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T38590Biotin-PEG1-azide；Biotin-PEG1-azideBiotin-PEG1-azide；Biotin-PEG1-azide
Biotin-PEG1-azide is a cleavable 1-unit polyethylene glycol (PEG) linker employed in the synthesis of antibody-drug conjugates (ADCs).
价 格：￥电议型 号：T38590产 地：中国大陆
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T38576Propargyl-PEG1-THP；Propargyl-PEG1-THPPropargyl-PEG1-THP；Propargyl-PEG1-THP
Propargyl-PEG1-THP is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T38576产 地：中国大陆
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T38503(2-pyridyldithio)-PEG1-hydrazine；(2-pyridyldithio)-PEG1-hydrazine(2-pyridyldithio)-PEG1-hydrazine；(2
(2-Pyridyldithio)-PEG1-hydrazine is a one-unit cleavable polyethylene glycol (PEG) linker specifically designed for the synthesis of antibody-drug conjugates (ADCs). This linker offers the advantage of controlled release of the drug payload from the ADC construct. It is utilized in the conjugation process between the antibody and the cytotoxic drug, enabling the targeted delivery of the drug to cancer cells. The (2-pyridyldithio) group of this linker provides stability during circulation in the
价 格：￥电议型 号：T38503产 地：中国大陆
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T38498Azido-PEG12-alcohol；Azido-PEG12-alcoholAzido-PEG12-alcohol；Azido-PEG12-alcohol
Azido-PEG12-alcohol is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T38498产 地：中国大陆
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T38162STING18；STING18STING18
STING18 is a competitive ligand of stimulator of interferon genes (STING; IC50 = 0.068 μM in a radioligand binding assay).1 It inhibits cGAMP-induced IFN-β production (IC50 = 11 μM) but does not stimulate IFN-β production (EC50 = >30 μM) in THP-1 cells.
价 格：￥电议型 号：T38162产 地：中国大陆
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T3725K-Ras(G12C) Inhibitor 6；化合物K-Ras(G12C) Inhibitor 6K-Ras(G12C) Inhibitor 6
K-Ras(G12C) inhibitor 6 is an irreversible, allosteric inhibitor of the K-Ras(G12C) mutant that causes 100% modification of the protein when used at 10 μM for 24 hours in vitro.
价 格：￥电议型 号：T3725产 地：中国大陆
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T36711FM19G11；化合物FM19G11FM19G11|||HIF-1alpha/2alpha Inhibitor；FM19G11|||HIF-1alpha/2alpha Inhibitor
FM19G11 is an inhibitor of hypoxia inducible factor (HIF) α-subunit (IC50 = 80 nM in hypoxia induced luciferase assay).
价 格：￥电议型 号：T36711产 地：中国大陆
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T36285VH 032 amide-PEG1-acid；VH 032 amide-PEG1-acidVH 032 amide-PEG1-acid；VH 032 amide-PEG1-acid
Functionalized von-Hippel-Lindau (VHL) protein ligand for PROTAC research and development; incorporates an E3 ligase ligand plus a PEG1 linker with terminal carboxylic acid ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.
价 格：￥电议型 号：T36285产 地：中国大陆
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T36264(S,R,S)-AHPC-PEG1-NH2 dihydrochloride；VH 032 amide-PEG1-amineVH 032 amide-PEG1-amine；VH 032 amide-PE
Functionalized von-Hippel-Lindau (VHL) protein ligand for PROTAC research and development; incorporates an E3 ligase ligand plus a PEG linker ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. This product has been recently renamed. The previous name for this product was VH 032 - linker 9 PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.
