT
WYE-354(IC50=5 nM) is an effective, selective and ATP-competitive mTOR inhibitor. It blocks mTORC2/P-AKT(S473) and mTORC1/P-S6K(T389), not P-AKT(T308). The selectivity for mTOR is higher than PI3Kα (>100-fold) and PI3Kγ (>500-fold).
价 格:¥电议型 号:T6731产 地:中国大陆
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TN1677GartaninFungal,Autophagy,Gartanin,inhibit,Inhibitor
Gartanin is an androgen receptor degradation enhancer, it is also a potential neuroprotective agent against glutamate-induced oxidative injury partially through increasing Nrf-2-independed HO-1 and AMPK/SIRT1/PGC-1α±signaling pathways.
价 格:¥电议型 号:TN1677产 地:中国大陆
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T6576Malotilateinjury,LOX,NKK-105,Inhibitor,collagen,oral,migration,Malotilate,inhibit,hepatotropic,anti-
Malotilate is a medicine used for the therapy of liver cirrhosis.
价 格:¥电议型 号:T6576产 地:中国大陆
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T27471GSK299115AGSK299115A
GSK299115A is a selective ROCK1 Inhibitor. GSK299115A exhibits IC50 of 8nM, 620nM, 560nM for ROCK1, RSK1, p70S6K, respectively.
价 格:¥电议型 号:T27471产 地:中国大陆
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T60523Agomelatine hydrochloride
Agomelatine hydrochloride (S-20098 hydrochloride) is a specific MT1 and MT2 receptor agonist with Ki of 0.1 nM for CHO-hMT1, 0.06 nM for HEK-hMT1, 0.12 nM for CHO-hMT2, and 0.27 nM for HEK-hMT2, respectively [1]. Agomelatine hydrochloride is a selective antagonist of a 5-HT2C receptor with pKis of 6.4 and 6.2 for native (porcine) and cloned, human 5-HT2C receptors, respectively [2].
价 格:¥电议型 号:T60523产 地:中国大陆
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T10031EP1-antagonist-1
EP1-antagonist-1 is an EP1 antagonist (pKi: 7.54; pIC50: 8.5).
价 格:¥电议型 号:T10031产 地:中国大陆
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T7823IDRA-21IDRA-21,memory,Inhibitor,inhibit,orally active,Ionotropic glutamate receptors,IDRA 21,aging,e
IDRA-21 is a positive AMPA receptor modulator.
价 格:¥电议型 号:T7823产 地:中国大陆
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TQ0223LusutrombopagLusutrombopag,inhibit,Inhibitor,S888711,S 888711,Thrombopoietin Receptor
Lusutrombopag is an orally bioavailable, small molecule thrombopoietin (TPO) receptor agonist for chronic liver disease (CLD) patients with thrombocytopenia prior to elective invasive surgery.
价 格:¥电议型 号:TQ0223产 地:中国大陆
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TL0004FERULIC ACID METHYL ESTERInhibitor,inhibit,p38 MAPK,Autophagy,FERULIC ACID METHYL ESTER
Ferulic acid is a hydroxycinnamic acid that is abundant in plants and originally derived from giant fennel (F. communis). This naturally-occurring phenolic has antioxidant activities that provide protection against inflammation and cancer. Ferulic acid methyl ester is a lipophilic derivative of ferulic acid, demonstrating increased ability to cross cell membranes.
价 格:¥电议型 号:TL0004产 地:中国大陆
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T9966GSK-1520489AGSK1520489A,inhibit,GSK 1520489A,HT29,GSK-1520489A,Inhibitor,active protein kinase
GSK-1520489A is an active PKMYT1 inhibitor.
价 格:¥电议型 号:T9966产 地:中国大陆
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T6474Divalproex SodiumMitophagy,Notch,Apoptosis,Histone deacetylases,Autophagy,hepatic fat accumulation,H
Divalproex Sodium binds to and inhibits gamma-aminobutyric acid (GABA) transaminase and its anticonvulsant activity may be exerted by increasing brain concentration of GABA and by inhibiting enzymes that catabolize GABA or block the reuptake of GABA into glia and nerve endings. It also is an HDAC inhibitor. Divalproex Sodium is a stable coordination compound comprised of sodium valproate and valproic acid with anticonvulsant and antiepileptic activities. Divalproex may also work by suppressing r
价 格:¥电议型 号:T6474产 地:中国大陆
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T6863Isosorbide MononitrateAutophagy,inhibit,Isosorbide Mononitrate,Inhibitor
Isosorbide mononitrate is a Nitrate Vasodilator, dilating the blood vessels so as to reduce the blood pressure.
价 格:¥电议型 号:T6863产 地:中国大陆
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T8641VancomycinInhibitor,Vancomycin,Antibiotic,inhibit,Autophagy,Bacterial
Vancomycin is an antibiotic used to treat serious bacterial infections by stopping the growth of bacteria.
价 格:¥电议型 号:T8641产 地:中国大陆
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T6696Tazaroteneinhibit,Inhibitor,Tazarotene,AGN-190168,RAR/RXR,AGN190168,Retinoic acid receptors,Autophag
Tazarotene is a synthetic, topical retinoid. Tazarotene induces the expression of tazarotene-induced gene 3 (TIG3), a tumor suppressor gene. In psoriasis, tazarotene normalizes abnormal keratinocyte differentiation and reduces their hyperproliferation.
价 格:¥电议型 号:T6696产 地:中国大陆