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T6446ClevudineOrthopoxvirus,half-life,nucleoside,DNA/RNA Synthesis,analog,Inhibitor,polymerase,Hepatitis
Clevudine is a synthetic pyrimidine analogue with activity against hepatitis B virus (HBV). Intracellularly, clevudine is phosphorylated to its active metabolites, clevudine monophosphate and triphosphate. The triphosphate metabolite competes with thymidine for incorporation into viral DNA, thereby causing DNA chain termination and inhibiting the function of HBV DNA polymerase (reverse transcriptase). Clevudine has a long half-life and shows significant reduction of covalently closed circular DN
价 格：￥电议型 号：T6446产 地：中国大陆
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T35336Furosemide sodium
Furosemide sodium is a potent and orally active inhibitor of Na+/K+/2Cl- (NKCC) cotransporter, NKCC1 and NKCC2. Furosemide sodium is also a GABAA receptors antagonist and displays 100-fold selectivity for α6-containing receptors than α1-containing receptors. Furosemide sodium acts as a loop diuretic and used for the study of congestive heart failure, hypertension and edema.
价 格：￥电议型 号：T35336产 地：中国大陆
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T16873SERCA2a activator 1Ca channels,phospholamban,Inhibitor,Ca2+ channels,SERCA2a activator 1,SERCA2a,SER
SERCA2a activator 1 is a sarco/endoplasmic reticulum Ca2+-dependent ATPase 2a activator. SERCA2a activator 1 decreases phospholamban inhibition and enhances the systolic and diastolic functions of the heart.
价 格：￥电议型 号：T16873产 地：中国大陆
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T86486-AZATHYMINE6-Azathymine,6AZATHYMINE,antibacterial,nucleobase,Inhibitor,Influenza Virus,DNA,6-nitrog
6-azathymine is a potent inhibitors of D-3-aminoisobutyrate-pyruvate aminotransferase. 6-Azauracil acted as a competitive inhibitor with respect to beta-alanine, and was an uncompetitive inhibitor with respect to pyruvic acid with a Ki of approximately 8.9 mM.
价 格：￥电议型 号：T8648产 地：中国大陆
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T8484JSH-150CDK,inhibit,Cyclin dependent kinase,Inhibitor,JSH150,JSH-150,JSH 150
JSH-150 is a highly selective CDK9 inhibitor(IC50 : 1 nM).
价 格：￥电议型 号：T8484产 地：中国大陆
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T12262L1NPS ALX Compound 4a hydrochloride(1:1)NPSALXCompound4ahydrochloride(299433106Freebase)
NPS ALX Compound 4a hydrochloride(1:1) is a potent and selective 5-hydroxytryptamine6 (5-HT6) receptor antagonist, with an IC50 of 7.2 nM and a Ki of 0.2 nM.
价 格：￥电议型 号：T12262L1产 地：中国大陆
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T7181IDO-IN-1Inhibitor,inhibit,Indoleamine 2,3-Dioxygenase (IDO),IDO IN 1,IDOIN1
IDO-IN-1 is a potent indoleamine 2,3-dioxygenase (IDO) inhibitor( IC50 values of 59 and 12 nM for human IDO enzymatic activity and HeLa cell assays, respectively.)
价 格：￥电议型 号：T7181产 地：中国大陆
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T7798FGH10019FGH10019,FGH 10019,inhibit,Inhibitor,Fatty Acid Synthase (FASN)
FGH-10019 is a novel inhibitor of sterol regulatory element-binding protein (SREBP) ( IC50 :1 μM).
价 格：￥电议型 号：T7798产 地：中国大陆
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T7558CID-1067700ML282,competitively,CID1067700,brain,Rab7,ML 282,GTPase,Ras,machinery,Ras-related,CID-106
CID-1067700 is one of the first identified competitive inhibitors of nucleotide binding by Ras-related GTPases（Rab7 with a Ki of 13 nM).
价 格：￥电议型 号：T7558产 地：中国大陆
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TP1862L[Sar9] Substance P acetate(77128-75-7 free base)[Sar9] Substance P acetate(77128 75 7 free base),[Sa
[Sar9]-Substance P acetate is one of NK-1 receptor agonist. The action of SP on progesterone metabolism was mimicked by the rNK1-specific agonist [Sar-9,Met(O2)11]-SP.