价 格：￥电议型 号：T36264产 地：中国大陆
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T36256LC-2；化合物LC-2LC 2|||PROTAC KRASG12C Degrader-LC-2|||LC2；LC 2|||PROTAC KRASG12C Degrader-LC-2|||LC2
LC-2 (PROTAC KRASG12C Degrader-LC-2) is a novel von Hippel-Lindau-based PROTAC degrader of endogenous KRAS G12C with a DC50 between 0.25 and 0.76 μM.LC-2 is a PROTAC that covalently binds KRAS G12C with MRTX849 and recruits the E3 ligase, VH, to induce a rapid and sustained degradation of KRAS G12C. LC-2 inhibits MAPK signaling in pure and heterozygous KRAS G12C cell lines.
价 格：￥电议型 号：T36256产 地：中国大陆
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T35859Aldumastat；化合物 AldumastatGLPG1972|||S201086|||G504572；GLPG1972|||S201086|||G504572
Aldumastat (GLPG1972) is a highly potent, specific and orally active inhibitor of ADAMTS-5.Aldumastat is used for the study of osteoarthritis of the knee.
价 格：￥电议型 号：T35859产 地：中国大陆
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T3554RG14620；化合物RG 14620Tyrphostin RG14620|||RG 14620；Tyrphostin RG14620|||RG 14620
RG14620 (Tyrphostin RG14620) is an epidermal growth factor receptor (EGFR) inhibitor.
价 格：￥电议型 号：T3554产 地：中国大陆
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T35520Aflatoxin G1-13C17；Aflatoxin G1-13C17Aflatoxin G1-13C17；Aflatoxin G1-13C17
Aflatoxin G1-13C17is intended for use as an internal standard for the quantification of aflatoxin G1by GC- or LC-MS. Aflatoxin G1is a mycotoxin that has been found inA. terricola.1
价 格：￥电议型 号：T35520产 地：中国大陆
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T3545RG13022；化合物RG 13022RG 13022|||Tyrphostin RG13022；RG 13022|||Tyrphostin RG13022
RG13022 (Tyrphostin RG13022) is a tyrosine kinase inhibitor; inhibits the autophosphorylation reaction of the EGF receptor (IC50: 4 μM).
价 格：￥电议型 号：T3545产 地：中国大陆
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T34310RG 14921；化合物 T34310RG14921|||RG-14921；RG14921|||RG-14921
RG 14921 is a pyridone analog of erbstatin, epidermal growth factor (EGF) receptor tyrosine kinase, and cAMP-dependent kinase.
价 格：￥电议型 号：T34310产 地：中国大陆
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T33490m-PEG12-aldehyde；化合物 T33490m-PEG12-aldehyde
m-PEG12-aldehyde is a PEG derivative containing an aldehyde group. Aldehyde is reactive to hydrazide and aminooxy groups which are commonly used in biomolecular probes for labeling and crosslinking carbonyls (oxidized carbohydrates). The hydrophilic PEG spacer increases solubility in aqueous media.
价 格：￥电议型 号：T33490产 地：中国大陆
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T32285JE-2147；化合物 T32285JE2147|||AG 1776|||AG1776|||JE 2147|||AG-1776；JE2147|||AG 1776|||AG1776|||JE 2147|
JE-2147 belongs to a type of compound known as hybrid peptides. The compound contains at least two different kinds of amino acids (alpha, beta, gamma, delta) linked to each other through a peptide bond.
价 格：￥电议型 号：T32285产 地：中国大陆
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T32120Hydroxy-PEG1-methylamine；化合物 T32120Hydroxy-PEG1-methylamine
Hydroxy-PEG1-methylamine is a PEG derivative containing a hydroxyl group with a methylamine group. The hydrophilic PEG spacer increases solubility in aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The methylamine group is reactive with carboxylic acids, carbonyls (ketone, aldehyde) etc.
价 格：￥电议型 号：T32120产 地：中国大陆
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T32074Hgg 12；化合物 T32074Hgg-12|||Hgg12；Hgg-12|||Hgg12
Hgg 12 is used to treat organophosphorus poisoning.
价 格：￥电议型 号：T32074产 地：中国大陆