价 格：￥电议型 号：TP1862L产 地：中国大陆
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T9623RORγt inverse agonist 13RORγt inverse agonist 13,ROR,RORγt inverse agonist-13,RAR-related orphan rec
RORγt inverse agonist 13 (Compound 3i) is a potent, orally active and selective RORγt inverse agonist (IC50=63.8 nM), with improved drug-like properties[1].
价 格：￥电议型 号：T9623产 地：中国大陆
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T8230PNU112455A hydrochlorideanticooperative,Cyclin dependent kinase,PNU112455A hydrochloride,Alzheimer’s
PNU 112455A is an ATP site competetive inhibitor of CDK2 and CDK5,binds to the ATP site of CDK2 and CDK5 with Kms of 3.6 and 3.2 μM, respectively.
价 格：￥电议型 号：T8230产 地：中国大陆
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TP1942L1pep2-AVKI acetate(1315378-69-8 free base)pep2AVKI acetate(1315378698 free base),pep2 AVKI acetate(13
Inhibitor peptide that selectively disrupts binding of the AMPA receptor subunit GluA2 (at the C-terminal PDZ site) to protein interacting with C kinase (PICK1). Does not affect binding of GluA2 to GRIP or ABP and does not increase AMPA current amplitude or affect long term depression (LTD).
价 格：￥电议型 号：TP1942L1产 地：中国大陆
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TQ0060LY2857785Cyclin dependent kinase,LY 2857785,CDK,Apoptosis,LY2857785,Inhibitor,inhibit,LY-2857785
LY2857785 is a type I competitive and reversible ATP kinase inhibitor against CDK7/CDK8/CDK9 (IC50s: 246 nM/16 nM/11 nM).
价 格：￥电议型 号：TQ0060产 地：中国大陆
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T64337PF-04745637PF04745637,Inhibitor,bowel,TRPA1,disease,inhibit,respiratory,PF-04745637,Transient recept
PF-04745637 is a potent and selective TRPA1 antagonist with an IC50 of 17 nM[1].
价 格：￥电议型 号：T64337产 地：中国大陆
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T6S1597Mulberroside AMulberroside A,Tumor Necrosis Factor Receptor,inhibit,TNF Receptor,Tyrosinase,TNFR,Inh
1. Mulberroside has nephroprotective, hypoglycemic, and antidiabetic effects. 2. Mulberroside A is a glycosylated stilbene of oxyresveratrol; thus, the deglycosylation of Mulberroside A resulted in enhanced inhibition of melanogenesis. 3. Mulberroside A has anti-inflammatory antiapoptotic effects. by decreasing the expressions of tumor necrosis factor-α (TNF-α), interleukin (IL)-1β, and IL-6 and inhibiting the activation of NALP3, caspase-1, and nuclear factor-κB and the phosphorylation of extra
价 格：￥电议型 号：T6S1597产 地：中国大陆
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TN1413AtranorinAP-1,Atranorin,Ras,metabolite,secondary,Wnt,inhibit,β-catenin,Lichen,STAT,Endogenous Metabo
Atranorin shows significant antinociceptive and antiinflammatory activities, it has a relevant redox-active action, acting as a pro-oxidant or antioxidant agent depending on the radical, also, it will exert cytoprotective effects on cells under oxidative stress induced by H(2)O(2).
价 格：￥电议型 号：TN1413产 地：中国大陆
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TQ0078CDK-IN-2Inhibitor,CDK IN 2,inhibit,CDK,Cyclin dependent kinase,CDKIN2
CDK-IN-2 is a potent and specific CDK9 inhibitor (IC50: <8 nM).
价 格：￥电议型 号：TQ0078产 地：中国大陆
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TP1875LCDK2 acetate(255064-79-0 free base)CDK2 acetate(255064790 free base),CDK-2 acetate(255064-79-0 free
CDK2 acetate is a member of the eukaryotic S/T protein kinase family and its function is to catalyze the phosphoryl transfer of ATP γ-phosphate to serine or threonine hydroxyl (denoted as S0/T0) in a protein substrate.
价 格：￥电议型 号：TP1875L产 地：中国大陆
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T6450ClinofibrateClinofibrate,HMG-CoA Reductase (HMGCR),Autophagy,inhibit,Inhibitor,S 8527,S8527
Clinofibrate（IC50 of 0.47 mM）, a lipid-lowering agent, inhibits hydroxymethylglutaryl coenzyme A reductase (HMGCR). It is utilized to control high cholesterol and triacylglyceride levels in the blood.
价 格：￥电议型 号：T6450产 地：中国大陆
